Effect of Long-Acting β2 Agonists on Exacerbation Rates of Asthma in Children

Pediatric Pulmonology

Volumn 36, Issue 5, 2003, Pages 391-398

  Bisgaard, Hans ^a  

^a Mental Health Services CPH   (Denmark)

Author keywords

Asthma; Children; Exacerbations; Formoterol; Long acting 2 agonists; Salmeterol

Indexed keywords

BECLOMETASONE DIPROPIONATE; BETA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; BUDESONIDE; FORMOTEROL; SALMETEROL;

ARTICLE; ASTHMA; CHILD; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DISEASE EXACERBATION; DRUG EFFECT; HOSPITALIZATION; HUMAN; MAINTENANCE THERAPY; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RISK ASSESSMENT; SYMPTOMATOLOGY;

ADMINISTRATION, INHALATION; ADOLESCENT; ADRENAL CORTEX HORMONES; ASTHMA; CHILD; CHILD, PRESCHOOL; DISEASE PROGRESSION; DRUG THERAPY, COMBINATION; HOSPITALIZATION; HUMANS; PLACEBO EFFECT; RANDOMIZED CONTROLLED TRIALS; RECEPTORS, ADRENERGIC, BETA-2; RISK ASSESSMENT; TREATMENT OUTCOME;

EID: 0142126269     PISSN: 87556863     EISSN: None     Source Type: Journal    
DOI: 10.1002/ppul.10381     Document Type: Article

References (28)

1. NHLBI/WHO workshop report: Global strategy for asthma management and prevention. Issued January, 1995. NIH Publication No 02-3659. Revised 2002; www.ginasthma.com
2. Woolcock A, Lundback B, Ringdal N, Jacques LA. Comparison of addition of salmeterol to inhaled steroids with doubling of the dose of inhaled steroids. Am J Respir Crit Care Med 1996;153:1481-1488.
3. Vermetten FAAM, Boermans AJM, Luiten WDVF, Mulder PGH, Vermue NA. Comparison of salmeterol with beclomethasone in adult patients with mild persistent asthma who are already on low-dose inhaled steroids. J Asthma 1999;6:97-106.
4. Pauwels RA, Löfdahl C-G, Postma DS, Tattersfield AE, O'Byrne P, Barnes PJ, Ullman A. Effect of inhaled formoterol and budesonide on exacerbations of asthma. N Engl J Med 1997;337:1405-1411.
5. Bisgaard H. Long-acting beta2-agonist in management of childhood asthma: a critical review of the literature. Pediatr Pulmonol 2000;29:221-234.
6. Zarkovic J, Goetz MH, Holgate ST, Taak NK. Effect of long-term regular salmeterol treatment in children with moderate asthma. Clin Drug Invest 1998;15:169-175.
7. Akpinarli A, Tuncer A, Saraclar Y, Sekerel BE, Kalayci Ö. Effect of formoterol on clinical parameters and lung functions in patients with bronchial asthma: a randomized controlled trial. Arch Dis Child 1999;81:45-48.
8. Bensch G, Berger WE, Blokhin BM, Socolovsky AL, Thompson MH, Till MD, Castellsague J, Della-Cioppa G. One year efficacy and safety of inhaled formoterol dry powder in children with persistent asthma. Ann Allergy Asthma Immunol 2002;89:180-190.
9. Lenney W, Pederson S, Boner AL, Ebbutt A. Efficacy and safety of salmeterol in childhood asthma. Eur J Pediatr 1995;154:983-990.
10. Verberne AAPH, Frost C, Duiverman EJ, Grol MH, KetTibijn KF. Addition of salmeterol versus doubling the dose of beclomethasone in children with asthma. Am J Respir Crit Care Med 1998;158:213-219.
11. Von Berg A, De Blic J, La Rosa M, Kaad PH, Moorat A. A comparison of regular salmeterol versus "as required" salbutamol therapy in asthmatic children. Respir Med 1998;92:292-299.
12. Langton Hewer S, Hobbs J, French D, Lenney W. Pilgrim's progress: the effect of salmeterol in older children with chronic severe asthma. Respir Med 1995;89:435-440.
13. Tal A, Simon G, Vermeulen JH, Petru V, Cobos N, Everard ML, de Boeck K. Budesonide/formoterol in a single inhaler vs. inhaled corticosteroids alone in the treatment of asthma. Pediatr Pulmonol 2002;34:342-350.
14. Kleinbaum DG, Kupper LL, Morgenstern H. Epidemiologic research, principles and quantitative methods. New York: Van Nostrand Reinhold; 1982.
15. Shrewsbury S, Pyke S, Britton M. Meta-analysis of increased dose of inhaled steroid or addition of salmeterol in symptomatic asthma (MIASMA). Br Med J [Clin Res] 2000;320:1368-1373.
16. Price D, Dutchman D, Mawson A, Bodalia B, Duggan S, Todd P. Early asthma control and maintenance with eformoterol following reduction of inhaled corticosteroid dose. Thorax 2002;57:791-798.
17. O'Byrne PM, Barnes PJ, Rodriguez-Roisin R, Runnerstrom E, Sandstrom T, Svensson K, Tattersfield A. Low dose inhaled budesonide and formoterol in mild persistent asthma: the OPTIMA randomized trial. Am J Respir Crit Care Med 2001;164:1392-1397.
18. Sears MR, Taylor DR, Print CG, Lake DC, Qingqing L, Flannery EM, Yates DM, Lucas MK, Herbison GP. Regular inhaled beta-agonist treatment in bronchial asthma. Lancet 1990;336:1391-1396.
19. Van Schayck CP, Dompeling E, van Herwaarden CLA, Folgering H, Veerbeck ALM, van der Hoogen HJM, van Weel C. Bronchodilator treatment in moderate asthma or chronic bronchitis: continuous or on demand? A randomized controlled study. Br Med J [Clin Res] 1991;303:1426-1431.
20. Castle W, Fuller R, Hall J, Palmer J. Serevent Nationwide Surveillance Study: comparison of salmeterol with salbutamol in asthmatic patients who require regular bronchodilator treatment. Br Med J [Clin Res] 1993;306:1034-1037.
21. Wooltorton E. Salmeterol (Serevent) asthma trial halted early. JAMC 2003;168:738.
22. Simons FER, Gerstner TV, Cheang MS. Tolerance to the bronchoprotective effect of salmeterol in adolescents with exercise-induced asthma using concomitant inhaled glucocorticoid treatment. Pediatrics 1997;99:655-659.
23. Villaran C, O'Neill SJ, Helbling A, van Noord JA, Lee TH, Chuchalin AG, Langley SJ, Gunawardena KA, Suskovic S, Laurenzi M, Jasan J, Menten J, Leff JA. Montelukast versus salmeterol in patients with asthma and exercise-induced bronchoconstriction. Montelukast/Salmeterol Exercise Study Group. J Allergy Clin Immunol 1999;104:547-553.
24. Edelman JM, Turpin JA, Bronsky EA, Grossman J, Kemp JP, Ghannam AF, DeLucca PT, Gormley GJ, Pearlman DS. Oral montelukast compared with inhaled salmeterol to prevent exercise-induced bronchoconstriction. A randomized, double-blind trial. Exercise Study Group. Ann Intern Med 2000;132:97-104.
25. Wilson AM, Dempsey OJ, Sims EJ, Lipworth BJ. Evaluation of salmeterol or montelukast as second-line therapy for asthma not controlled with inhaled corticosteroids. Chest 2001;119:1021-1026.
26. Verberne AAPH, Frost C, Roorda RJ, van der Laag H, Kerebijn KF. One year treatment with salmeterol compared with beclomethasone in children with asthma. Am J Respir Crit Care Med 1997;156:688-695.
27. Lazarus SC, Boushey HA, Fahy JV, Chinchilli VM, Lemanske RF Jr, Sorkness CA, Kraft M, Fish JE, Peters SP, Craig T, Drazen JM, Ford JG, Israel E, Martin RJ, Mauger EA, Nachman SA, Spahn JD, Szefler SJ. Long-acting beta2-agonist monotherapy vs. continued therapy with inhaled corticosteroids in patients with persistent asthma: a randomized controlled trial. JAMA 2001;285:2583-2593.
28. Lemanske RF Jr, Sorkness CA, Mauger EA, Lazarus SC, Boushey HA, Fahy JV, Drazen JM, Chinchilli VM, Craig T, Fish JE, Ford JG, Israel E, Kraft M, Martin RJ, Nachman SA, Peters SP, Spahn JD, Szefler SJ. Inhaled corticosteroid reduction and elimination in patients with persistent asthma receiving salmeterol: a randomized controlled trial. JAMA 2001;285:2594-2603.