Effects of maternal exposure to picrotoxin during lactation on physical and reflex development, square crossing and sexual behavior of rat offspring

Pharmacology Biochemistry and Behavior

Volumn 75, Issue 4, 2003, Pages 733-740

  Baso, A C Z ^a   Goulart, F C ^a   Teodorov, E ^a   Felicio L F ^a   Bernardi, M M ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Lactation; Picrotoxin; Rat

Indexed keywords

NEUROTRANSMITTER; PICROTOXIN;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BODY WEIGHT; CONTROLLED STUDY; DOPAMINERGIC SYSTEM; EJACULATION; ENVIRONMENTAL EXPOSURE; FEMALE; FLUID INTAKE; FOOD INTAKE; GABAERGIC TRANSMISSION; INTOXICATION; LACTATION; MALE; MATERNAL BEHAVIOR; NEWBORN; NONHUMAN; PERINATAL PERIOD; PHYSICAL DEVELOPMENT; PRIORITY JOURNAL; PROGENY; RAT; REFLEX RECRUITMENT; SEIZURE; SEXUAL BEHAVIOR;

ANIMALIA;

EID: 0142106492     PISSN: 00913057     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0091-3057(03)00146-1     Document Type: Article

References (47)

1. Agmo A., Paredes R., Fernandez H. Differential effects of GABA transaminase inhibitors on sexual behavior, locomotion activity, and motor execution in male rat. Pharmacol. Biochem. Behav. 28:1987;47-52.
2. Ahlenius S., Larsson K., Svensson L. Further evidence for an inhibitory role of central 5-HT in male rat sexual behavior. Psychopharmacology. 68:1980;217-220.
3. Ahlenius S., Larsson L., Svensson L., Hjorts S., Carlsson A., Lindberg P.et al. Effects of a new type of 5-HT receptor agonist on male rat sexual behavior. Pharmacol. Biochem. Behav. 15:1981;785-792.
4. Ahlenius S., Carlsson A., Hillegaart V., Hjorth S., Larsson K. Region-selective activation of brain monoamine synthesis by sexual activity in the male rat. Eur. J. Pharmacol. 144:1987;77-82.
5. Altman J., Sudarshan K. Postnatal development of locomotion in the laboratory rat. Anim. Behav. 23:1975;896-920.
6. A receptors display association of γ2-subunit with α1- and β2/3 subunits. J. Biol. Chem. 266:1991;4478-4483.
7. Cagiano R., De Salvia M.A., Persichella M., Renna G., Tattoli M., Cuomo V. Behavioral changes in the offspring of rats exposed to diazepam during gestation. Eur. J. Pharmacol. 177:1990;67-69.
8. Carlos C.P., Lemonica Y.P., Kempinas W.G., Pereira O.C.M. Does the male reproductive performance depend on the early lactation milk in rats? Physiol. Behav. 59:1996;147-152.
9. Cherubini E., Gaiarsa J.L., Bem-Ari Y. GABA: an excitatory transmitter in early postnatal life. Trends. Neurosci. 14:1991;515-519.
10. Chiavegatto S., Bernardi M.M., De-Souza-Spinosa H. Effects of prenatal diphenhydramine administration on sexual behavior of rats. Braz. J. Med. Biol. Res. 22:1989;729-732.
11. Chronwall B., Wolff J.R. Prenatal and postnatal development of GABA-accumulating cells in the occipital neocortex of rat. J. Comp. Neurol. 190:1980;187-208.
12. Felicio L.F., Nasello A.G. Effect of acute bromopride on rat prolactin levels and sexual behavior. Braz. J. Med. Biol. Res. 22:1989;1011-1014.
13. Fernández-Guasti A., Larsson K., Beyer C. Comparison of the effects of different isomers of bicuculline infused in the preoptic area on male rat sexual behavior. Experientia. 41:1985;1414-1416.
14. Fernández-Guasti A., Larsson K., Beyer C. GABAergic control of masculine sexual behavior. Pharmacol. Biochem. Behav. 24:1986;1065-1070.
15. Fieder B., Epstein S., Grimm V.E. The effects of exposure to diazepam during various stages of gestation or during lactation on the development and behavior of rat pups. Psychopharmacology. 83:1984;51-55.
16. Fisman M.L., Behar T., Lange G.D., Smith S.V., Novotny E.A., Barker J.L. GABAergic cells and signals appear together in the early post-mitotic period of telencephalic and striatal development. Dev. Brain Res. 73:1993;243-251.
17. A-receptor heterogeneity in the adult rat brain: differential regional and cellular distribution of seven major subunits. J. Comp. Neurol. 359:1995;154-194.
18. Fritschy J.M., Paysan J., Enna A., Mohler H. Switch in the expression of rat GABAA receptor subtypes during postnatal development: an immunohistochemical study. J. Neurosci. 14:1994;5302-5324.
19. Fuxe K., Kölkelt T., Ljungdahl A., Agnati L., Johansson O., Perez de La Mora M. Evidence for an inhibitory GABAergic control of the mesolimbic dopamine neurons: possibility of improving treatment of schizophrenia by combined treatment with neuroleptics and GABAergic drugs. Med. Biol. 53:1975;177-183.
20. Gessa G.L., Tagliamonte A. Role of brain serotonin and dopamine in male sexual behavior. Sandler M., Gessa G.L. Pharmacology and biochemistry. 1975;Raven Press, New York. 117 pp.
21. A-receptor in the marmoset monkey: expression of distinct subtypes in pre- and postnatal brain. J. Comp. Neurol. 367:1996;413-430.
22. Hucke E.E., Cruz-Casallas P.E., Florio J.C., Felicio L.F. Reproductve experience reduces striatal dopaminergic responses in freely moving female rats. Neuroreport. 9:1998;3589-3593.
23. Hull E.M., Bitran D., Pehek E.A., Warner R.K., Band L.C., Holmes G.M. Dopaminergic control of male sex behavior in rats: effects of an intracerebrally-infused agonist. Brain Res. 370:1986;73-81.
24. Hull E.M., Lorrain D.S., Matuszewich L., Lumley L.A., Putnam S.K., Moses J. Hormone-neurotransmitter interactions in the control of sexual behavior. Behav. Brain Res. 105:1999;105-1116.
25. Johnson N., Leone F. Statistics and experimental design. Engineering and physiological sciences. 1974;241-244 Wiley, New York.
26. Kacsóh B., Nagy G.Y., Veress Z., Toth B.E., Kanyicska B., Csernus V.et al. Data suggesting that milk of early lactation period might be involved in sexual differentiation of rat brain. Endocrinology. 20:1986;155-166.
27. Kellogg C., Tervo D., Ison J., Parisi L. Prenatal exposure to diazepam alters behavioral development in rats. Science. 207:1980;205-207.
28. Lauder J.M., Han V.K.M., Henderson P., Verdoorn T., Towle A.C. Prenatal ontogeny of the GABAergic system in the rat brain: an immunocytochemical study. Neuroscience. 19:1986;465-493.
29. Laurie D.J., Seeburg P.H., Wisden W. The distribution of 13 GABAA receptor subunit mRNAs in the rat brain: II. Olfactory bulb and cerebellum. J. Neurosci. 12:1992;1063-1076.
30. Lloyd K.G., Worms P., Zivkovic O., Sactton B., Bartholini G. Interaction of GABA mimetics with nigro striatal dopamine neurons. Brain. Res. Bull. 5:1980;439-445.
31. Lyubimov B.I., Smolmikova N.M., Strekolova S.N. Effects of diazepam on development of the offspring. Bull. Exp. Biol. Med. 78:1975;1156-1158.
32. Ma W., Behar T., Barke J.L. Transient expression of GABA immunoreactivity in the developing rat spinal cord. J. Comp. Neurol. 235:1992;271-290.
33. A receptor subunit mRNAs in rat spinal cord and dorsal rat ganglia. J. Comp. Neurol. 338:1993;337-359.
34. Malmnãs C.O. Monoaminergic influence on testosterone-activated copulatory behavior in castrated male rat. Acta Physiol. Scand. Suppl. 395:1973;1-128.
35. Malmnãs C.O. The significance of dopamine, versus other catecholamines, for L-DOPA induced facilitation of sexual behavior in the castrated male rat. Pharmacol. Biochem. Behav. 4:1976;521-526.
36. Manning D.E., Stoud A.G., Jemp J.W. Effects of maternal phenobarbital administration on same aspects of neonatal brain development. Fed. Proc. Fed. Am. Soc. Exp. Biol. 30:1971;495.
37. Mas M., Del Castillo A.R., Guerra M., Davidson J.M., Battaner E. Neurochemical correlates of male sexual behavior. Physiol. Behav. 41:1987;341-345.
38. Meyerson B.J., Palis A., Sietnieks A. Hormone-monoamine interactions and sexual behavior. Beyer C. Endocrine control of sexual behavior. 1979;Raven Press, New York. 389 pp.
39. Middaugh L.D., Santos C.A. III, Zemp J.W. Effects of phenobarbital given to pregnant mice on behavior of mature offspring. Dev. Psychobiol. 8:1975;305.
40. Paredes R.G., Agmo A. GABA and behavior: the role of receptor subtypes. Neurosci. Biobehav. Rev. 16:1992;145-170.
41. A- receptor α1-subunit: an early marker of cortical parcellation. J. Comp. Neurol. 350:1994;133-149.
42. Perez de La Mora M., Fuxe K., Hökfelt T., Ljungdahl A. Effect of apomorphine on the GABA turnover in the DA cell rich area of the mesencephalon. Evidence of the involvement of an inhibitory GABAergic feedback control of the ascending DA neurons. Neurosci. Lett. 1:1975;104-114.
43. Poulter M.O., Barker J.L., O'Carrol A.M., Lolait S.J., Mahan L.C. Co-existence expression of GABAA receptor β2, β3, and γ2 subunit messenger RNAs during embryogenesis and early postnatal development on the rat central nervous system. Neuroscience. 53:1993;1019-1033.
44. Silva M.R.P., Oliveira C.A., Felicio L.F., Nasello A.G., Bernardi M.M. Perinatal treatment with picrotoxin induces sexual, behavioral and neuroendocrine changes in male rats. Pharmacol. Biochem. Behav. 60:1998;203-208.
45. Smart J.L., Dobbing J. Vulnerability of developing brain: II. Effects of early nutritional deprivation on reflex ontogeny and development of behaviour on the rat. Brain Res. 28:1971;85-95.
46. Soderstein P., Eneroth P. Effects of exposure to pups on maternal behaviour, sexual behaviour and serum prolactin concentrations in male rats. J. Endocrinol. 102:1984;115-119.
47. Teodorov E., Salzgeber S.A., Felício L.F., Varolli F.M., Bernardi M.M. Effects of perinatal picrotoxin and sexual experience on heterosexual and homosexual behavior in male rats. Neurotoxicol. Teratol. 24:2002;235-245.