Toxicological diversity: Making room for the U-shaped dose-response

Human and Experimental Toxicology

Volumn 22, Issue 9, 2003, Pages 465-466

  Calabrese, Edward J ^a  

^a UNIVERSITY OF MASSACHUSETTS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL MODEL; CANCER RISK; CHEMICAL CARCINOGENESIS; CLINICAL PROTOCOL; DOSE RESPONSE; ECOTOXICOLOGY; EDITORIAL; EXPERIMENTAL DESIGN; HAZARD ASSESSMENT; HUMAN; HYPOTHESIS; MEDICAL RESEARCH; NONHUMAN; PRIORITY JOURNAL; PROCESS OPTIMIZATION; REGULATORY MECHANISM; RISK ASSESSMENT; STATISTICAL MODEL; TOXICITY TESTING; TOXICOLOGY;

ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; RISK ASSESSMENT; TOXICITY TESTS; XENOBIOTICS;

ANIMALIA;

EID: 0142106356     PISSN: 09603271     EISSN: None     Source Type: Journal    
DOI: 10.1191/0960327103ht386ed     Document Type: Editorial

References (2)

1. Calabrese EJ, Baldwin LA. The frequency of U-shaped dose-responses in the toxicological literature. Tox Sci 2001; 62: 330-38.
2. Calabrese EJ, Baldwin, LA. The hormetic dose-response model is more common than the threshold model in toxicology. Tax Sci 2003; 71: 246-50.