Absence of activation of CMV by blood transfusion to HIV-infected, CMV-seropositive patients

Transfusion

Volumn 43, Issue 10, 2003, Pages 1351-1357

  Drew, W Lawrence ^a   Chou, Sunwen ^b   Mohr, Beth A ^b   Assmann, Susan F ^b   Miner, Richard C ^b   Laycock, Megan E ^b   Busch, Michael P ^b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

VIRUS DNA; VIRUS ENVELOPE PROTEIN;

ARTICLE; BLOOD DONOR; BLOOD TRANSFUSION; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CYTOMEGALOVIRUS; DOUBLE BLIND PROCEDURE; GENOTYPE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; LEUKOCYTE TRANSFUSION; MAJOR CLINICAL STUDY; MULTICENTER STUDY; NONHUMAN; POLICY; POLYMERASE CHAIN REACTION; RANDOMIZED CONTROLLED TRIAL; SEQUENCE ANALYSIS; SUPERINFECTION; VIREMIA; VIRUS ACTIVATION; VIRUS LOAD; VIRUS REPLICATION; VIRUS STRAIN; VIRUS TRANSMISSION; BLOOD; CYTOMEGALIC INCLUSION BODY DISEASE; DISEASE TRANSMISSION; PHYSIOLOGY; VIROLOGY;

BLOOD TRANSFUSION; CYTOMEGALOVIRUS; CYTOMEGALOVIRUS INFECTIONS; DNA, VIRAL; HIV INFECTIONS; HUMANS; VIREMIA; VIRUS ACTIVATION;

EID: 0142103777     PISSN: 00411132     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1537-2995.2003.00520.x     Document Type: Article

References (16)

1. Lang DJ. Cytomegalovirus infections in organ transplantation and post transfusion. An hypothesis. Archiv fur die gesamte Virusforschung. 1972;37:365-72.
2. Adler SP, Baggett J, McVoy M. Transfusion-associated cytomegalovirus infections in seropositive cardiac surgery patients. The Lancet 1985;2:743-7.
3. Drew WL, Mocarski ES, Sweet E, Miner RC. Multiple infections by cytomegalovirus in patients with acquired immunodeficiency syndrome: documentation by Southern blot hybridization. J Infect Dis 1984;150:952-3.
4. Spector SA, Hirata KK, Newman TR. Identification of multiple cytomegalovirus strains in homosexual men with acquired immunodeficiency syndrome. J Infect Dis 1984;150:953-6.
5. Collier AC, Kalish LA, Busch MP, et al. Leukocyte-reduced red blood cell transfusions in patients with anemia and human immunodeficiency virus infection. The Viral Activation Transfusion Study: a randomized controlled trial. JAMA 2001;285:1592-601.
6. Busch MP, Collier A, Gernsheimer T, et al. The Viral Activation Transfusion Study (VATS): rationale, objectives, and design overview. Transfusion 1996;36:854-9.
7. Yomtovian R, Gernsheimer T, Assmann SF, et al. Viral Activation Transfusion Study Group. WBC reduction in RBC concentrates by prestorage filtration: multicenter experience. Transfusion 2001;41:1030-6.
8. Long CM, Drew L, Miner R, et al. Detection of cytomegalovirus in plasma and cerebrospinal fluid specimens from human immunodeficiency virus-infected patients by the AMPLICOR CMV test. J Clin Microbiol 1998;36:2434-8.
9. Bowden RA, Slichter SJ, Sayers M, et al. A comparison of filtered leukocyte-reduced and cytomegalovirus (CMV) seronegative blood products for the prevention of transfusion-associated CMV infection after marrow transplant. Blood 1995;86:3598-603.
10. Chou S, Dennison KM. Analysis of interstrain variation in cytomegalovirus glycoprotein B sequences encoding neutralization-related epitopes. J Infect Dis 1991;163:1229-34.
11. Brecher ME, Triulzi DJ, Assmann SF. Number of RBC units and rate of transfusion to anemic HIV positive patients assigned to receive WBC-reduced or non-WBC-reduced RBCs: the viral activation transfusion study experience. Transfusion 2001;41:794-8.
12. Cheung KS, Lang DJ. Transmission and activation of cytomegalovirus with blood transfusion: a mouse model. J Infect Dis 1977;135:841-5.
13. Ho M. Epidemiology of cytomegalovirus infection in man. In: Greenough WB, Merigan TC, eds. Cytomegalovirus biology and infection: current topics in infectious disease. New York: Plenum Publishing, 1982:79-104.
14. Chou S. Differentiation of cytomegalovirus strains by restriction analysis of DNA sequences amplified from clinical specimens. J Infect Dis 1990;162:738-42.
15. Chou S, Erice A, Jordan MC, et al. Analysis of the UL97 phosphotransferase coding sequence in clinical cytomegalovirus isolates and identification of mutations conferring ganciclovir resistance. J Infect Dis 1995;171:576-83.
16. Roback JD, Drew WL, Laycock ME, et al. Cytomegalovirus DNA is rarely detected in healthy blood donors using validated PCR assays. Transfusion 2003;43:314-21.