Use of nuclear scintigraphy with 99mTc-HMPAO-labelled leucocytes to assess small intestinal malabsorption in 17 horses

Veterinary Record

Volumn 153, Issue 15, 2003, Pages 457-462

  Menzies Gow, N J ^a   Weller, R ^a   Bowen, I M ^a   Corley, K T T ^a   Livesey, L ^a   Weaver, M ^b   Marr, C M ^a  

^a ROYAL VETERINARY COLLEGE   (United Kingdom)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTHELMINTIC AGENT; DEXAMETHASONE; HEXAMETHYLPROPYLENE AMINE OXIME TECHNETIUM TC 99M; NANDROLONE; PREDNISOLONE; DIAGNOSTIC AGENT; RADIOPHARMACEUTICAL AGENT;

ARTICLE; CELL LABELING; CLINICAL EXAMINATION; DIAGNOSTIC ERROR; DIAGNOSTIC VALUE; ENTEROPATHY; GASTROINTESTINAL TRACT SCINTISCANNING; HISTOPATHOLOGY; HORSE DISEASE; INTESTINE ABSORPTION; LEUKOCYTE; MALABSORPTION; MEDICAL ASSESSMENT; NONHUMAN; PREDICTION; PROGNOSIS; RECTUM BIOPSY; SENSITIVITY AND SPECIFICITY; TREATMENT OUTCOME; WEIGHT REDUCTION; ANIMAL; ANIMAL DISEASE; BLOOD; CASE CONTROL STUDY; EVALUATION; FEMALE; GLUCOSE TOLERANCE TEST; HORSE; MALE; PHYSIOLOGY; PREDICTION AND FORECASTING; SCINTISCANNING; STANDARD;

EQUIDAE; EQUUS CABALLUS;

ANIMALS; CASE-CONTROL STUDIES; FEMALE; GLUCOSE TOLERANCE TEST; HORSE DISEASES; HORSES; LEUKOCYTES; MALABSORPTION SYNDROMES; MALE; PREDICTIVE VALUE OF TESTS; RADIONUCLIDE IMAGING; RADIOPHARMACEUTICALS; TECHNETIUM TC 99M EXAMETAZIME;

EID: 0142074371     PISSN: 00424900     EISSN: None     Source Type: Journal    
DOI: 10.1136/vr.153.15.457     Document Type: Article

References (29)

1. ABURANO, T., SAITO, Y., SHUKE, N., AYABE, T., KOHGO, Y. & ISHIKAWA, Y. (1998) Tc-99m leukocyte imaging for evaluating disease severity and monitoring treatment response in ulcerative colitis: comparison with colonoscopy. Clinical Nuclear Medicine 23, 509-513
2. ALBERINI, J. L., BADRAN, A., FRENEAUX, E., HADJI, S., KALIFA, G., DEVAUX, J. Y. & DUPONT, T. (2001) Technetium-99m HMPAO-labelled leukocyte imaging compared with endoscopy, ultrasonography, and contract radiology in children with inflammatory bowel disease. Journal of Pediatric Gastroenterology and Nutrition 32, 278-286
3. BATT, R. M. (1990) Malabsorption in dogs. In Practice 12, 21-24
4. BENNINK, R., PEETERS, M., D'HAENS, G., RUTGEERTS, P. & MORTELMANS, L. (2001) Tc-99m HMPAO white blood cell scintigraphy in the assessment of the extent and severity of an acute exacerbation of ulcerative colitis. Clinical Nuclear Medicine 26, 99-104
5. BUTSON, R. J., WEBBON, P. M. & FAIRBAIRN, S. M. (1995) Tc-99m-HMPAO labelled leucocytes and their biodistribution in the horse: a preliminary investigation. Equine Veterinary Journal 27, 313-315
6. CARROLL, K. (1998) Crohn's disease: new imaging techniques. Bailliere's Clinical Gastroenterology 12, 35-72
7. 111In-oxine. American Journal of Veterinary Research 53, 871-875
8. DAVISON, S. M., CHAPMAN, S. & MURPHY, M. S. (2001) 99mTc-HMPAO leucocyte scintigraphy fails to detect Crohn's disease in the proximal gastrointestinal tract. Archive's of Disease in Childhood 85, 43-46
9. EAST, L. M., TRUMBLE, T. N., STEYN, P. F., SAVAGE, C. J., DICKINSON, C. E. & TRAUB-DARGATZ, J. L. (2000) The application of technetium-99m hexamethylpropyleneamine oxime (99mTc-HMPAO) labelled white blood cells for the diagnosis of right dorsal ulcerative colitis in two horses. Veterinary Radiology and Ultrasound 4, 360-364
10. FOREMAN, J. H. (1998) Diseases of the small intestine. In Equine Internal Medicine. Eds S. M. Reed, W. M. Bayly. Philadelphia, W. B. Saunders. pp 637-636
11. KEMPER, D. L., PERKINS, G. A., SCHUMACHER, J., EDWARDS, J. F., VALENTINE, B. A., DIVERS, T. J. & COHEN, N. A. (2000) Equine lymphocytic-plasmacytic enterocolitis: a retrospective study of 14 cases. Equine Veterinary Journal Supplement 32, 108-112
12. LANTTO, E., JARVI, K., KREKELA, I., LANTTO, T., TAAVITSAINEN, M. & VEDENKANGAS, H. (1992) Technetium-99m hexamethyl propylene amine oxine leucocytes in the assessment of disease activity in inflammatory bowel disease. European Journal of Nuclear Medicine 19, 14-18
13. LATTIMER, J. C., REED, A. L. & JOHNSON, P. J. (1995) Preliminary results of 99mTc HMPAO labelled leucocyte scintigraphy in horses. Veterinary Radiology and Ultrasound 36, 363
14. LINDBERG, R. (1984) Pathology of equine granulomatous enteritis. Journal of Comparative Pathology 94, 233-247
15. LINDBERG, R., NYGREN, A. & PERSSON, S. G. (1996) Rectal biopsy in horses with clinical signs of intestinal disorders: a retrospective study of 116 cases. Equine Veterinary Journal 28, 275-284
16. LINDBERG, R., PERSSON, S. G. B., JONES, B., THOREN-TOLLING, K. & EDEROTH, M. (1985) Clinical and pathological features of granulomatous enteritis and eosinophilic granulomatosis in the horse. Journal of Veterinary Medicine 32, 526-539
17. LONG, C. D., GALUPPO, L. D., WATERS, N. & HORNOF, W. J. (2000) Scintigraphic detection of equine orthopaedic infection using Tc-HMPAO labelled leucocytesin 14 horses. Veterinary Radiology and Ultrasound 41, 354-359
18. LOVE, S., MAIR, T. S. & HILLYER, M. H. (1992) Chronic diarrhoea in adult horses: a review of 51 referred cases. Veterinary Record 130, 217-219
19. MAIR, T. S., HILLYER, M. H., TAYLOR, F. G. R. & PEARSON, G. R. (1991) Small intestinal malabsorption in the horse, an assessment of the specificity of the oral glucose tolerance test. Equine Veterinary Journal 23, 344-346
20. MERRITT, A. M., CIMPRICH, R. E. & BEECH, J. (1976) Granulomatous enteritis in nine horses. Journal of the American Veterinary Medical Association 169, 603-609
21. MOLNAR, T., PAPOS, M., GYULAT, C., AMBRUS, E., KARDOS, L., NAGY, F., PALKO, A., PAVICS, L. & LONOVICS, J. (2001) Clinical value of technetium-99m-HMPAO-labeled leukocyte scintigraphy and spinal computed tomography in active Crohn's disease. American Journal of Gastroenterology 96, 1517-1521
22. MURRAY, M. J. (1988) Digestive physiology of the large intestine in adult horses. Part I. Mechanisms of fluid, ions and volatile fatty acid transport. Compendium on Continuing Education for the Practicing Veterinarian 10, 1204-1210
23. ROBERTS, M. C. (1985) Malabsorption syndromes in the horse. Compendium on Continuing Education for the Practicing Veterinarian 7, 637-646
24. ROBERTS, M. C. & HILL, F. W. G. (1973) The oral glucose tolerance test in the horse. Equine Veterinary Journal 5, 171-173
25. RODDIE, M. E., PETERS, A. M., OSMAN, S., DANPURE, H. J., LAVENDER, J. P. & NEIRINCKX, R. D. (1988) Osteomyelitis. Nuclear Medicine Communications 9, 713-717
26. SCHUMACHER, J., EDWARDS, J. F. & COHEN, N. D. (2000) Chronic idiopathic inflammatory bowel diseases of the horse. Journal of Veterinary Internal Medicine 14, 258-265
27. TAYLOR, F. G. R., HILLYER, M. H. & EDWARDS, G. B. (1997) Abdominal diagnostics. In Diagnostic Techniques in Equine Medicine. Eds F. G. R. Taylor, M. H. Hillyer. Philadelphia, W. B. Saunders. pp 56-57
28. VORNE, M., LAITINEN, R., LANTTO, T., JARVI, K., TOIVIO, I. & MOKKA, R. (1991) Chronic prosthetic vascular graft infection visualised with technetium-99m-hexamethylpropyleneamine oxime-labelled leukocytes. Journal of Nuclear Medicine 32, 1425-1427
29. WELDON, M. J., LOWE, C., JOSEPH, A. E. & MAXWELL, J. D. (1996) Review article: quantitative leucocyte scanning in the assessment of inflammatory bowel disease activity and its response to therapy. Alimentary Pharmacology and Therapeutics 10, 123-132