Influence of Hypoxia, Chemoreceptors, and Sympathetic Activity in Chronic Hypertension in the Rat

Sleep Apnea: Implications in Cardiovascular and Cerebrovascular Disease: Volume 146

Volumn 146, Issue , 2000, Pages 181-212

  Fletcher, Eugene C ^a   Bao, Gang ^a  

^a University of Louisville School of Medicine   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0142067211     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1201/b15277-12     Document Type: Chapter

References (58)

1. Guilleminault C, Tilkian A, Dement WC. The sleep apnea syndromes. Annu Rev Med 1976; 27:465-484.
2. Tilkian AG, Guilleminault C, Schroeder JS, Lehrman KL, Simmons FB, Dement WC. Hemodynamics in sleep-induced apnea: studies during wakefulness and sleep. Ann Intern Med 1976; 85:714-719.
3. Lugaresi E, Coccagna G, Cirignotta F, et al. Breathing during sleep in man in normal and pathological conditions. Adv Exp Med Biol 1978; 99:35-45.
4. Lavie P, Ben-Yosef R, Rubin AE. Prevalence of sleep apnea syndrome among patients with essential hypertension. Am J Cardiol 1985; 55:1019-1022.
5. Kales A, Cadieux RJ, Shaw LC, Vela-Bueno A, Bixler EO, Schneck DW, Locke TW, Soldatos CR. Sleep apnoea in a hypertensive population. Lancet 1984; 2:10051008.
6. Fletcher EC, DeBehnke RD, Lovoi MS, Gorin AB. Undiagnosed sleep apnea in patients with essential hypertension. Ann Intern Med 1985; 103:190-195.
7. Williams AJ, Houston D, Finberg S, Lam C, Kinney JL, Santiago S. Sleep apnoea syndromes and essential hypertension. Am J Cardiol 1985; 55:1019-1022.
8. O’Donnell, CP, Ayuse T, King ED, Schwartz AR, Smith PL, Robotham JL. Airway obstruction during sleep increases blood pressure without arousal. J Appl Physiol 1996; 80:773-781.
9. Shepard JW Jr. Gas exchange and hemodynamics during sleep. Med Clin North Am 1985; 69:1243-1263.
10. Kimoff RJ, Makino H, Horner RL, Kozar LF, Lue F, Slutsky AS, Phillipson EA. Canine model of obstructive sleep apnea: model description and preliminary application. J Appl Physiol 1994; 76:1810-1817.
11. Brooks D, Horner RL, Kozar LG, Render-Teixeir CL, Phillipson EA. Obstructive sleep apnea as a cause of systemic hypertension: evidence from a canine model. J Clin Invest 1997; 99:106-109.
12. Korner PI, White, SW. Circulatory control in hypoxia by the sympathetic nerves and adrenal medulla. J Physiol 1966; 184:272-290.
13. Johnson TS, Young JB, Landsberg L. Sympathoadrenal response to acute and chronic hypoxia in the rat. J Clin Invest 1983; 71:1263-1272.
14. Fletcher EC, Lesske J, Qian W, Miller CC, Unger T. Repetitive, episodic hypoxia causes diurnal elevation of systemic blood pressure in rats. Hypertension 1992; 19: 555-561.
15. Fletcher EC, Lesske J, Behm R, Miller CC, Unger T. Carotid chemoreceptors, systemic blood pressure, and chronic episodic hypoxia mimicking sleep apnea. J Appl Physiol 1992; 72:1978-1984.
16. Fletcher EC, Lesske J, Culman J, Miller CC, Unger T. Sympathetic denervation blocks blood pressure elevation episodic hypoxia. Hypertension 1992; 20:612-619.
17. Bao G, Fletcher EC. Mechanism of acute blood pressure elevation during episodic hypercapnic hypoxia in rats simulating sleep apnea. J Appl Physiol 1997; 82:10711078.
18. Fletcher EC, Bao G, Miller CC. Effect of recurrent episodic hypocapnic, eucapnic, and hypercapnic hypoxia on systemic blood pressure. J Appl Physiol 1995; 78:15161521.
19. Ringler J, Basner RC, Shannon R, Schwartzstein R, Manning H, Weinberger SE, Weiss JW. Hypoxemia alone does not explain blood pressure elevations after obstructive apneas. J Appl Physiol 1990; 69:2143-2148.
20. Ringler JE, Garpestad RC, Basner RC, Weiss JW. Systemic blood pressure elevation after airway occlusion during NREM sleep. Am J Respir Crit Care Med 1994; 150: 1062-1066.
21. Bao G, Metreveli N, Fletcher EC. Acute and chronic blood pressure response to recurrent acoustic arousal in rats. Am J Hypertens 1999; 12:504-510.
22. Bao G, Metreveli N, Li R, Taylor A, Fletcher EC. Blood pressure response to chronic episodic hypoxia: role of the sympathetic nervous system. J Appl Physiol 1997; 83: 95-101.
23. Floras JS, Aylward PE, Victor RG, Mark AL, Abboud FM. Epinephrine facilitates neurogenic vasoconstriction in humans. J Clin Invest 1988; 81:1265-1274.
24. Floras JS. Aylward PE. Mark AL, Abboud FM. Adrenalin facilitates neurogenic vasoconstriction in borderline hypertensive subjects. J Hypertens 1990; 8:443-448.
25. Loeffler JR, Stockigt JR, Ganong WF. Effect of alpha and beta adrenergic blocking agents on the increase in renin secretion produced by stimulation of renal nerves. Neuroendocrinology 1972; 10:129-138.
26. Blair ML, Hisa H, Sladek, CD, Radke KJ, Gengo FM. Dual adrenergic control of renin during non-hypotensive hemorrhage in conscious dogs. Am J Physiol 1991; 260:E910-E919.
27. Blair ML, Gengo FM. β-adrenergic control of renin in sodium-deprived conscious dogs: renal versus extrarrenal location. Can J Physiol Pharmacol 1995; 73:11981202.
28. Leuenberger U, Gleeson K, Wroblewski K, Prophet S, Zelis R, Zwillich C, Sinoway L. Norepinephrine clearance is increased during acute hypoxemia in humans. Am J Physiol 1991; 261:H1659-H1664.
29. Goldstein DS, Feuerstein G, Izzo JL Jr. Liquid chromatography for measuring norepinephrine and epinephrine in man. Life Sci 1981; 28:467-475.
30. Torda T, Culman J, Petrikova M. Distribution of phenylethanolamine-N-methyl-transferase in the rat heart: effect of 6-hydroxydopamine. Eur J Pharmacol 1987; 141:305-308.
31. Fluharty SJ, Vollmer RR, Meyers SA, McCann MJ, Zigmond MJ, Stricker EM. Recovery of chronotropic responsiveness after systemic 6-hydroxydopamine treatment: Studies in the pithed rat. J Pharm Exp Ther 1987; 243:415-423.
32. Nattie EE, D Bartlett Jr, Johnson K. Pulmonary hypertension and right ventricular hypertrophy caused by intermittent hypoxia and hypercapnia in the rat. Am Rev Respir Dis 1978; 118:653-658.
33. Ressl J, Urbanova D, Widimsky J. Reversibility of pulmonary hypertension and right ventricular hypertrophy induced by intermittent high altitude hypoxia in rats. Respiration 1974; 31:38-46.
34. Widimsky J, Urbanova D, Ressl J. Effect of intermittent altitude hypoxia on the myocardium and lesser circulation in the rat. Cardiovasc Res 1973; 7:798-808.
35. McGrath JJ, Prochazka J, Pelouch B, Ostadal B. Physiological response of rats to intermittent high altitude stress: effects of age. J Appl Physiol 1973; 34:289293.
36. Fletcher EC, Li R, Bao G. Renin activity and blood pressure in chronic episodic hypoxia (abstr). Hypertension 1999; 34:309-314.
37. Fletcher EC, Bao G. The effect of recurrent episodic eucapnic and hypocapnic hypoxia on systemic blood pressure in hypertension prone rats. J Appl Physiol 1996; 81:2088-2094.
38. Fregly MJ. Effect of chronic exposure to hypoxia on development and maintenance of renal hypertension in rats. Proc Soc Exp Biol Med 1970; 134:78-82.
39. Ou LC, Smith RP. Probable strain differences of rats in susceptibilities and cardiopulmonary responses to chronic hypoxia. Respir Physiol 1983; 53:367-377.
40. Luscher TF, Boulanger CM, Dohi Y, Yang Z. Endothelium-Derived contracting factors. Hypertension 1992; 19:117-130.
41. Folkow B. Physiological aspects of primary hypertension. Physiol Rev 1982; 62: 347-504.
42. Folkow B. Psychosocial and central nervous influences in primary hypertension. Circulation 1987; 76(suppl i):i10-i19.
43. Yamori Y, Ikeda K, Kulakowski EC, McCarty R, Lovenberg W. Enhanced sympathetic-adrenal medullary response to cold exposure in spontaneously hypertensive rats. J Hypertens 1985; 3:63-67.
44. Lawler JE, Barker GF, Hubbard JW, Allen MT. Conflict and tonic levels of BP in the genetically borderline hypertensive rat. Psychophysiology 1980; 17:363-370.
45. Lawler JE, Sanders BJ, Chen Y, Nagahama S, Oparil S. Hypertension from a high sodium diet in borderline hypertensive rat. Clin Exp Hypertens 1987; A9:1713-1731.
46. Hubbard JW, Cox RH, Sanders BJ, Lawler JE. Changes in cardiac output and vascular resistance during behavioral stress in the rat. Am J Physiol 1986; 251:R82-R90.
47. Wolinsky H. Response of the rat aortic media to hypertension. Circ Res 1976; 26: 507-512.
48. Mulvany JJ, Halpern W. Contractile properties of small arterial resistance vessels in spontaneously hypertensive and normotensive rats. Circ Res 1977; 41:19-26.
49. Pagnan A, Thiene G, Pessina AC, Dal Palu C. Serum lipoproteins and atherosclerosis in hypertensive broad breasted white turkeys. Artery 1980; 6:320-327.
50. Lombard J, Chenoweth JL, Stekiel WJ. Nonneural vascular smooth muscle tone in arterioles of the hamster. Hypertension 1984; 6:540-535.
51. Lokhandwala MF and Eikenburg DC. Presynaptic receptors and alteration in norepinephrine release in spontaneously hypertensive rat. Life Sci 1983; 33:1527-1542.
52. Pauletto P, Scannapieco G, Pessina AC. Sympathetic drive and vascular damage in hypertension and atherosclerosis. Hypertension 1991; 17(suppl III):III 75-III 81.
53. Spence JD. Effects of antihypertensive drugs on blood velocity: implications for prevention of cerebral vascular disease. Can J Neurol Sci 1977; 4:93-97.
54. Davies PF, Remuzzi A, Gordon EJ, Forbes DC, Gimbrone MA. Turbulent fluent shear stress induced vascular endothelial cell turnover in vitro. Cell Biol 1986; 83: 2114-2117.
55. Helin P, Lorenzen I, Garbarsch C, Matthiessen E. Arteriosclerosis in rabbit aorta induced by noradrenalin. Atherosclerosis 1970; 12:125-132.
56. Yamori Y, Tarazi RC, Oshima O. Effect of beta-receptor blocking agents on cardiovascular structural changes in spontaneous and noradrenaline-induced hypertension in rats. Clin Sci 1980; 59:457s-460s.
57. El Halawani ME, Weibel PE, Appel JR, Good AL. Catecholamine and monoamine-oxidase activity in turkeys with high or low blood pressure. Trans NY Acad Sci 1973; 35:463-470.
58. Blaes N, Bloissel JP. Growth-stimulating effect of catecholamines on rat aortic smooth muscle cells in culture. J Cell Physiol 1983; 116:167-171.