Prediction of Tablet Hardness and Porosity Using Near-Infrared Diffuse Reflectance Spectroscopy as a Nondestructive Method

Pharmaceutical Development and Technology

Volumn 8, Issue 4, 2003, Pages 357-366

  Donoso, M ^a   Kildsig, D O ^b   Ghaly, Evone S ^a  

^a UNIVERSITY OF PUERTO RICO   (Puerto Rico)

^b PURDUE UNIVERSITY   (United States)

Author keywords

Diffuse reflectance spectroscopy; Hardness; Near infrared spectroscopy; NIR; Porosity; Prediction; Theophylline; Validation

Indexed keywords

MICROCRYSTALLINE CELLULOSE; THEOPHYLLINE;

ANALYTIC METHOD; ARTICLE; DRUG DETERMINATION; DRUG FORMULATION; LINEAR REGRESSION ANALYSIS; NEAR INFRARED REFLECTANCE SPECTROSCOPY; POROSITY; PREDICTION; PRIORITY JOURNAL; TABLET COMPRESSION; TABLET HARDNESS; TABLET MANUFACTURE;

CELLULOSE; CHEMISTRY, PHARMACEUTICAL; HARDNESS TESTS; POROSITY; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; STEARIC ACIDS; TABLETS; THEOPHYLLINE;

EID: 0142062974     PISSN: 10837450     EISSN: None     Source Type: Journal    
DOI: 10.1081/PDT-120024689     Document Type: Article

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