Expression of lysostaphin in milk of transgenic mice affects the growth of neonates

Transgenic Research

Volumn 12, Issue 5, 2003, Pages 597-605

  Mitra, Abhijit ^a,c   Hruska, Kathleen S ^a   Wellnitz, Olga ^b   Kerr, David E ^b   Capuco, Anthony V ^a   Wall, Robert J ^a  

^a AGRICULTURAL RESEARCH SERVICE   (United States)

^b UNIVERSITY OF VERMONT   (United States)

^c INDIAN VETERINARY RESEARCH INSTITUTE   (India)

Author keywords

Lysostaphin; Mammary gland; Mastitis; Neonatal development

Indexed keywords

ANIMALS; ANIMALS, NEWBORN; ANTI-INFECTIVE AGENTS, LOCAL; FEMALE; LYSOSTAPHIN; MAMMARY GLANDS, ANIMAL; MICE; MICE, TRANSGENIC; MILK;

ANIMALIA; MUS MUSCULUS;

EID: 0142040179     PISSN: 09628819     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1025887101420     Document Type: Article

References (42)

1. Besnard N, Persuy MA, Stinnakre MG, Lepourry L, Da Silva JC, Goubin G et al. (2002) Targeted expression of the only zinc finger gene in transgenic mice is associated with impaired mammary development. Transgenic Res 11: 505-513.
2. Bramley AJ and Foster R (1990) Effects of lysostaphin on Staphylococcus aureus infections of the mouse mammary gland. Res Vet Sci 49: 120-121.
3. Brown MA, Nicolai H, Howe K, Katagiri T, Lalani E, Simpson KJ, et al. (2002) Expression of a truncated Brca1 protein delays lactational mammary development in transgenic mice. Transgenic Res 11: 467-478.
4. Burdon T, Wall RJ, Shamay A, Smith GH and Hennighausen L (1991) Over-expression of an endogenous milk protein gene in transgenic mice is associated with impaired mammary alveolar development and a milchlos phenotype. Mech Dev 36: 67-74.
5. Cavadini C, Hertel C and Hammes WP (1998) Application of lysostaphin-producing lactobacilli to control staphylococcal food poisoning in meat products. J Food Prot 61: 419-424.
6. Chomczynski P and Sacchi N (1987) Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 162: 156-159.
7. Clark AJ (1996) Genetic modification of milk proteins. Am J Clin Nutr 63: 633S-638S.
8. Dajcs JJ, Thibodeaux BA, Hume EB, Zheng X, Sloop GD and O'Callaghan RJ (2001) Lysostaphin is effective in treating methicillin-resistant Staphylococcus aureus endophthalmitis in the rabbit. Curr Eye Res 22: 451-457.
9. Hamosh M (1979) A review. Fat digestion in the newborn: role of lingual lipase and preduodenal digestion. Pediatr Res 13: 615-622.
10. Hathaway HJ and Shur BD (1996) Mammary gland morphogenesis is inhibited in transgenic mice that overexpress cell surface beta1,4-galactosyltransferase. Development 122: 2859-2872.
11. Heyman M, Crain-Denoyelle AM, Corthier G, Morgat JL and Desjeux JF (1986) Postnatal development of protein absorption in conventional and germ-free mice. Am J Physiol 251: G326-G331.
12. Howlett AR and Bissell MJ (1993) The influence of tissue microenvironment (stroma and extracellular matrix) on the development and function of mammary epithelium. Epithelial Cell Biol 2: 79-89.
13. Jara-Almonte M and White JM (1972) Milk production in laboratory mice. J Dairy Sci 55: 1502-1505.
14. Kerr DE, Plaut K, Bramley AJ, Williamson CM, Lax AJ, Moore K, et al. (2001) Lysostaphin expression in mammary glands confers protection against staphylococcal infection in transgenic mice. Nat Biotechnol 19: 66-70.
15. Lee SH and de Boer HA (1994) Production of biomedical proteins in the milk of transgenic dairy cows: the state of the art. J Control Release 29: 213-221.
16. Li M, Liu X, Robinson G, Bar-Peled U, Wagner KU, Young WS et al. (1997) Mammary-derived signals activate programmed cell death during the first stage of mammary gland involution. Proc Natl Acad Sci USA 94: 3425-3430.
17. Lonnerdal B (1996) Recombinant human milk proteins - an opportunity and a challenge. Am J Clin Nutr 63: 622S-626S.
18. Lucas A, Gibbs JA, Lyster RL and Baum JD (1978) Creamatocrit: simple clinical technique for estimating fat concentration and energy value of human milk. Br Med J 1: 1018-1020.
19. Lund LR, Bjorn SF, Sternlicht MD, Nielsen BS, Solberg H, Usher PA et al. (2000) Lactational competence and involution of the mouse mammary gland require plasminogen. Development 127: 4481-4492.
20. Maga EA and Murray JD (1995) Mammary gland expression of transgenes and the potential for altering the properties of milk. Biotechnology (NY) 13: 1452-1457.
21. Maga EA, Anderson GB, Huang MC and Murray JD (1994) Expression of human lysozyme mRNA in the mammary gland of transgenic mice. Transgenic Res 3: 36-42.
22. Maga EA, Anderson GB and Murray JD (1995) The effect of mammary gland expression of human lysozyme on the properties of milk from transgenic mice. J Dairy Sci 78: 2645-2652.
23. Marti A, Feng Z, Altermatt HJ and Jaggi R (1997) Milk accumulation triggers apoptosis of mammary epithelial cells. Eur J Cell Biol 73: 158-165.
24. McCullogh JS, Ratcliffe B, Mandir N, Carr KE and Goodlad RA (1998) Dietary fibre and intestinal microflora: effects on intestinal morphometry and crypt branching. Gut 42: 799-806.
25. Mochizuki S and Makita T (1998) Differences in intestinal length between specific-pathogen-free (SPF) and conventional swine. J Vet Med Sci 60: 545-548.
26. Nemir M, Bhattacharyya D, Li X, Singh K, Mukherjee AB and Mukherjee BB (2000) Targeted inhibition of osteopontin expression in the mammary gland causes abnormal morphogenesis and lactation deficiency. J Biol Chem 275: 969-976.
27. Oldham ER and Daley MJ (1991) Lysostaphin: use of a recombinant bactericidal enzyme as a mastitis therapeutic. J Dairy Sci 74: 4175-4182.
28. Park PW, Senior RM, Griffin GL, Broekelmann TJ, Mudd MS and Mecham RP (1995) Binding and degradation of elastin by the staphylolytic enzyme lysostaphin. Int J Biochem Cell Biol 27: 139-146.
29. Patron RL, Climo MW, Goldstein BP and Archer GL (1999) Lysostaphin treatment of experimental aortic valve endocarditis caused by a Staphylococcus aureus isolate with reduced susceptibility to vancomycin. Antimicrob Agents Chemother 43: 1754-1755.
30. Platenburg GJ, Kootwijk EP, Kooiman PM, Woloshuk SL, Nuijens JH, Krimpenfort PJ et al. (1994) Expression of human lactoferrin in milk of transgenic mice. Transgenic Res 3: 99-108.
31. Reiter B (1978) Review of the progress of dairy science: antimicrobial systems in milk. J Dairy Res 45: 131-147.
32. Rich CB, Carreras I, Lucey EC, Jaworski JA, Buczek-Thomas JA, Nugent MA et al. (2003) Transcriptional regulation of pulmonary elastin gene expression in elastase-induced injury. Am J Physiol Lung Cell Mol Physiol.
33. Schindler CA and Schuhardt VT (1964) Lysostaphin: a new bacteriolytic agent for the Staphylococcus. Proc Natl Acad Sci USA 51: 414-421.
34. Sordillo LM and Streicher KL (2002) Mammary gland immunity and mastitis susceptibility. J Mammary Gland Biol Neoplasia 7: 135-146.
35. Sutra L and Poutrel B (1994) Virulence factors involved in the pathogenesis of bovine intramammary infections due to Staphylococcus aureus. J Med Microbiol 40: 79-89.
36. Takahashi N, Eisenhuth G, Lee I, Schachtele C, Laible N and Binion S (1992) Nonspecific antibacterial factors in milk from cows immunized with human oral bacterial pathogens. J Dairy Sci 75: 1810-1820.
37. Teraguchi S, Ozawa K, Yasuda S, Shin K, Fukuwatari Y and Shimamura S (1994) The bacteriostatic effects of orally administered bovine lactoferrin on intestinal enterobacteriaceae of SPF mice fed bovine milk. Biosci Biotechnol Biochem 58: 482-487.
38. Teraguchi S, Shin K, Ogata T, Kingaku M, Kaino A, Miyauchi H et al. (1995a) Orally administered bovine lactoferrin inhibits bacterial translocation in mice fed bovine milk. Appl Environ Microbiol 61: 4131-4134.
39. Teraguchi S, Shin K, Ozawa K, Nakamura S, Fukuwatari Y, Tsuyuki S et al. (1995b) Bacteriostatic effect of orally administered bovine lactoferrin on proliferation of Clostridium species in the gut of mice fed bovine milk. Appl Environ Microbiol 61: 501-506.
40. Waage S, Mork T, Roros A, Aasland D, Hunshamar A and Odegaard SA (1999) Bacteria associated with clinical mastitis in dairy heifers. J Dairy Sci 82: 712-719.
41. Yang J, Ratovitski T, Brady JP, Solomon MB, Wells KD and Wall RJ (2001) Expression of myostatin pro domain results in muscular transgenic mice. Mol Reprod Dev 60: 351-361.
42. Yarus S, Rosen JM, Cole AM and Diamond G (1996) Production of active bovine tracheal antimicrobial peptide in milk of transgenic mice. Proc Natl Acad Sci USA 93: 14118-14121.