Interlaboratory ring test of time-resolved fluoroimmunoassays for zeranol and α-zearalenol and comparison with zeranol test kits

Food Additives and Contaminants

Volumn 20, Issue 9, 2003, Pages 804-812

  Cooper, K M ^a   Ribeiro, L ^d   Alves, P ^d   Vozikis, V ^c   Tsitsamis, S ^c   Alfredsson, G ^e   Lovgren T ^f   Tuomola, M ^f   Takalo, H ^g   Iitia, A ^g   Sterk, S S ^h   Blokland, M ^h   Kennedy, D Glenn ^b  

^a QUEEN'S UNIVERSITY BELFAST   (United Kingdom)

^b AGRI FOOD AND BIOSCIENCES INSTITUTE   (United Kingdom)

^c INSTITUTE OF TECHNOLOGY OF AGRICULTURAL PRODUCTS   (Greece)

^d Laboratorio Nacional de Investigacao Veterinaria   (Portugal)

^e NATIONAL FOOD ADMINISTRATION   (Sweden)

^f UNIVERSITY OF TURKU   (Finland)

^g Innotrac Diagnostics Oy   (Finland)

^h NATIONAL INSTITUTE FOR PUBLIC HEALTH AND THE ENVIRONMENT   (Netherlands)

Author keywords

Cross reactivity; Fusarium; Residues; Time resolved fluoroimmunoassay; Zearalenol; Zeranol

Indexed keywords

ALPHA ZEARALENOL; MYCOTOXIN; REAGENT; ZERANOL;

ACCURACY; ARTICLE; CATTLE; CONTROLLED STUDY; FLUOROIMMUNOASSAY; FOOD ANALYSIS; FOOD CONTAMINATION; FUSARIUM; IN VIVO STUDY; INTERMETHOD COMPARISON; LABORATORY TEST; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; SENSITIVITY AND SPECIFICITY; TIME; URINALYSIS;

ANIMALS; CATTLE; CROSS REACTIONS; ESTROGENS, NON-STEROIDAL; FALSE POSITIVE REACTIONS; FLUOROIMMUNOASSAY; FUSARIUM; MYCOTOXINS; REAGENT KITS, DIAGNOSTIC; SUBSTANCE ABUSE DETECTION; ZERANOL;

BOS TAURUS; BOVINAE; FUNGI; FUSARIUM;

EID: 0142030117     PISSN: 0265203X     EISSN: None     Source Type: Journal    
DOI: 10.1080/0265203031000156097     Document Type: Article

References (15)

1. Baxter, G. A., Elliott, C. T., Crooks, S. R. H., and McCaughey, W. J., 1996, Specificity enhancement of polyclonal antisera by the induction of tolerance to unwanted cross-reacting determinants. Food and Agricultural Immunology, 8, 85-95.
2. Blokland, M. H., Sterk, S. S., van Ginkel, L. A., Stephany, R. W., Launay, F. M., and Kennedy, D. G., 2003, Analysis of zeranol and metabolites in urine and meat. Manuscript in preparation.
3. Cooper, K. M., Tuomola, M., Lahdenperä, S., Lövgren, T., Elliott, C. T., and Kennedy, D. G., 2002, The development and validation of dry reagent time-resolved fluoroimmunoassays for zeranol and α-zearalenol to assist in distinguishing zeranol abuse from Fusarium spp. toxin contamination in bovine urine. Food Additives and Contaminants, 19, 1130-1137.
4. Council Directive 96/22/EEC, 1996, of 29 April 1996, Concerning the prohibition of use in stock farming of certain substances having a hormonal or thyrostatic action and of β-agonists, and repealing directives 81/602/EEC, 88/146/EEC and 88/299/EEC. Official Journal of the European Communities, L125, 3-9.
5. Council Directive 96/23/EEC, 1996, of 29 April 1996, On measures to monitor certain substances and residues thereof in live animals and animal products. Official Journal of the European Communities, L125, 10-32.
6. Crooks, S. R. H., Fodey, T. L., Gilmore, G. R., and Elliott, C. T., 1998, Rapid screening for monensin residues in poultry plasma by a dry reagent dissociation enhanced lanthanide fluoroimmunoassay. Analyst, 123, 2493-2496.
7. Crooks, S. R. H., Ross, P., Thompson, C. S., Haggan, S. A., and Elliott, C. T., 2000, Detection of unwanted residues of ivermectin in bovine milk by dissociation-enhanced lanthanide fluoroimmunoassay. Luminescence, 15, 371-376.
8. Elliott, C. T., Francis, K. S., and McCaughey, W. J., 1994, Investigation of dissociation enhanced lanthanide fluoroimmunoassay as an alternative screening test for veterinary drug residues. Analyst, 119, 2565-2569.
9. Elliott, C. T., Francis, K. S., Shortt, H. D., and McCaughey, W. J., 1995, Determination of the concentrations of the steroids estradiol, progesterone and testosterone in bovine sera - comparison of commercial dissociation enhanced lanthanide fluorescence immunoassay kits with conventional radio and enzyme immunoassays. Analyst, 120, 1827-1830.
10. Erasmuson, A. F., Scahill, B. G., and West, D. M., 1994, Natural zeranol (alpha-zearalanol) in the urine of pasture-fed animals. Journal of Agricultural and Food Chemistry, 42, 2721-2725.
11. Kennedy, D. G., Hewitt, S. A., McEvoy, J. D. G., Currie, J. W., Cannavan, A., Blanchflower, W. J., and Elliott, C. T., 1998, Zeranol is formed from Fusarium spp. toxins in cattle in vivo. Food Additives and Contaminants, 14, 393-400.
12. Kennedy, D. G., McEvoy, J. D. G., Blanchflower, W. J., Hewitt, S. A., Cannavan, A., McCaughey, W. J., and Elliott, C. T., 1995, Possible naturally occurring zeranol in bovine bile in Northern Ireland. Journal of Veterinary Medicine B, 42, 509-512.
13. Kleinova, M., Zöllner, P., Kahlbacher, H., Hochsteiner, W., and Lindner, W., 2002, Metabolic profiles of the mycotoxin zearalenone and of the growth promoter zeranol in urine, liver and muscle of heifers. Journal of Agricultural and Food Chemistry, 50, 4769-4776.
14. Lövgren, T., Meriö, L., Mitrunen, K., Mäkinen, M. -L., Mäkelä, M., Blomberg, K., Palenius, T., and Pettersson, K., 1996, One-step all-in-one dry reagent immunoassays with fluorescent europium chelate label and time-resolved fluorometry. Clinical Chemistry, 42, 1196-1201.
15. Tuomola, M., Cooper, K. M., Lahdenperä, S., Baxter, G. A., Kennedy, D. G., Elliott, C. T., and Lövgren, T., 2002, A specificity-enhanced time-resolved fluoroimmunoassay for zeranol employing the dry reagent all-in-one principle. Analyst, 127, 83-86.