Are Broad-Spectrum Sunscreens Necessary for Immunoprotection?

Journal of Investigative Dermatology

Volumn 121, Issue 4, 2003, Pages

  Young, Antony R ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN; SUNSCREEN;

CHROMATOPHORE; CONTACT ALLERGY; DENSITY; ERYTHEMA; HUMAN; IMMUNITY; IMMUNOSUPPRESSIVE TREATMENT; NONHUMAN; NOTE; PHOTODERMATOSIS; PRIORITY JOURNAL; SKIN ALLERGY; SKIN CARCINOMA; SKIN PROTECTION; STATISTICAL ANALYSIS; ULTRAVIOLET A RADIATION; ULTRAVIOLET B RADIATION; VOLUNTEER;

EID: 0141991219     PISSN: 0022202X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1523-1747.2003.12507.x     Document Type: Note

References (10)

1. Baron ED, Fourtanier A, Compan D, Medaisko C, Cooper KD, Stevens SR: High UVA protection affords greater immune protection confirming that UVA contributes to photoimmunosuppression in humans. J Invest Dermatol 121:869-875, 2003
2. IARC Handbooks of Cancer Prevention. Sunscreens vol 5. Lyon, WHO International Agency for Research on Cancer, 2001
3. Garssen J, de Gruijl F, Mol D, de Klerk A, Roholl P, van Lovern H: UVA exposure affects UVB and cis-urocanic acid-induced systemic suppression of immune responses in Listeria monocytogenes-infected Balb/c mice. Photochem Photobiol 73:432-438, 2001
4. Kelly DA, Seed PT, Young AR, Walker SL: A commercial sunscreen's protection against ultraviolet radiation induced immunosuppression is more than 50% lower than protection against sunburn in humans. J Invest Dermatol 120:65-71, 2003
5. Kuchel JM, Barnetson R StC, Halliday GM: Ultraviolet A augments solar-simulated ultraviolet radiation-induced local suppression of recall responses in humans. J Invest Dermatol 118:1032-1037, 2002
6. Moval D, Fourtanier AM: Broad-spectrum sunscreens provide better protection from the suppression of the elicitation phase of delayed-type hypersensitivity response in humans. J Invest Dermatol 117:1186-1192, 2001
7. Poon SC, Barnetson R StC, Halliday GM: Prevention of immunosuppression by sunscreens in humans is unrelated to protection from erythema and dependent on protection from ultraviolet A in the face of constant UVB protection. J Invest Dermatol 121:184-190, 2003
8. Reeve VE, Tyrell RM: Heme oxygenase induction mediates the photoimmunopro-tective activity of UVA radiation in the mouse. Proc Natl Acad Sci USA 96:9317-9321, 1999
9. van de Pas C, Seed P, Hawk J, Young AR, Walker SL: UVR-induced suppression of contact hypersensitivity responses in patients with polymorphic light eruption. J Invest Dermatol, in press
10. Wolf P, Hoffman C, Quehenberger F, Grinschgl S, Kerl H: Immune protection factors of chemical sunscreens measured in the local contact hypersensitivity model in humans. J Invest Dermatol, in press