Effect of recombinant granulocyte colony-stimulating factor on blood neutrophil concentrations among patients with "idiopathic neonatal neutropenia": Randomized, placebo-controlled trial

Journal of Perinatology

Volumn 23, Issue 6, 2003, Pages 493-497

  Juul, Sandra E ^a   Christensen, Robert D ^b  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF SOUTH FLORIDA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PLACEBO; RECOMBINANT GRANULOCYTE COLONY STIMULATING FACTOR;

ARTICLE; BIRTH WEIGHT; BONE MARROW CELL; CELL MOTILITY; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG RESPONSE; FEMALE; HOSPITAL ADMISSION; HOST RESISTANCE; HUMAN; IDIOPATHIC DISEASE; INFANT; LEUKOCYTE COUNT; MAJOR CLINICAL STUDY; MALE; NEUTROPENIA; NEWBORN DISEASE; NEWBORN INTENSIVE CARE; PROSPECTIVE STUDY; RANDOMIZED CONTROLLED TRIAL; TREATMENT OUTCOME;

FEMALE; GRANULOCYTE COLONY STIMULATING FACTOR, RECOMBINANT; HUMANS; INFANT, NEWBORN; INFANT, NEWBORN, DISEASES; INFANT, VERY LOW BIRTH WEIGHT; LEUKOCYTE COUNT; MALE; NEUTROPENIA; NEUTROPHILS; PROSPECTIVE STUDIES;

EID: 0141962515     PISSN: 07438346     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.jp.7210961     Document Type: Article

References (27)

1. Juul SE, Calhoun DA, Christensen RD. "Idiopathic neutropenia" in very low birthweight infants. Acta Paediatr 1998;87:963-8.
2. Omar SA, Salhadar A, Wooliever DE, Alsgaard PK. Late-onset neutropenia in very low birth weight infants. Pediatrics 2000;106E:55.
3. Calhoun DA, Christensen RD, Edstrom CS, et al. Consistent approaches to procedures and practices in neonatal hematology. Clin Perinatol 2000;27:733-53.
4. Bux J, Hofmann C, Welte K. Serum G-CSF levels are not increased in patients with antibody-induced neutropenia unless they are suffering from infectious diseases. Br J Haematol 1999;105:616-7.
5. Bux J, Stroncek D. Human neutrophil antigens. Transfusion 2002;42:1523.
6. Sola MC, Rimsza LM, Christensen RD. A bone marrow biopsy technique suitable for use in neonates. Br J Haematol 1999;107:458-60.
7. al-Mulla ZS, Christensen RD. Neutropenia in the neonate. Clin Perinatol 1995;22:711-39.
8. Welte K, Dale D. Pathophysiology and treatment of severe chronic neutropenia. Ann Hematol 1996;72:158-65.
9. Welte K, Boxer LA. Severe chronic neutropenia: pathophysiology and therapy. Semin Hematol 1997;34:267-78.
10. Zeidler C, Boxer L, Dale DC, Freedman MH, Kinsey S, Welte K. Management of Kostmann syndrome in the G-CSF era. Br J Haematol 2000;109:490-5.
11. Bonilla MA, Dale D, Zeidler C, et al. Long-term safety of treatment with recombinant human granulocyte colony- stimulating factor (r-metHuG-CSF) in patients with severe congenital neutropenias. Br J Haematol 1994;88:723-30.
12. Ades LC, Gedeon AK, Wilson MJ, et al. Barth syndrome: clinical features and confirmation of gene localization to distal Xq28. Am J Med Genet 1993;45:327-34.
13. Calhoun DA, Christensen RD. Recent advances in the pathogenesis and treatment of nonimmune neutropenias in the neonate. Curr Opin Hematol 1998;5:37-41.
14. Murray NA, Acolet D, Deane M, Price J, Roberts IA. Fetal marrow suppression after maternal chemotherapy for leukaemia. Arch Dis Child Fetal Neonatal Ed 1994;71:F209-10.
15. Morstyn G, Foote M, Nelson S. Clinical benefits of improving host defenses with rHuG-CSF. Ciba Found Symp 1997;204:78-85.
16. Gilmore MM, Stroncek DF, Korones DN. Treatment of alloimmune neonatal neutropenia with granulocyte colony-stimulating factor. J Pediatr 1994;125:948-51.
17. Rodwell RL, Gray PH, Taylor KM, Minchinton R. Granulocyte colony stimulating factor treatment for alloimmune neonatal neutropenia. Arch Dis Child Fetal Neonatal Ed 1996;75:F57-8.
18. Latini G, Del Vecchio A, Rosati E, Borzini P, Chirico G, Rondini G. Different responses to granulocyte colony-stimulating factor treatment in siblings with alloimmune neonatal neutropenia. Acta Paediatr 1999;88:1407-9.
19. Bux J, Behrens G, Jaeger G, Welte K. Diagnosis and clinical course of autoimmune neutropenia in infancy: analysis of 240 cases. Blood 1998;91:181-6.
20. Corbacioglu S, Bux J, Konig A, Gabrilove JL, Welte K, Bussel JB. Serum granulocyte colony-stimulating factor levels are not increased in patients with autoimmune neutropenia of infancy. J Pediatr 2000;137:96-9.
21. Kocherlakota P, La Gamma EF. Preliminary report: rhG-CSF may reduce the incidence of neonatal sepsis in prolonged preeclampsia-associated neutropenia. Pediatrics 1998;102:1107-11.
22. Makhlouf RA, Doron MW, Bose CL, Price WA, Stiles AD. Administration of granulocyte colony-stimulating factor to neutropenic low birth weight infants of mothers with preeclampsia. J Pediatr 1995;126:454-6.
23. Xanthou M. Leukocyte blood picture in ill newborn babies. Arch Dis Child 1972;47:741-6.
24. Manroe BL, Weinberg AG, Rosenfeld CR, Browne R. The neonatal blood count in health and disease. I. Reference values for neutrophilic cells. J Pediatr 1979;95:89-98.
25. Mouzinho A, Rosenfeld CR, Sanchez PJ, Risser R. Revised reference ranges for circulating neutrophils in very-low-birth-weight neonates. Pediatrics 1994;94:76-82.
26. Baley JE, Stork EK, Warkentin PI, Shurin SB. Neonatal neutropenia. Clinical manifestations, cause, and outcome. Am J Dis Child 1988;142:1161-6.
27. Bishop CR, Rothstein G, Ashenbrucker HE, Athens JW. Leukokinetic studies. XIV. Blood neutrophil kinetics in chronic steady-state neutropenia. J Clin Invest 1971;50:1678-89.