Dynorphin-A(1-17) decreases nitric oxide release and cytotoxicity induced with lipopolysaccharide plus interferon-γ in murine macrophage cell line J774

Biomedicine and Pharmacotherapy

Volumn 57, Issue 8, 2003, Pages 351-358

  Gabrilovac, Jelka ^a   Balog, Tihomir ^a   Andreis, Ana ^b  

^a RUDER BO KOVI INSTITUTE   (Croatia)

^b UNIVERSITY OF ZAGREB   (Croatia)

Author keywords

Cytotoxicity; Dynorphin A(1 17); Macrophage; Nitric oxide release; Opioid receptor

Indexed keywords

BACTERIUM LIPOPOLYSACCHARIDE; DYNORPHIN A; DYNORPHIN[1-13]; GAMMA INTERFERON; KAPPA OPIATE RECEPTOR; KAPPA OPIATE RECEPTOR ANTAGONIST; NITRIC OXIDE; NORBINALTORPHIMINE; OPIATE PEPTIDE;

ANIMAL CELL; ARTICLE; BIODEGRADATION; CELL ACTIVATION; CELL PROTECTION; CONTROLLED STUDY; CYTOTOXICITY; INFLAMMATION; MACROPHAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL;

EID: 0141961782     PISSN: 07533322     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0753-3322(03)00050-7     Document Type: Article

References (27)

1. Alicea C., Belkowski S., Eisenstein T.K., Adler M.W., Rogers T.J. Inhibition of primary murine macrophage cytokine production in vitro following treatment with the k-opioid agonist U50,488H. J Neuroimmunol. 64:1996;83-90.
2. 3H] thymidine incorporation into DNA: evidence for the involvement of Pertussis toxin-sensitive G protein-coupled phosphoinositide turnover. J Neurochem. 60:1993;1505-1511.
3. Belkowski S.M., Alicea C., Eisenstein T.K., Adler M.W., Rogers T.J. Inhibition of interleukin-1 and tumor necrosis factor-α synthesis following treatment of macrophages with kappa opioid agonist U50,488H. J Pharmacol Exp Ther. 273:1995;1491-1496.
4. Billiar T.R. Nitric oxide novel biology with clinical relevance. Ann Surg. 221:1995;339-349.
5. Cabot P.J., Carter L., Schaefer M., Stein C. Methionin-enkephalin- and dynorphin-A-release from immune cells and control of inflammatory pain. Pain. 93:2001;207-212.
6. Chao C.C., Hu S., Molitor T.W., Shaskan E.G., Peterson P.K. Activated microglia mediate neuronal cell injury via nitric oxide mechanism. J Immunol. 149:1992;2736-2741.
7. Chao C.C., Gekker G., Hu S., Sheng W.S., Portoghese P.S., Petterson P.K. Upregulation of HIV-1 expression in cocultures of chronically infected promonocytes and human brain cells by dynorphin. Biochem Pharmacol. 50:1995;715-722.
8. (1-13) peptides in human blood ex vivo. Peptides. 17:1996;983-990.
9. Eason S., Martin W. Involvement of tyrosine kinase and protein kinase C in the induction of nitric oxide synthase by lipopolysaccharide and interferon-γ in J774 macrophages. Arch Int Pharmacodyn. 330:1995;225-240.
10. Efanov A.M., Koshkin A.A., Sazanov L.A., Borodulina O.I., Varfolomeev S.D., Zaitsev S.V. Inhibition of the respiratory burst in mouse macrophages by ultra-low doses of an opioid peptide is consistent with a possible adaptation mechanism. FEBS Lett. 355:1994;114-116.
11. Eisenstein T.K., Hillburger M.E. Opioid modulation of immune responses: effects on phagocyte and lymphoid cell populations. J Neuroimmunol. 83:1998;36-44.
12. Foster J.S., Moore R.N. Dynorphin and related opioid peptides enhance tumoricidal activity mediated by murine peritoneal macrophages. Leukocyte Biol. 42:1987;171-174.
13. Gorodinsky A., Barg J., Belcheva M.M., Levy R., McHale R.J., Vogel Z., et al. Dynorphins modulate DNA synthesis in foetal brain cell aggregates. J Neurochem. 65:1995;1481-1486.
14. 15N)nitrate in biological fluids. Anal Biochem. 126:1982;131-138.
15. Guan L.M., Eisenstein T.K., Adler M.W., Rogers T.J. Inhibition of T cell superantigen responses following treatment with the k-opioid agonist U-50,488H. J Neuroimmunol. 75:1997;163-168.
16. Hagi K., Uno K., Inaba K., Muramatsu S. Augmenting effect of opioid peptides on murine macrophage activation. J Neuroimmunol. 50:1994;71-76.
17. Ignatowski T.A., Bidlack J.M. Differential k-opioid receptor expression on mouse lymphocytes at varying stages of maturation and on mouse macrophages after selective elicitation. J Pharmacol Exp Ther. 290:1999;863-870.
18. Morgan E.L. Regulation of human B-lymphocyte activation by opioid peptide hormones: Inhibition of IgG production by opioid receptor class(m-, k-, and d-) selective agonists. J Neuroimmunol. 65:1996;21-30.
19. Mosmann T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Methods. 65:1983;55-63.
20. Kong L.-Y., McMillian M.K., Hudson P.M., Jin L., Hong J.-S. Inhibition of lipopolysaccharide-induced nitric oxide and cytokine production by ultralow concentrations of dynorphins in mixed glia cultures. J Pharmacol Exp Ther. 280:1997;61-66.
21. Kong L.-Y., Jeohn G.-H., Hudson P.M., Du L., Liu B., Hong J.-S. Reduction of lipopolysaccharide-induced neurotoxicity in mouse mixed cortical neuron/glia cultures by ultralow concentrations of dynorphins. J Biomed Sci. 7:2000;241-247.
22. Kowalski J. Augmenting effect of opioids on nitrite production by stimulated murine macrophages. Neuropeptides. 32:1998;287-291.
23. Sarih M., Souvannavong V., Adam A. Nitric oxide synthase induces macrophage death by apoptosis. Biochem Biophys Res Commun. 191:1993;503-508.
24. Szabo I., Rojavin M., Bussiere J.L., Eisenstein T.K., Adler M.W., Rogers T.J. Suppression of peritoneal macrophages phagocytosis of Candida albicans by opioids. J Pharmacol Exp Ther. 267:1993;703-706.
25. Tosk J.M., Grim J.R., Kinback K.M., Sale E.J., Bozzetti L.P., Will A.D. Modulation of chemiluminiscence in a murine macrophage cell line by neuroendocrine hormones. Int J Immunopharmacol. 15:1993;615-620.
26. Vujić V., Stanojević S., Dimitrijević M. The effect of opioid peptides on superoxide anion production in rat peritoneal macrophages stimulated with zymosan: involvement of m, d and k opioid receptors. Acta Veterinaria. 52:2002;69-78.
27. Woo S.K., Tulunay F.C., Loh H.H., Lee N.M. Effect of dynorphin1-13 and related peptides on respiratory rate and morphine-induced respiratory rate depression. Eur J Pharmacol. 96:1983;117-122.