CoMFA Modeling of Enzyme Kinetics: Km Values for Sulfation of Diverse Phenolic Substrates by Human Catecholamine Sulfotransferase SULT1A3

Journal of Chemical Information and Computer Sciences

Volumn 43, Issue 5, 2003, Pages 1563-1569

  Sipilä, Julius ^a   Hood, Alan M ^b,c   Coughtrie, Michael W H ^b   Taskinen, Jyrki ^a  

^a UNIVERSITY OF HELSINKI   (Finland)

^b UNIVERSITY OF DUNDEE   (United Kingdom)

^c Burdock Group   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ENZYME KINETICS; MOLECULAR DYNAMICS; MOLECULAR ORIENTATION; MOLECULAR STRUCTURE; PHENOLS; SULFUR COMPOUNDS;

SULFATION;

BIOCHEMISTRY;

MONOAMINE SULFATING PHENOL SULFOTRANSFERASE; MONOAMINE-SULFATING PHENOL SULFOTRANSFERASE; PHENOL DERIVATIVE; SULFATE; SULFOTRANSFERASE;

ARTICLE; BINDING SITE; BIOLOGICAL MODEL; CHEMICAL STRUCTURE; CHEMISTRY; COMPARATIVE STUDY; ELECTRICITY; ENZYME SPECIFICITY; HUMAN; HYDROPHOBICITY; KINETICS; METABOLISM; QUANTITATIVE STRUCTURE ACTIVITY RELATION;

BINDING SITES; ELECTROSTATICS; HUMANS; HYDROPHOBICITY; KINETICS; MODELS, BIOLOGICAL; MODELS, MOLECULAR; MOLECULAR STRUCTURE; PHENOLS; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY; SULFATES; SULFOTRANSFERASES;

EID: 0141959679     PISSN: 00952338     EISSN: None     Source Type: Journal    
DOI: 10.1021/ci034089e     Document Type: Article

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