Understanding the antitumor activity of novel hydroxysemicarbazide derivatives as ribonucleotide reductase inhibitors using CoMFA and CoMSIA

Journal of Medicinal Chemistry

Volumn 46, Issue 21, 2003, Pages 4419-4427

  Raichurkar, Anand V ^a   Kulkarni, Vithal M ^a,b  

^a UNIVERSITY OF MUMBAI   (India)

^b BHARATI VIDYAPEETH DEEMED UNIVERSITY   (India)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; ENZYME INHIBITOR; HYDROXYSEMICARBAZIDE DERIVATIVE; RIBONUCLEOTIDE REDUCTASE; RIBONUCLEOTIDE REDUCTASE INHIBITOR; SCHIFF BASE; UNCLASSIFIED DRUG;

ANALYTIC METHOD; ANTINEOPLASTIC ACTIVITY; ARTICLE; DRUG MECHANISM; LIPOPHILICITY; MOLECULAR MODEL; QUANTITATIVE STRUCTURE ACTIVITY RELATION;

ALGORITHMS; ANIMALS; ANTINEOPLASTIC AGENTS; ENZYME INHIBITORS; LEUKEMIA L1210; MODELS, MOLECULAR; RIBONUCLEOTIDE REDUCTASES; SEMICARBAZIDES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0141958102     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm030016a     Document Type: Article

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