New N6- or N(9)-hydroxyalkyl substituted 8-azaadenines or adenines as effective A1 adenosine receptor ligands

European Journal of Medicinal Chemistry

Volumn 38, Issue 9, 2003, Pages 801-810

  Biagi, Giuliana ^a   Giorgi, Irene ^a   Leonardi, Michele ^a   Livi, Oreste ^a   Pacchini, Federica ^a   Scartoni, Valerio ^a   Costa, Barbara ^b   Lucacchini, Antonio ^b  

^a UNIVERSITY OF PISA   (Italy)

^b Universitadi Pisa   (Italy)

Author keywords

2 phenyl 9 (2 hydroxy 3 alkyl) 8 azaadenines; 2 phenyl 9 (2 hydroxy 3 alkyl)adenines; A1 adenosine receptor ligands; N6 hydroxyalkyl 2 phenyl 9 benzyl 8 azaadenines

Indexed keywords

2 PHENYL 9 BENZYL 8 AZAHYPOXANTHINE; 5 AMINO 4,6 DICHLORO 2 PHENYLPYRIMIDINE; 5 AMINO 6 CHLORO 4 (2 HYDROXY 3 HEPTYL) 2 PHENYLPYRIMIDINE; 5 AMINO 6 CHLORO 4 (2 HYDROXY 3 PENTYL) 2 PHENYLPYRIMIDINE; 5 AMINO 6 CHLORO 4 (2 HYDROXY 3 PROPYL) 2 PHENYLPYRIMIDINE; 6 CHLORO 2 PHENYL 9 BENZYL 8 AZAADENINE; 6 CHLORO 9 (2 HYDROXY 3 HEPTYL) 2 PHENYL 8 AZAPURINE; 6 CHLORO 9 (2 HYDROXY 3 HEXYL) 2 PHENYLPURINE; 6 CHLORO 9 (2 HYDROXY 3 PENTYL) 2 PHENYL 8 AZAPURINE; 6 CHLORO 9 (2 HYDROXY 3 PENTYL) 2 PHENYLPURINE; 6 CHLORO 9 (2 HYDROXY 3 PROPYL) 2 PHENYL 8 AZAPURINE; 6 CHLORO 9 (2 HYDROXY 3 PROPYL) 2 PHENYLPURINE; ADENINE DERIVATIVE; ADENOSINE A1 RECEPTOR; PYRIMIDINE DERIVATIVE; UNCLASSIFIED DRUG; XANTHINE DERIVATIVE; ADENINE; DRUG DERIVATIVE; HETEROCYCLIC COMPOUND; LIGAND; WATER;

ARTICLE; BIOASSAY; DRUG SYNTHESIS; LIPOPHILICITY; RECEPTOR AFFINITY; SOLUBILITY; ANIMAL; BRAIN CORTEX; CATTLE; CHEMICAL STRUCTURE; CHEMISTRY; METABOLISM; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

ADENINE; ANIMALS; AZA COMPOUNDS; CATTLE; CEREBRAL CORTEX; LIGANDS; MOLECULAR STRUCTURE; RECEPTOR, ADENOSINE A1; STRUCTURE-ACTIVITY RELATIONSHIP; WATER;

EID: 0141953264     PISSN: 02235234     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0223-5234(03)00147-8     Document Type: Article

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