Platelet functional defects in women with unexplained menorrhagia

Journal of Thrombosis and Haemostasis

Volumn 1, Issue 3, 2003, Pages 477-484

  Philipp, C S ^a   Dilley, A ^b   Miller, C H ^b   Evatt, B ^b   Baranwal, A ^a   Schwartz, R ^a   Bachmann, G ^a   Saidi, P ^a  

^a ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

^b CENTERS FOR DISEASE CONTROL AND PREVENTION   (United States)

Author keywords

Bleeding disorders; Menorrhagia; Platelet dysfunction

Indexed keywords

ADRENALIN; BLOOD CLOTTING FACTOR; RISTOCETIN;

ADOLESCENT; ADULT; ARTICLE; BLOOD CLOTTING PARAMETERS; BLOOD CLOTTING TEST; DRUG EFFECT; FEMALE; HUMAN; MENORRHAGIA; MIDDLE AGED; PREVALENCE; RACE; THROMBOCYTE AGGREGATION; THROMBOCYTE DISORDER; VON WILLEBRAND DISEASE;

ADOLESCENT; ADULT; BLOOD COAGULATION FACTORS; BLOOD COAGULATION TESTS; BLOOD PLATELET DISORDERS; CONTINENTAL POPULATION GROUPS; EPINEPHRINE; FEMALE; HUMANS; MENORRHAGIA; MIDDLE AGED; PLATELET AGGREGATION; PLATELET FUNCTION TESTS; PREVALENCE; RISTOCETIN; VON WILLEBRAND DISEASE;

EID: 0141946145     PISSN: 15387933     EISSN: 15387836     Source Type: Journal    
DOI: 10.1046/j.1538-7836.2003.00061.x     Document Type: Article

References (32)

1. Lepine L, Hillis S, Marchbanks P et al. Hysterectomy surveillance (United States 1980-93. MMWR 1997; 46 (SS-4): 1-15.
2. Carlson K, Nichols D, Schiff I. Current concepts: indications for hysterectomy. NEJM 1993; 328: 856-60.
3. Lee NC, Dicker RC, Rubin GL, Ory HW. Confirmation of the preoperative diagnoses for hysterectomy. Am J Obstet Gynecol 1985; 152: 803-8.
4. Wingo P, Huezo C, Rubin G, Ory H, Peterson H. The mortality risk associated with hysterectomy. Am J Obstet Gynecol 1985; 152: 803-8.
5. Kadir RA, Economides DL, Sabin CA, Owens D, Lee CA. Frequency of inherited bleeding disorders in women with menorrhagia. Lancet 1998; 351: 485-9.
6. Edlund M, Blomback M, von Schoultz B, Andersson O. On the value of menorrhagia as a predictor for coagulation disorders. Am J Hematol 1996; 53: 234-8.
7. Dilley A, Drews C, Miller C et al. von Willebrand disease and other inherited bleeding disorders in women with diagnosed menorrhagia. Obst Gynecol 2001; 97: 630-6.
8. Feinman RD, Lubowsky J, Charo I, Zabinski MP. The lumi-aggregometer: a new instrument for simultaneous measurement of secretion and aggregation by platelets. J Lab Clin Med 1977; 90: 125-9.
9. Machin SJ, Preston E. Guidelines on platelet function testing. J Clin Pathol 1988; 41: 1322-30.
10. Miller CH, Dilley A, Richardson L, Hooper WC, Evatt BL. Population differences in von Willebrand factor levels affect the diagnosis of von Willebrand disease in African-American women. Am J Hematol 2001; 67: 125-9.
11. Higham JM, O'Brien PMS, Shaw RW. Assessment of menstrual blood loss using a pictorial chart. Br J Obst Gynecol 1990; 97: 734-9.
12. Janssen CAH, Scholten PC, Heintz APM. A simple visual assessment technique to discriminate between menorrhagia and normal menstrual blood loss. Obstet Gynecol 1995; 85: 977-82.
13. Harker LA, Slichter SJ. The bleeding time as a screening test for evaluation of platelet function. N Eng J Med 1972; 287: 155-9.
14. Duke WW. The relation of blood platelets to hemorrhagic disease: description of a method for determining the bleeding time and coagulation time and report of three cases of hemorrhagic disease relieved by transfusion. JAMA 1910; 55: 1185-92.
15. Fernandez F, Goudable C, Sie P et al. Low hematocrit and prolonged bleeding time in uremic patients: effects of red blood cell transfusions. Br J Haematol 1985; 59: 139-48.
16. Small M, Lowe GDO, Cameron E, Forbes CD. Contribution of the hematocrit to the bleeding time. Haemostasis 1983; 13: 379-84.
17. Buchanan GR, Holtkamp CA, Levy EN. Racial differences in ristocetininduced platelet aggregation. Br J Haematol 1981; 49: 455-64.
18. Mackie I, Bull H, Kennedy J, Brozovic M. Ristocetin-induced platelet agglutination in Afro-Caribbean and Caucasian people. Br J Haematol 1982; 50: 171-3.
19. Rao GH, White JG. Epinephrine and platelet function. J Lab Clin Med 1997; 130: 238-9.
20. Scrutton MC, Clare KA, Hutton RA, Bruckdorfer KR. Depressed responsiveness to adrenaline in platelets from apparently normal human donors: a familial trait. Br J Haematol 1981; 49: 303-14.
21. Kambayashi J, Shinoki N, Nakamura T et al. Prevalence of impaired responsiveness to epinephrine in platelets among Japanese. Thromb Res 1996; 81: 85-90.
22. Tamponi G, Pannocchia A, Arduino C et al. Congenital deficiency of alpha-2-adrenoceptors on human platelets: description of two cases. Thromb Haemost 1987; 58: 1012-6.
23. Rao AK, Willis J, Kowalska MA, Wachtfogel YT, Colman RW. Differential requirements for platelet aggregation andinhibition of adenylate cyclase by epinephrine. Studies of a familial platelet alpha2-adrenergic receptor defect. Blood 1988; 71: 494-501.
24. Lalau Keraly C, Kinlough-Rathbone RL, Packham MA, Suzuki H, Mustard JF. Conditions affecting the responses of human platelets to epinephrine. Thromb Haemost 1988; 60: 209-16.
25. Shattil SJ, Budzynski A, Scrutton MC. Epinephrine induces platelet fibrinogen receptor expression, fibrinogen binding, and aggregation in whole blood in the absence of other excitatory agonists. Blood 1989; 73: 150-8.
26. Blomback M, Eneroth P, Landgren BM, Lagerstrom M, Anderson O. On the Intraindividual and gender variability of hemostatic components. Thromb Haemost 1992; 67: 70-5.
27. Mandalaki T, Louizou C, Dimitriadou C, Symeonidis P. Variations in factor VIII during the menstrual cycle in normal women. NEJM 1980; 302: 1093.
28. Kadir RA, Economides DL, Sabin CA, Owens D, Lee CA. Variations in coagulation factors in women: effects of age, ethnicity, menstrual cycle and combined oral contraceptives. Thromb Haemost 1999; 82: 1456-61.
29. Kouides P, Phatak P, Sham RL et al. Adjusting the reference range of von Willebrand factor levels and factor VIIIc level in relation to the menstrual cycle [abstract]. Blood 1997; 90: 32a.
30. Miller CH, Dilley AB, Drews C, Richardson L, Evatt B. Changes in von Willebrand factor and factor VIII levels during the menstrual cycle. Thromb Haemost 2002; 87: 1082-3.
31. The MEDSTAT Group. MEDSTAT Data Base. The MEDSTAT Group, Ann Arbor, MI. Accessed 2000.
32. Rees M. Menorrhagia. BMJ 1987; 294: 759-62.