Inhibition of hemorrhagic and edematogenic activities of snake venoms by a broad-spectrum protease inhibitor, murinoglobulin; the effect on venoms from five different genera in Viperidae family

Toxicon

Volumn 42, Issue 2, 2003, Pages 173-181

  Filho, Wilker Ribeiro ^a   Sugiki, Masahiko ^a   Yoshida, Etsuo ^a   Maruyama, Masugi ^a  

^a UNIVERSITY OF MIYAZAKI   (Japan)

Author keywords

Edema; Hemorrhage; Murinoglobulin; Protease inhibitor; Snake venom

Indexed keywords

ALPHA 2 MACROGLOBULIN; BATROXOBIN; GELATINASE; MURINOGLOBULIN; PROTEINASE INHIBITOR; SNAKE VENOM; UNCLASSIFIED DRUG; SERUM GLOBULIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLEEDING; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; DRUG EFFECT; DRUG POTENCY; EDEMA; ENVENOMATION; ENZYME ACTIVITY; FIBRINOLYSIS; INCUBATION TIME; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEINASE INHIBITION; RAT; SNAKE; STATISTICAL SIGNIFICANCE; SYMPTOM; ANIMAL; BLOOD CLOTTING; CHEMICALLY INDUCED DISORDER; CLASSIFICATION; DRUG ANTAGONISM; INSTITUTE FOR CANCER RESEARCH MOUSE; ISOLATION AND PURIFICATION; METABOLISM; PATHOLOGY; SKIN; WISTAR RAT;

BOTHROPS; BOTHROPS JARARACA; CROTALUS; CROTALUS ATROX; ECHIS; ECHIS CARINATUS SOCHUREKI; LACHESIS MUTA; LACHESIS MUTA MUTA; SERPENTES; TRIMERESURUS; TRIMERESURUS FLAVOVIRIDIS; VIPERIDAE;

ANIMALS; BLOOD COAGULATION; CROTALID VENOMS; EDEMA; FIBRINOLYSIS; GELATINASES; HEMORRHAGE; MALE; MICE; MICE, INBRED ICR; PROTEASE INHIBITORS; RATS; RATS, WISTAR; SERUM GLOBULINS; SKIN; VIPERIDAE;

EID: 0141940654     PISSN: 00410101     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0041-0101(03)00130-2     Document Type: Article

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