Detection of hepatic VX2 tumors in rabbits: Comparison of conventional US and phase-inversion harmonic US during the liver-specific late phase of contrast enhancement

Korean Journal of Radiology

Volumn 4, Issue 2, 2003, Pages 124-129

  Lee, Jeong Min ^a,b,c   Youk, Ji Hyun ^a   Lee, Young Hwan ^a   Kim, Young Kon ^a   Kim, Chong Soo ^a   Li, Chun Ai ^a  

^a Chonbuk National University Medical School   (South Korea)

^b Seoul National University College of Medicine   (South Korea)

^c Seoul National University Hospital   (South Korea)

Author keywords

Animals, liver neoplasms; Liver neoplasms, US; Ultrasound (US), contrast media; Ultrasound (US), harmonic study

Indexed keywords

ANIMAL TISSUE; ARTICLE; B SCAN; BOLUS INJECTION; CONTROLLED STUDY; ECHOGRAPHY; IMAGING SYSTEM; INTERMETHOD COMPARISON; LIVER PARENCHYMA; LIVER TUMOR; NONHUMAN; PATHOLOGICAL ANATOMY; RABBIT; TUMOR VOLUME; ULTRASOUND; ANIMAL; CANCER TRANSPLANTATION; MALE; METHODOLOGY;

CONTRAST MEDIUM; DIAGNOSTIC AGENT; POLYSACCHARIDE; SHU 508;

ANIMALS; CONTRAST MEDIA; LIVER NEOPLASMS, EXPERIMENTAL; MALE; NEOPLASM TRANSPLANTATION; POLYSACCHARIDES; RABBITS; ULTRASONOGRAPHY;

EID: 0141939630     PISSN: 12296929     EISSN: None     Source Type: Journal    
DOI: 10.3348/kjr.2003.4.2.124     Document Type: Article

References (25)

1. Bluemke DA, Paulson EK, Choti MA, DeSena S, Calvien PA. Detection of hepatic lesions in candidates for surgery. AJR Am J Roentgenol 2000;175:1653-1658
2. Alderson PO, Adams DF, McNeil BJ, et al. Computed tomography, ultrasound, and scintigraphy of the liver in patients with colon or breast carcinoma: a prospective comparison. Radiology 1983;149:225-230
3. Soyer PH, Levesque M, Elias D, Zeitoun G, Roche A. Detection of liver metastases from colorectal cancer: comparison of intraoperative ultrasound and CT during arterial portography. Radiology 1992;183:541-544
4. Wernecke K, Rummeny E, Bongartz G, et al. Detection of hepatic masses in patients with carcinoma: comparative sensitivities of sonography, CT, and MR imaging. AJR Am J Roentgenol 1991;157:731-739
5. Clarke MP, Kane RA, Steele G Jr, et al. Prospective comparison of preoperative imaging and intraoperative ultrasonography in the detection of liver tumors. Surgery 1989;106:849-855
6. Ohlsson B, Tranberg KG, Lundstedt C, Ekberg H, Hederstrom E. Detection of hepatic metastases in colorectal cancer: a prospective study of laboratory and imaging methods. Eur J Surg 1993;159:275-281
7. Ferrucci JT. Liver tumor imaging: current concepts. AJR Am J Roentgenol 1990;155:473-484
8. Burns PN, Wilson SR, Simpson DH. Pulse-inversion imaging of liver blood flow: improved method for characterizing focal masses with microbubble contrast. Invest Radiol 2000;35:58-71
9. Wilson SR, Burns PN, Muradali D, Wilson JA, Lai X. Harmonic hepatic US with microbubble contrast agent: initial experience showing improved characterization of hemangioma, hepatocellular carcinoma, and metastases. Radiology 2000;215:153-161
10. Blomley MJK, Albrecht T, Cosgrove D, Jayaram V, Butler-Barnes J, Eckersley R. Stimulated acoustic emission in liver parenchyma with Levovist (letter). Lancet 1998;351:568
11. Blomley MJK, Albrecht T, Cosgrove DO, et al. The use of stimulated acoustic emission to image a late liver-specific phase of Levovist: an investigation in normal volunteers and in patients with and without liver disease. Ultrasound Med Biol 1999;25: 1341-1352
12. Blomley MJK, Albrecht T, Cosgrove DO, et al. Improved imaging of liver metastases with stimulated acoustic emission in the late phase of enhancement with the US contrast agent SHU 508A: early experience. Radiology 1999;210:409-416
13. Forsberg F, Liu JB, Merton DA, Rawool NM, Johnson DK, Goldberg BB. Gray-scale second harmonic imaging of acoustic emission signals improves detection of liver tumors in rabbits. J Ultrasound Med 2000;19:557-563
14. Forsberg F, Piccoli CW, Rawool NM, Merton DA, Mitchell DG, Goldberg BB. Hepatic tumor detection: MR imaging and conventional US versus pulse-inversion harmonic US of NC100100 during its reticuloendothelial system-specific phase. Radiology 2002;222:824-829
15. Albrecht T, Hoffmann CW, Schettler S, et al. B-mode enhancement at phase-inversion US with air-based microbubble contrast agent: initial experience in humans. Radiology 2000;216:273-278
16. Albrecht T, Hoffmann CW, Schmitz SA, et al. Phase-inversion sonography during the liver-specific late phase of contrast enhancement: improved detection of liver metastases. AJR Am J Roentgenol 2001;176:1191-1198
17. Lang TM, Secic M. How to report statistics in medicine: annotated guidelines for authors, editors, and reviewers, 1st ed. Philadelphia: ACP, 2000:127-132
18. Finlay IG, McArdle CS. Effect of occult hepatic metastases on survival after curative resection for colorectal carcinoma. Gastroenterology 1983;85:596-599
19. Hughes KS, Sugarbaker PH. Treatment of metastatic liver tumors. In: Rosenberg SA, ed. Surgical cure of metastatic cancer. Philadelphia: Lippincott, 1987:125-164
20. Bauer A, Schlief R, Zomack M, Urbank A, Niendorf HP. Acoustically stimulated microbubbles in diagnostic ultrasound: properties and implications for diagnostic use. In: Nanda N, Schlief R, Goldberg BB, eds. Advances in echo imaging using contrast enhancement, 2nd ed. London: Kluwer, 1997:669-684
21. Simpson DH, Chin CT, Burns PN. Pulse-inversion Doppler: a new method for detecting nonlinear echoes from microbubble contrast agents. IEEE Trans Ultrason Ferroelec Freq Contr 1999;46:372-382
22. Forsberg F, Liu JB, Chiou HJ, Rawool NM, Parker L, Goldberg BB. Comparison of fundamental and wideband harmonic contrast imaging of liver tumors. Ultrasonics 2000;38:110-113
23. Simpson DH, Burns PN. Pulse-inversion Doppler: a new method for detecting nonlinear echoes from microbubble contrast agents. IEEE Ultrasonic Symposium 1997;1597-1600
24. Quaia E, Blomley MJK, Patel S, et al. Initial observations on the effect of irradiation on the liver-specific uptake of Levovist. Eur J Radiol 2002;41:192-199
25. Mitsuzaki K, Yamashita Y, Ogata I, et al. Multiple-phase helical CT of the liver for detecting small hepatomas in patients with liver cirrhosis: contrast-injection protocol and optimal timing. AJR Am J Roentgenol 1996;167:753-757