Pharmcological effects of the Allium victorialis var. platyphyllum extracts on the rats induced by streptozotocin, poloxamer-407, CCl4 and D-galactosamine

Korean Journal of Pharmacognosy

Volumn 34, Issue 3, 2003, Pages 250-255

  Choi, Jongwon ^a   Lee, Kyung Tae ^a   Kim, Won Bae ^a   Park, Kwang Gyun ^a   Jung, Hyun Ju ^a   Park, Hee Juhn ^a  

^a NONE

Author keywords

Allium victorialis var. platyphyllum; Antihepatotoxic; Hypoglycemic; Hypolipidemic; Liliaceae

Indexed keywords

ALLIUM VICTORIALIS EXTRACT; CARBON TETRACHLORIDE; CHOLESTEROL; GALACTOSAMINE; METHANOL; PLANT EXTRACT; POLOXAMER; STREPTOZOCIN; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

ALLIUM VICTORIALIS; ANGIOSPERM; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; DIABETES MELLITUS; DRUG EFFECT; DRUG EFFICACY; DRUG POTENCY; FLUID INTAKE; FOOD INTAKE; GARLIC; GLUCOSE BLOOD LEVEL; HYPERLIPIDEMIA; LIVER INJURY; MEDICINAL PLANT; NONHUMAN; PLANT BULB; PLANT LEAF; RAT; STREPTOZOCIN DIABETES; TRIACYLGLYCEROL BLOOD LEVEL;

EID: 0141927827     PISSN: 02533073     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (25)

1. Moon, K. S. (1984) Components and Use of Herbal Medicine, Scientific Encyclopedia., Pyongyang, 671-672.
2. Lawson, L. D., Wang, Z. J., and Hughes, B. G. (1991) γ -glutamyl-S-alkylcysteines in garlic and other Allium spp.: Precursors of age-dependent trans-1-propenyl thiosulfinates, Journal of Natural Products 54: 436-444.
3. Wijaya, C. H., Muchtani, D., Lalel, H. J., Zakaria, F., and Kowara, S. (1996) Antiplatelet aggregation potencies of some Allium spp. grown in Indonesia, Nat. Prod. Sci. 2: 37-42.
4. Liakopoulou-Kyriakides, M., Sinakos, Z., and Kyriakidids, D. A. (1985) Identification of alliin, a constituent of Allium cepa with an inhibitory effect on platelet aggregation, Phytochem. 24: 600-601.
5. Lee, K. T., Choi, J. H., Kim, D. H., Son, K. H., Kim, W. B., Kwon, S. H., and Park, H. J. (2001) Constituents and the antitumor principle of Allium victorialis var. platyphyllum, Archives of Pharmacal Research 24: 44-50.
6. Richmond, W. (1976) Use of cholesterol oxidase for assay of total and free cholesterol in serum by continuous flow analysis, Clin. Chem. 22: 1579.
7. McGowan, W., Artiss, J. D., and Strandbergh, D. R. (1983) A peroxidase coupled method for the colorimetric determination of serum triglycerides, Clin. Chem. 29: 538-542.
8. Reitman, S. and Frankel, S. (1957) A colorimetric method for the determination of serum glutamic oxaloacetic and glutamic pyruvic transaminase, Am. J. Clin. Pathol. 28: 56-60.
9. Weisner, I.S., Rawnsley, H.M., Brooks, F.P., and Senior, J.R. (1965) Sorbitol dehydrogenase in the diagnosis of liver disease. Am. J. Dig. Dis. 10: 147-151.
10. Wilson, G.L., Patton, N.J., McCord, J.M., Mullins, D.W., and Mossman, B.T. (1984) Mechanism of streptozotocin-induced damage in rat cells, Diabetologia 27: 587-591.
11. Hayek, A., Barela, T., Wogenrich, F., and Guardian, C.M. (1985) Fetal rat islet insulin deficiency following maternal administration of streptozotocin, Proc. Soc. Exp. Biol. Med. 180: 209-213.
12. Eizirik, D.L., De Lucio, M.A., Boschero, A.C., and Hoffmann, M.E. (1986) Phenanthroline, a metal chelator, protects against alloxan- but not streptozotocin-induced diabetes, J. Free Biol. Med. 2: 189-192.
13. Wout, Z.G.M., Pec, E.A., Maggiore, J. A., Williams, R. H., Palicharla, P., and Johnston, T. P. (1992) Poloxamer 407-mediated changes in plasma cholesterol and triglyceride following intraperitoneal injection to rats, J. Parenteral Sci. & Technol. 46(6): 192-200.
14. Johnston, T. P. and Palmer, W. K. (1993) Mechanism of poloxamer 407-induced hypertriglyceridemia in the rat, Biochem. Pharmacol. 46(6): 1037-1042.
15. Noll, T. and Groot, H. (1984) The critical steady-state hypoxic conditions in carbon tetrachloride-induced lipid peroxidation in rat liver microsomes, Biochem. Biophy. Acta 795: 356-362.
16. Recknagel, R.O. and Glende, E.A. (1989) Mechanisms of carbon tetrachloride toxicity, Phar. & Ther. 43: 139-154.
17. Decker, K. and Kepper, D. (1973) Galactosamine-induced liver injury. In "Progress in liver disease", Grune & Stratton, New York, 14, p. 183.
18. Reutter, W., Keppler, D., Lesch, R., and Decker, K. (1969) Glycoprotein metabolism in galactosamine-induced hepatitis. Verh. Dtsch. Ges. Inn. Med. 75: 363-365.
19. Keppler, D., Lesch, R., Reutter, W., and Decker, K. (1968) Experimental hepatitis induced by D-galactosamine, Exp. Mol. Pathol. 9: 279-290.
20. Mofty, S.K., Scrutton, M.C., Serroni, A., Nicolini, C., and Farber, J.L. (1975) Early, reversible plasma membrane injury in galactosamine-induced liver cell death, Am. J. Pathol. 79: 579-595.
21. Farber, J.L., Gill, G., and Konishi, Y. (1973) Prevention of galactosamine-induced liver cell necrosis by uridine, Am. J. Pathol. 72: 53-62.
22. Lesch, R., Reutter, W., Keppler, D., and Decker, K. (1970) Liver restitution after acute galactosamine hepatitis; autoradiographic and biochemical studies in rats, Exp. Mol. Pathol. 12: 58-69.