Accumulation of toxic elements in liver and bile in hyperlipidemy

Trace Elements and Electrolytes

Volumn 20, Issue 4, 2003, Pages 211-216

  Blazovics A ^a   Szentmihalyi K ^a   Rapavi, E ^a   Feher E ^a   Vinkler, P ^a  

^a SEMMELWEIS UNIVERSITY   (Hungary)

Author keywords

Hyperlipidemy; Toxic elements

Indexed keywords

ACUTE PHASE PROTEIN; CADMIUM; CHOLIC ACID; COPPER; DEOXYCHOLIC ACID; HEAVY METAL; IRON; MANGANESE; NICKEL; PROTEIN P53; SUNFLOWER OIL; TUMOR SUPPRESSOR PROTEIN; ZINC;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BILE; CARCINOGENESIS; CONTROLLED STUDY; CORRELATION ANALYSIS; DNA REPAIR; DRUG ACCUMULATION; ENZYME ACTIVITY; GENE EXPRESSION; HISTOPATHOLOGY; HYPERLIPIDEMIA; LIPID DIET; LIVER; LIVER METABOLISM; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN SYNTHESIS; RAT; RAT STRAIN; TISSUE DEGENERATION;

ANIMALIA; HELIANTHUS; RATTUS NORVEGICUS;

EID: 0141892165     PISSN: 09462104     EISSN: None     Source Type: Journal    
DOI: 10.5414/tep20211     Document Type: Article

References (32)

1. Biesel WR 1996 Nutrition and immune function: overwiev. J Nutr 126: S2611-S2615
2. Blázovics A, Fehér E, Fehér J 1992 Role of free radical reactions in experimental hyperlipidemia in the pathomechanism of fatty liver, In: Csomós G, Fehér J (eds) Free Radicals and Liver. Spinger, Berlin, pp 98-126
3. Blázovics A, Örsi F., Sípos P, Fehér J 1998 Free radical reactions in the bile: experimental and human studies. Curr Top Biophys 22 (Suppl B): 21-26
4. Blázovics A, Kovács Á, Lugasi A, Hagymási K, Bíró L, Fehér J 1999 Antioxidant defense in erythrocytes and plasma of patients with active and quiescent Crohn's disease and ulcerative colitis: a chemiluminescence study. Clin Chem 45: 895-896
5. Blázovics A, Abaza M, Sipos P, Szentmihályi K, Fehér E, Szilágyi M 2002 Biochemical and morphological changes in liver and gallbladder bile of broiler chicken exposed to heavy metals (cadmium, lead, mercury). Trace Elem Electrolytes 19: 42-47
6. Broska MM, Moniuszko-Jakoniuk, Jurczuk M, Galazyn-Sidorczuk M, Rogalska J 2000 Effect of short-term ethanol administration on cadmium retention and bioelement metabolism in rats continuously exposed to cadmium. Alcohol Alcohol 35: 439-445
7. Chen CY, Huang YL, Lin TH 1998 Association between oxidative stress and cytokine production in nickel-treated rats. Arch Biochem Biophys 356: 127-132
8. Chukhlovin AB, Tokalov SV, Yagunov AS, Westendorf J, Reincke H, Karbe L 2001 In vitro suppression of thymocyte apoptosis by metal-rich complex environmental mixtures: potential role of zinc and cadmium excess. Sci Total Environ 281: 153-163
9. Clopton DA, Saltman P 1997 Copper specific damage in human erythrocytes exposed to oxidative stress. Biol Trace Elem Res 56: 231-240
10. Czauderna M, Rochalska M 1989 Interaction between Se and Cr and distribution of Zn, Rb, Co, and Fe in mice given chromate ions and selenium compounds. J Radioanal Nucl Chem 134: 383-392
11. Debacker V, Schiettecatte LS, Jauniaux T, Bouquegneau JM 2001 Influence of age, sex and body condition on zinc, copper, cadmium and metallothioneins in common guillemots (Uria aalge) stranded at Belgian coast. Mar Environ Res 52: 427-444
12. Dominicus DAR. Gunshin H, Ariizumi M 1992 Effect of toluene inhalation on the liver and kidney trace element concentration levels in male Wistar rats. Nutr Res 12: 419-426
13. Eder K, Kirchgessner K 1994 Zinc deficiency and concentrations of lipids in plasma of rats. Trace Elem Electrolytes 13: 60-65
14. Fehér J, Blázovics A, Lengyel G 1997 Toxic liver diseases with intrahepatic cholestasis. Prog Hepatogastroenterol 2: 19-25
15. Feltelius N Hallgren R, Lindh G 1988 Redistribution of cellular mineral and trace element stores in HLA-B27-positive relatives of patients with ankilosing spondylitis - a marker of hidden inflammatory disease. J Rheumatol 15: 308-314
16. Gelagutashvili ES, Mikeladze IV, Sapojnikova NA 1997 Binding and the nature of Co(II), Ni(II), Zn(II) ion interaction with nucleosomes. J Inorg Biochem 65: 159-161
17. Goebeler M, Meinardus-Hager G, Roth J, Goerdt S, Sorg C 1993 Nickel chloride and cobalt chloride, two common contact senzitizers, directly induce expresion of intracellular adhesion molecule-1 (ICAM-1) vascular cell adhesion molecule-1 (VCAM-1) and endothelial leucocyte adhesion molecule (ELAM-1) by endothelial cells. J Invest Dermatol 100: 759-765
18. Hartwig A 1998 Carcinogenicity of metal compounds: possible role of DNA repair inhibition. Toxicol Lett 102/103: 235-239
19. Hartwig A, Mullenders LHF, Schlepegrell R, Kasten U, Beyersmann D 1994 Nickel(II) interferes with the incision step in nucleotide excision repair in mammalian cells. Cancer Res 54: 4045-4051
20. Isfaoun A, Bureau F, Mouly-Boudey M, Drosdowsky M, Arhan P, Bougle D 1997 Relationships between iron and zinc metabolism: predictive value of digestive absorption on tissue storage. J Trace Elem Med Biol 11: 23-27
21. Kimura M, Yokoi K 1996 Iron accumulation in tissues of magnesium-deficient rats with dietary iron overload: experimental hemochromatosis model. Biol Trace Elem Res 41: 177-198
22. Lacka B, Grzeszczal W, Strojek K, Twardowska SK 1997 Lipid peroxidation, antioxidant enzyme activity, and trace element concentration in primarily hypertension. Trace Elem Electrolytes 14: 61-65
23. Maehle L, Metcalf RA, Ryberg D, Bennett WP, Harris CC, Haugen A 1992 Altered p53 gene structure and expression in human epithelia cells after exposure to nickel. Cancer Res 52: 218-221
24. Mercer JFB, Stevenson T, Wake SA, Mitropoulos G, Camakaris J, Danks DM 1991 Developmental variation in copper, zinc and metallothionein mRNA in brindled mutant and nutritionally copper deficient mice. Biochim Biophys Acta Mol Basis Dis 1097: 205-211
25. Schroeder JJ, Cousins RJ 1990 Interleukin 6 regulates metallothionein gene expression and zinc metabolism in hepatocyte monolayer cultures. Proc Natl Acad Sci USA 87: 3137-3141
26. Sigel A, Sigel M 1999 Metal Ions in Biological Systems. Marcel Dekker, Basel
27. Stohs SJ, Bagchi D 1995 Oxidative mechanisms in the toxicity of metal ions. Free Rad Biol Med 18: 321-336
28. Szentmihályi K, Blázovics A, Kocsis I, Fehér E, Lakatos B, Vinkler P 2000 The effect of fat-rich diet and alcohol on ion concentration in bile fluid in rats. Acta Aliment Hung 29: 359-366
29. Theocharis S, Margeli A, Panayiotidis P 1991 Effects of various metals on DNA synthesis and lymphokines production by human peripheral blood lymphocytes in vitro. Comp Biochem Physiol C Pharmacol Toxicol Endocrinol 99: 131-133
30. Wagner M, Klein CL, Kleinert H, Euchenhofer C, Forstermann U, Kirkpatrick CJ 1997 Heavy metal ion induction of adhesion molecules and cytokines in human endothelial cells. Pathobiol 65: 241- 252
31. Wildman REC, Mao S 2001 Tissue-specific alterations in lipoprotein lipase activity in copper-deficient rats. Biol Trace Elem Res 80: 221-229
32. Yuregir GT, Kayrin L, Curuk MA, Acarturk E, Unlukurt I 1994/1995 Correlation between trace elements and lipid profiles. J Trace Elem Exp Med 7: 113-118