Sterilization of parenterals with microwaves as an alternative to autoclavation;Sterilisation von parenteralia mit mikrowellen als alternative zur autoklavierung

Pharmazeutische Industrie

Volumn 65, Issue 9 A, 2003, Pages 977-983

  Heun, Georg ^a   Tinkov, Steliyan ^b  

^a ANHALT UNIVERSITY OF APPLIED SCIENCES   (Germany)

^b MEDICAL UNIVERSITY OF SOFIA   (Bulgaria)

Author keywords

[No Author keywords available]

Indexed keywords

PARENTERAL SOLUTION;

AUTOCLAVE; DRUG STERILITY; MICROWAVE IRRADIATION; PHARMACEUTICAL ENGINEERING; REVIEW; THERMOSTABILITY;

EID: 0141869671     PISSN: 0031711X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (20)

1. European Pharmacopoeia, 4th Ed., Council of Europe (EDQM) (2001)
2. The United States Pharmacopeia, 26th Ed., United States Pharmacopeial Convention (2003)
3. The Japanese Pharmacopoeia, 14th Ed., Society of Japanese Pharmacopoeia (2001)
4. Spencer, P. L., U.S. patent 2,495,429
5. Kinetics of microbial inactivation for alternative food processing technologies - microwave and radio frequency Processing, U.S. Food and Drug Administration Center for Food Safety and Applied Nutrition, June 2 (2000)
6. Sasaki, K., Honda, W., Shimizu, K. et. al., Microwave continuous sterilization of injection ampoules, PDA J. Pharm. Sci. Tech. 50, 172 (1996)
7. Telekommunikationsgesetz (TKG) vom 25. 7. 1996, BGBl. I, S. 1120, zuletzt geändert durch Art. 1 und 2 des Ersten Gesetzes zur Änderung des Telekommunikationsgesetzes vom 21. 10. 2002, BGBl. I, S. 4186
8. Frequenzbereichszuweisungsplanverordnung (FreqBZPV) vom 26. 4. 2001, BGBl. I, S. 778
9. Mudgett, R. E., in: R. V. Decareau, Microwaves in the food processing industry, Academic Press, Orlando - Tokio, 15 (1985)
10. Rauxel Dornik, M., Pharmazeutisch-technologische Untersuchungen über Wechselwirkungen von Arzneizubereitungen mit Mikrowellen, Dissertation, Universität Münster (1991)
11. Olsen, C. M., Drake, C. L., Bunch, S. L., Some biological effects of micromave energy, J. Microwave Power 1, 45 (1966)
12. Khalil, H., Villota, R., The effect of microwave sublethal heating on the ribonucleic acids of staphylococcus aureus, J. Food Protect. 52, 544 (1989)
13. Kozempel, M., Cook, R. D., Scullen, O. J. et al., Development of a processor for detecting non-thermal effects of a microwave energy on microorganisms at low temperature, J. Food Proc. and Preservation 24, 287 (2000)
14. Koutchma, T., Le Bail, A., Ramaswamy, H. S., Comparative experimental evaluation of microbial destruction in continuous-flow microwave and conventional heating systems, Canadian Biosystems Engineering / Le génie des biosystèmes au Canada 43, 3.1 (2001)
15. Wallhäuser, K. H., Praxis der Sterilisation, 4. Aufl., S. 250, Georg Thieme Verlag, Stuttgart - New York (1988)
16. Gröning, R., Keimzahlreduzierung durch Mikrowellen, Pharm. Ztg. 41, 2621 (1985)
17. Janske, U., Entkeimung und Entwesung pharmazeutischer Zubereitungen und Grundstoffe durch Mikrowellen, Dissertation, Technische Hochschule Braunschweig (1987)
18. Göning, R., Janske, U., Offenlegungsschrift DE3612606A1
19. Sasaki, K., Honda, W., Miyake, Y., Evaluation of high-temperature and short-time sterilization of injection ampules by microwave heating, PDA J. Pharm. Sci. Tech. 52, 5 (1998)
20. Sasaki, K., Honda, W., Ohsawa, S. et al., Validation of a microwave sterilizer for injection ampules, PDA J. Pharm. Sci. Tech. 53, 60 (1999)