Total cholesterol and mortality in the elderly

Journal of Internal Medicine

Volumn 254, Issue 4, 2003, Pages 353-362

  Casiglia, Edoardo ^a   Mazza, A ^a   Tikhonoff, V ^a   Scarpa, R ^a   Schiavon, L ^a   Pessina, A C ^a  

^a UNIVERSITY OF PADOVA   (Italy)

Author keywords

Cancer; Cardiovascular; Epidemiology; Human; Population; Risk

Indexed keywords

CHOLESTEROL;

ACCIDENT; AGED; ARTICLE; BODY MASS; CANCER; CHOLESTEROL BLOOD LEVEL; CIGARETTE SMOKING; CLINICAL TRIAL; CORONARY RISK; DEMENTIA; ENTEROPATHY; FEMALE; HEART FAILURE; HEMORRHAGIC SHOCK; HOMICIDE; HUMAN; INFECTION; ISCHEMIC HEART DISEASE; ITALY; KIDNEY DISEASE; LIVER CIRRHOSIS; LUNG EMBOLISM; MAJOR CLINICAL STUDY; MALE; MALNUTRITION; MATHEMATICAL COMPUTING; MORTALITY; MULTIVARIATE ANALYSIS; PARKINSON DISEASE; PRIORITY JOURNAL; RESPIRATORY TRACT DISEASE; RISK FACTOR; SEX DIFFERENCE; STROKE; SUICIDE; SURVIVAL RATE;

AGED; AGED, 80 AND OVER; BODY MASS INDEX; CARDIOVASCULAR DISEASES; CHOLESTEROL; FEMALE; HUMANS; MALE; MORTALITY; NEOPLASMS; NUTRITION DISORDERS; PROSPECTIVE STUDIES; RISK FACTORS; SEX FACTORS; SMOKING;

EID: 0141862283     PISSN: 09546820     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2796.2003.01200.x     Document Type: Article

References (56)

1. LaRosa JC. Is there a relationship between cholesterol reduction, low levels of cholesterol and mortality? Rev Esp Cardiol 1995; 48 (Suppl. 2): 14-17.
2. Manolio TA, Ettinger WH, Tracy RP et al. Epidemiology of low cholesterol levels in older adults. The Cardiovascular Health Study. Circulation 1993; 87: 728-37.
3. Forette B, Tortrat D, Wolmark Y. Cholesterol as risk factor for mortality in elderly women. Lancet 1989; 1: 868-70.
4. Oster P, Muchowsky H, Heuck CC, Schlierf G. The prognostic significance of hypocholesterolemia in hospitalized patients. Klin Wochenschr 1981; 59: 857-60.
5. Beaglehole R, Foulkes MA, Prior IA, Eyles EF. Cholesterol and mortality in New-Zealand Maoris. Br Med J 1980; 280: 285-87.
6. Fagot-Campagna A, Hanson RL, Narayan KM et al. Serum cholesterol and mortality rate in a Native American population with low cholesterol concentrations: a U-shaped association. Circulation 1997; 96: 1408-15.
7. Pekkanen J, Nissinen A, Vartiainen E, Salonen JT, Punsar S, Karvonen MJ. Changes in serum cholesterol level and mortality: a 30-year follow-up. The Finnish cohorts of the Seven Countries Study. Am J Epidemiol 1994; 139: 155-65.
8. Harmsen P, Rosengren A, Tsipogianni A, Wilhelmsen L. Risk factors for stroke in middle-aged men in Goteborg, Sweden. Stroke 1990; 21: 223-29.
9. Haheim LL, Holme I, Hjermann I, Leren P. Risk factors of stroke incidence and mortality. A 12-year follow-up of the Oslo Study. Stroke 1993; 24: 1484-89.
10. Song YM, Sung J. Body mass index and mortality: a twelve-year prospective study in Korea. Epidemiology 2001; 12: 173-79.
11. Stengard JH, Kardia SL, Tervahauta M, Ehnholm C, Nissinen A, Sing CF. Utility of the predictors of coronary heart disease mortality in a longitudinal study of elderly Finnish men aged 65 to 84 years is dependent on context defined by Apo-E genotype and area of residence. Clin Genet 1999; 56: 367-77.
12. Houterman S, Boshuizen HC, Verschuren WM et al. Predicting cardiovascular risk in the elderly in different European countries. Eur Heart J 2002; 23: 294-300.
13. Weijenberg MP, Feskens EJ, Kromhout D. Total and high density lipoprotein cholesterol as risk factors for coronary heart disease in elderly men during five years of follw-up. The Zutphen Elderly Study. Am J Epidemiol 1996; 143: 151-58.
14. Menotti A, Kromhout D, Nissinen A et al. Short-term all-cause mortality and its determinants in elderly male populations in Finland, The Netherlands and Italy: The FINE Study. Finland, Italy, Netherlands Elderly Study. Prev Med 1996; 25: 319-26.
15. Tervahauta M, Pekkanen J, Nissinen A. Risk factors of coronary artery disease among elderly men with and whitout preexisting coronary heart desease. Finnish cohorts of the Seven Countries Study. JACC 1995; 26: 1623-29.
16. Shipley MJ, Pocock SJ, Marmot MG. Does plasma cholesterol concentration predict mortality from coronary heart disease in elderly people? 18 year follow up in Whitehall study. BMJ 1991; 303: 89-92.
17. Reed D, Yano K, Kagan A. Lipids and lipoproteins as predictors of coronary heart disease, stroke, and cancer in the Honolulu Heart Program. Am J Med 1986; 80: 871-78.
18. Keys A, Aravanis C, Blackburn H et al. Serum cholesterol and cancer mortality in the Seven Countries Study. Am J Epidemiol 1985; 121: 870-83.
19. Kagan A, McGee DL, Yano K, Rhoads GG, Nomura A. Serum cholesterol and mortality in a Japanese-american population: the Honolulu Heart program. Am J Epidemiol 1981; 114: 11-20.
20. Song YM, Sung J, Kim JS. Which cholesterol level is related to the lowest mortality in a population with low mean cholesterol level: a 6.4-year follow-up study of 482.472 Korean men. Am J Epidemiol 2000; 151: 739-47.
21. Anonymous. Circulating cholesterol level and risk of death from cancer in men aged 40 to 69 years. Experience of an international collaborative group. JAMA 1982; 248: 2853-859.
22. Houterman S, Verschuren WM, Giampaoli S et al. Total but not high-density lipoprotein cholesterol is consistently associated with coronary heart disease mortality in elderly men in Finland, Italy, and The Netherlands. Epidemiology 2000; 11: 327-32.
23. Iribarren C, Reed DM, Chen R, Yano K, Dwyer JH. Low serum cholesterol and mortality. Which is the cause and which is the effect? Circulation 1995; 92: 2396-403.
24. Benfante R, Reed D. Is elevated serum cholesterol level a risk factor for coronary heart disease in the elderly? JAMA 1990; 263: 393-96.
25. Lindquist P, Bengtsson C, Lissner L, Björkelund C. Cholesterol and triglyceride concentration as risk factors for miocardial infraction and death in women, with special reference to influence of age. J Intern Med 2002: 251: 484-89.
26. Palatini P, Casiglia E, Julius S, Pessina AC. High heart rate. A risk factor for cardiovascular death in elderly men. Arch Int Med 1999; 159: 585-92.
27. Casiglia E, Spolaore P, Mormino P et al. The CASTEL project (CArdiovascular STudy in the ELderly): protocol, study design, and preliminary results of the initial survey. Cardiologia 1991; 36: 569-76.
28. Casiglia E, Spolaore P, Ginocchio G et al. Proteinuria predicts mortality among elderly but not among 'very old' subjects. J Nephrol 1993; 5: 89-93.
29. Casiglia E, Palatini P. Cardiovascular risk factors in the elderly. J Hum Hypert 1998; 12: 575-81.
30. Ledru F, Ducimetiere P, Battaglia S et al. New diagnostic criteria for diabetes and coronary artery disease: insights from an angiographic study. JACC 2001; 37: 1543-50.
31. Olivarius ND, Mogensen CE. Danish general practitioners' estimation of urinary albumin concentration in the detection of proteinuria and microalbuminuria. Br J Gen Pract 1995; 45: 71-73.
32. Simons LA, McCallum J, Friedlander Y, Simons J. Predictors of mortality in the prospective Dubbo Study of Australian Elderly. Aust N Z J Med 1996; 26: 40-48.
33. Schatzkin A, Hoover RN, Taylor PR et al. Serum cholesterol and cancer in the NHANES I epidemilogic follow-up study. National Health and Nutrition Examination Survey. Lancet 1987; 2: 298-301.
34. Stemmermann GN, Chyou PH, Kagan A, Nomura AM, Yano K. Serum cholesterol and mortality among Japanese-American men. The Honolulu (Hawaii) Heart program. Arch Intern Med 1991; 15: 969-72.
35. Wingard DL, Criqui MH, Holdbook MJ, Barrett-Connor E. Plasma cholesterol and cancer morbidity and mortality in adult community. J Chronic Dis 1984; 37: 401-06.
36. Delahaye F, Brukert E, Thomas D, Emmerich J, Richard JL. Serum cholesterol and cancer. Is there a causal relationship? Arch Mal Coeur Vaiss 1992; 85 (Spec. no. 3): 37-45.
37. Schuit AJ, Van Dijk CE, Dekker JM, Schouten EG, Kok FJ. Inverse association between serum total cholesterol and cancer mortality in Dutch civil servants. Am J Epidemiol 1993; 137: 966-76.
38. Salmond CE, Beaglehole R, Prior IA. Are low cholesterol values associated with excess mortality? Br Med J 1985; 290: 422-24.
39. Sidney S, Farquhar JW. Cholesterol, cancer, and public health policy. Am J Med 1983; 75: 494-508.
40. Chang AK, Barrett-Connor E, Edelstein S. Low plasma cholesterol predicts an increased risk of lung cancer in elderly women. Prev Med 1995; 24: 557-62.
41. Iso H, Naito Y, Kitamura A et al. Serum total cholesterol and mortality in a Japanese population. J Clin Epidemiol 1994; 47: 961-69.
42. Harris T, Cook EE, Garrison R, Higgins M, Kannel W, Goldman L. Body mass index and mortality among non-smoking older persons. The Framingham Heart Study. JAMA 1988; 259: 1520-24.
43. Nakayama K, Koyohara Y, Kato I, Iwamoto H, Ueda K, Eujishima M. Effect of body mass index on morbidity and mortality in a general Japanese population. The Hisayama Study. Nippon Ronen Igakkai Zasshi 1997; 34: 935-41.
44. Delgado-Rodriguez M, Medina-Cuadros M, Gomez-Ortega A et al. Cholesterol and serum albumin levels as predictors of cross infection, death, and length of hospital stay. Arch Surg 2002; 137: 805-12.
45. Ellison LF, Morrison HI. Low serum cholesterol concentration and risk of suicide. Epidemiology 2001; 12: 168-72.
46. Lindberg G, Rastam L, Gullberg B, Eklund GA. Low serum cholesterol concentration and short term mortality from injuries in men and women. BMJ 1992; 305: 277-79.
47. Iribarren C, Jacobs DR, Sadler M, Claxton AJ, Sidney S. Low total serum cholesterol and intracerebral hemorrhagic stroke: is the association confined to elderly men? The Kaiser Permanente Medical Care Program. Stroke 1996; 27: 1993-98.
48. Iribarren C, Reed DM, Burchfiel CM, Dwyer JH. Serum total cholesterol and mortality. Confounding factors and risk modification in Japanese-American men. JAMA 1995; 273: 1926-32.
49. Kronmal RA, Cain KC, Ye Z, Omenn GS. Total serum cholesterol levels and mortality risk as a function of age. A report based on the Framingham data. Arch Intern Med 1993; 153: 1065-73.
50. Gordon DJ, Rilkind BM. Treating high blood cholesterol in the older patient. Am J Cardiol 1989; 63: 48-52H.
51. Krumholz HM, Seeman TE, Merrill SS et al. Lack of association between cholesterol and coronary heart disease mortality and morbidity and all-cause mortality in persons older than 70 years. JAMA 1994; 272: 1335-40.
52. Bo M, Fiandra U, Fonte G, Bobbio M, Fabris F. Cholesterol and long-term mortality after acute myocardial infarction in elderly patients. Age Ageing 1999; 28: 313-15.
53. Barrett-Connor E. Hypercholesterolemia predicts early death from coronary heart disease in elderly men but not women. The Rancho-Bernardo Study. Ann Epidemiol 1992; 2: 77-83.
54. Higgins M, Keller JB. Cholesterol, coronary heart disease and total mortality in middle-aged and elderly men and women in Tecumseh. Ann Epidemiol 1992; 2: 69-76.
55. Rywik SL, Manolio TA, Pajak A et al. Association of lipids and lipoprotein level with total mortality and mortality caused by cardiovascular and cancer diseases (Poland and United States collaborative study on cardiovascular epidemiology). Am J Cardiol 1999; 84: 540-48.
56. Casiglia E, Mazza A, Tikhonoff V et al. Weak effect of hypertension and other classic risk factors in the elderly who have already paid their toll. J Human Hypert 2002; 16: 21-31.