The detrusor muscle cell in bladder outlet obstruction: Ultrastructural and morphometric findings

Scandinavian Journal of Urology and Nephrology

Volumn 37, Issue 4, 2003, Pages 309-315

  Holm, Nina Raae ^a   Horn, Thomas ^a   Smedts, Frank ^b   Nordling, Jørgen ^a   De La Rossette, Jean ^c  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b Foundation of Collaborating Hospital   (Netherlands)

^c RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Bladder outlet obstruction; Detrusor; Smooth muscle; Ultrastructure

Indexed keywords

ELASTIN;

ADULT; AGED; ARTICLE; BLADDER BIOPSY; BLADDER NECK STENOSIS; CELL JUNCTION; CELL ULTRASTRUCTURE; CONTROLLED STUDY; CORRELATION ANALYSIS; DETRUSOR MUSCLE; DIAGNOSTIC PROCEDURE; ELECTRON MICROSCOPY; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; MUSCLE BIOPSY; MUSCLE HYPERTROPHY; PRIORITY JOURNAL; PROTEIN LOCALIZATION; SMOOTH MUSCLE FIBER; URODYNAMICS;

ADULT; AGED; AGED, 80 AND OVER; HUMANS; MALE; MIDDLE AGED; MYOCYTES, SMOOTH MUSCLE; URINARY BLADDER; URINARY BLADDER NECK OBSTRUCTION; URODYNAMICS;

EID: 0141839670     PISSN: 00365599     EISSN: None     Source Type: Journal    
DOI: 10.1080/00365590310014751     Document Type: Article

References (22)

1. Abrams PH, Griffiths DJ. The assessment of prostatic obstruction from urodynamic measurements and from residual urine. Br J Urol 1979; 51: 129-34.
2. Chatelain C, Denis L, Foo KT, Khoury S, McConnell J, eds. Benign prostatic hyperplasia. Plymouth, UK: Health Publication Ltd., 2001.
3. Kortmann BBM, Holm NR, Smedts F, Horn T, Nordling J, Kiemeney LALM, et al. Bladder outlet obstruction does not change bladder wall morphology. J Urol 2003: In press.
4. Holm NR, Horn T, Hald T. Detrusor in ageing and obstruction. Scand J Urol Nephrol 1995; 29: 45-9.
5. Elbadawi A. Functional pathology of urinary bladder muscularis: the new frontier in diagnostic uropathology. Semin Diagn Pathol 1993; 10: 314-54.
6. Elbadawi A, Yalla SV, Resnick NM. Structural basis of geriatric voiding dysfunction. I. Methods of a prospective ultrastructural/urodynamic study and an overview of the findings. J Urol 1993; 150: 1650-6.
7. Tse V, Wills E, Szonyi G, Khadra MH. The application of ultrastructural studies in the diagnosis of bladder dysfunction in a clinical setting. J Urol 2000; 163: 535-9.
8. Kortmann BB, Sonke GS, Wijkstra H, Nordling J, Kallestrup E, Holm NR, et al. Intra- and inter-investigator variation in the analysis of pressure-flow studies in men with lower urinary tract symptoms. Neurourol Urodyn 2000; 19: 221-32.
9. Holm NR, Horn T, Elbadawi A, Skjoldbye B, Nordling J. A new technique for detrusor biopsy and its applicability in the ultrastructural study and diagnosis of voiding dysfunction. Br J Urol 1996; 77: 785-91.
10. Hansen BJ, Flyger H, Brasso K, Schou J, Nordling J, Thorup AJ, et al. Validation of the self-administered Danish Prostatic Symptom Score (DAN-PSS-1) system for use in benign prostatic hyperplasia. Br J Urol 1995; 76: 451-8.
11. Chatelain C, Denis L, Foo KT, Khoury S, McConnell J, Abrams PH, et al. Evaluation and treatment of lower urinary tract symptoms (LUTS) in older men. In: Chatelain C, Denis L, Foo KT, Khoury S, McConnell J, eds. Benign prostatic hyperplasia. Plymouth, UK: Health Publication Ltd., 2001: 519-34.
12. Lim CS, Abrams PH. The Abrams-Griffiths nomogram. World J Urol 1995; 13: 34-9.
13. Elbadawi A, Light JK. Distinctive ultrastructural pathology of non-ulcerative interstitial cystitis: new observations and their potential significance in pathogenesis. Urol Int 1996; 56: 137-62.
14. Horn T, Holm NR, Hald T. Interstitial cystitis. Ultrastructural observations on detrusor smooth muscle cells. APMIS 1998; 106: 909-16.
15. Hansen F, Olsen L, Atan A, Jakobsen H, Nordling J. Pressure-flow studies: an evaluation of within-testing reproducibility - validity of the measured parameters. Neurourol Urodyn 1997; 16: 521-32.
16. Tammela TL, Schafer W, Barrett DM, Abrams PH, Hedlund H, Rollema HJ, et al. Repeated pressure-flow studies in the evaluation of bladder outlet obstruction due to benign prostatic enlargement. Finasteride Urodynamics Study Group. Neurourol Urodyn 1997; 18: 17-24.
17. Holm NR, Horn T, Nordling J. Fixation of human detrusor smooth muscle cells: role of osmolarity and magnesium ions on the ultrastructural morphology. Urol Res 1997; 25: 283-9.
18. Elbadawi A, Yalla SV, Resnick NM. Structural basis of geriatric voiding dysfunction. III. Detrusor overactivity. J Urol 1993; 150: 1668-80.
19. Carey MP, De Jong S, Friedhuber A, Moran PA, Dwyer PL, Scurry J. A prospective evaluation in women, using electron microscopy and immunohistochemistry. Br J Urol 2000; 86: 970-6.
20. Elbadawi A, Yalla SV, Resnick NM. Structural basis of geriatric voiding dysfunction. II. Ageing detrusor: normal versus impaired contractility. J Urol 1993; 150: 1657-67.
21. Hailemariam S, Elbadawi A, Yalla SV, Resnick NM. Structural basis of geriatric voiding dysfunction. V. Standardised protocols for routine ultrastructural study and diagnosis of endoscopic detrusor biopsies. J Urol 1997; 157: 1783-801.
22. Elbadawi A, Hailemariam S, Yalla SV, Resnick NM. Structural basis of geriatric voiding dysfunction. VI. Validation and update of diagnostic criteria in 71 detrusor biopsies. J Urol 1997; 157: 1802-13.