Immunology of paraneoplastic syndromes: Overview

Annals of the New York Academy of Sciences

Volumn 998, Issue , 2003, Pages 178-186

  Posner, Jerome B ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

Autoantibodies; Autoimmunity; Cancer; Paraneoplastic

Indexed keywords

IMMUNOGLOBULIN;

ALLOTYPE SUPPRESSION; ANTIBODY TITER; ANTIGEN ANTIBODY REACTION; AUTOIMMUNITY; AUTOPSY; BRAIN METASTASIS; CANCER CYTODIAGNOSIS; CANCER IMMUNOTHERAPY; CANCER INCIDENCE; CEREBROSPINAL FLUID; CLINICAL FEATURE; CONFERENCE PAPER; DISEASE ASSOCIATION; DISEASE SEVERITY; EATON LAMBERT SYNDROME; HUMAN; IMMUNOPATHOGENESIS; INFLAMMATORY INFILTRATE; MYASTHENIA GRAVIS; NERVE CELL NECROSIS; NEUROMUSCULAR SYNAPSE; ONSET AGE; PARANEOPLASTIC SYNDROME; PLASMAPHERESIS; T LYMPHOCYTE; THYMUS CANCER;

EID: 0141839045     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1196/annals.1254.018     Document Type: Conference Paper

References (34)

1. POSNER, J.B. 1995. Neurologic Complications of Cancer, Davis. Philadelphia.
2. LEYN, J. & H. DEGREEF. 2001. Paraneoplastic pemphigus in a patient with a thymoma. Dermatology 202: 151-154.
3. POSNER, J.B. & J.O. DALMAU. 2000. Paraneoplastic syndromes of the nervous system. Clin. Chem. Lab. Med. 38: 117-122.
4. PETERSON, K., M.K. ROSENBLUM, H. KOTANIDES & J.B. POSNER. 1992. Paraneoplastic cerebellar degeneration. I. A clinical analysis of 55 anti-Yo antibody positive patients. Neurology 42: 1931-1937.
5. MASON, W.P., F. GRAUS, B. LANG et al. 1997. Small-cell lung cancer, paraneoplastic cerebellar degeneration, and the Lambert-Eaton myasthenic syndrome. Brain 120: 1279-1300.
6. LEVY, Y., A. AFEK, Y. SHERER et al. 1998. Malignant thymoma associated with autoimmune diseases: a retrospective study and review of the literature. Semin. Arthritis Rheum. 28: 73-79.
7. REES, J.H., S.F. HAIN, M.R. JOHNSON et al. 2001. The role of [(18)F]fluoro-2-deoxyglucose-PET scanning in the diagnosis of paraneoplastic neurological disorders. Brain 124: 2223-2231.
8. VERSCHUUREN, J., L. CHUANG, M.K. ROSENBLUM et al. 1996. Inflammatory infiltrates and complete absence of Purkinje cells in anti-Yo associated paraneoplastic cerebellar degeneration. Acta Neuropathol. 91: 519-525.
9. OPPENHEIM, H. 1888. Uber Hirnsymptome bei Carcinomatose ohne nachweisbare. Veranderungen im Gehirn. Charite-Ann. (Berlin) 13: 335-344.
10. DENNY-BROWN, D. 1948. Primary sensory neuropathy with muscular changes associated with carcinoma. J. Neurol. Neurosurg. Psychiatry 11: 73-87.
11. HENSON, R.A., H.L. HOFFMAN & H. URICH. 1965. Encephalomyelitis with carcinoma. Brain 88: 449-464.
12. VOLTZ, R., S.H. GULTEKIN, M.R. ROSENFELD et al. 1999. A serologic marker of paraneoplastic limbic and brain-stem encephalitis in patients with testicular cancer. N. Engl. J. Med. 340: 1788-1795.
13. GULTEKIN, S.H., M.R. ROSENFELD, R. VOLTZ et al. 2000. Paraneoplastic limbic encephalitis: neurological symptoms, immunological findings, and tumour association in 50 patients. Brain 123: 1481-1494.
14. ANTUNES, N.L., Y. KHAKOO, K.K. MATTHAY et al. 2000. Antineuronal antibodies in patients with neuroblastoma and paraneoplastic opsoclonus-myoclonus. J. Pediatr. Hematol. Oncol. 22: 315-320.
15. YU, Z.Y., T.J. KRYZER, G.E. GRIESMANN et al. 2001. CRMP-5 neuronal autoantibody: marker of lung cancer and thymoma-related autoimmunity. Ann. Neurol. 49: 146-154.
16. FURNEAUX, H.M., L. REICH & J.B. POSNER. 1990. Autoantibody synthesis in the central nervous system of patients with paraneoplastic syndromes. Neurology 40: 1085-1091.
17. DARNELL, R.B. & M.L. ALBERT. 2000. Cdr2-specific CTLs are detected in the blood of all patients with paraneoplastic cerebellar degeneration analyzed. Ann. Neurol. 48: 270.
18. VOLTZ, R., J. DALMAU, J.B. POSNER & M.R. ROSENFELD. 1998. T-cell receptor analysis in anti-Hu associated paraneoplastic encephalomyelitis. Neurology 51: 1146-1150.
19. DALMAU, J., H.M. FURNEAUX, M.K. ROSENBLUM et al. 1991. Detection of the anti-Hu antibody in specific regions of the nervous system and tumor from patients with paraneoplastic encephalomyelitis/sensory neuronopathy. Neurology 41: 1757-1764.
20. GRAUS, F., J. DALMAU, R. REÑÉ et al. 1997. Anti-Hu antibodies in patients with small-cell lung cancer: association with complete response to therapy and improved survival. J. Clin. Oncol. 15: 2866-2872.
21. CARPENTIER, A.F., M.R. ROSENFELD, J-Y. DELATTRE et al. 1998. DNA vaccination with HuD inhibits growth of a neuroblastoma in mice. Clin. Cancer Res. 4: 2819-2824.
22. ROJAS, I., F. GRAUS, F. KEIME-GUIBERT et al. 2000. Long-term clinical outcome of paraneoplastic cerebellar degeneration and anti-Yo antibodies. Neurology 55: 713-715.
23. JOHNSTON, I., D.L. GILDAY & E.B. HENDRICK. 1975. Experimental effects of steroids and steroid withdrawal on cerebrospinal fluid absorption. J. Neurosurg. 42: 690-695.
24. RICKMAN, O.B., J.E. PARISI, Z.Y. YU et al. 2000. Fulminant autoimmune cortical encephalitis associated with thymoma treated with plasma exchange. Mayo Clin. Proc. 75: 1321-1326.
25. HAGIWARA, H., S. ENOMOTO-NAKATANI, K. SAKAI et al. 2001. Stiff-person syndrome associated with invasive thymoma: a case report. J. Neurol. Sci. 193: 59-62.
26. HERRMANN, D.N., M. BLAIVAS, J.J. WALD & E.E. FELDMAN. 2000. Granulomatous myositis, primary biliary cirrhosis, pancytopenia, and thymoma. Muscle Nerve 23: 1133-1136.
27. GHEZZI, P.M., P.F. BASSO & R. MONTANINI. 1994. Association of neuromyotonia with peripheral neuropathy, myasthenia gravis, and thymoma: a case report. Ital. J. Neurol. Sci. 15: 307-310.
28. MYGLAND, Å., A. VINCENT, J. NEWSOM-DAVIS et al. 2000. Autoantibodies in thymoma-associated myasthenia gravis with myositis or neuromyotonia. Arch. Neurol. 57: 527-531.
29. ANSEVIN, C.F. & P. AGAMANOLIS. 1996. Rippling muscles and myasthenia gravis with rippling muscles. Arch. Neurol. 53: 197-199.
30. HO, W.K.W. & J.D. WILSON. 1993. Hypothermia, hyperhidrosis, myokymia, and increased urinary excretion of catecholamines associated with a thymoma. Med. J. Aust. 158: 787-788.
31. KASTRUP, O., S. MEYRING & H.C. DIENER. 2001. Atypical paraneoplastic brainstem encephalitis associated with anti-Ri-antibodies due to thymic carcinoma with possible clinical response to immunoglobulins. Eur. Neurol. 45: 285-287.
32. KULLING, D., C.E. REED, G.N. VERNE et al. 1997. Intestinal pseudo-obstruction as a paraneoplastic manifestation of malignant thymoma. Am. J. Gastroenterol. 92: 1564-1566.
33. LEE, E.K., R.A. MASELLI, W.G. ELLIS & M.A. AGIUS. 1998. Morvan's fibrillary chorea: a paraneoplastic manifestation of thymoma. J. Neurol. Neurosurg. Psychiatry 65: 857-862.
34. OHTAKE, T., M. NISHIMURA & M. ODA. 1999. Multifocal polyradiculoneuropathy and carcinoma of the thymus. J. Neurol. Sci. 168: 62-67.