Assessment of patient performance of the HandiHaler® compared with the metered dose inhaler four weeks after instruction

Respiratory Medicine

Volumn 97, Issue 10, 2003, Pages 1126-1133

  Dahl, R ^a   Backer, V ^b   Ollgaard, B ^c   Gerken, F ^c   Kesten, S ^c  

^a AARHUS UNIVERSITY HOSPITAL   (Denmark)

^b BISPEBJERG HOSPITAL   (Denmark)

^c NONE

Author keywords

Bronchodilator; Chronic obstructive pulmonary disease; Device; Inhaler technique; Performance; Tiotropium

Indexed keywords

BETA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; CHOLINERGIC RECEPTOR BLOCKING AGENT; PLACEBO; SALBUTAMOL; SALMETEROL; STEROID; TIOTROPIUM BROMIDE;

ADULT; AGED; ARTICLE; CHRONIC OBSTRUCTIVE LUNG DISEASE; CLINICAL OBSERVATION; CONTROLLED STUDY; DRUG CAPSULE; DRUG DESIGN; DRUG FORMULATION; EQUIPMENT DESIGN; FEMALE; FORCED EXPIRATORY VOLUME; HUMAN; INTERMETHOD COMPARISON; MAJOR CLINICAL STUDY; MALE; METERED DOSE INHALER; PRIORITY JOURNAL; SCORING SYSTEM; TASK PERFORMANCE;

EID: 0141837060     PISSN: 09546111     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0954-6111(03)00162-8     Document Type: Article

References (18)

1. Global initiative for chronic obstructive lung disease (GOLD), Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease (executive summary). National Institutes of Health, 2001.
2. Chodosh S, Flanders JS, Kesten S, Serby CW, et al. Effective delivery of particles with the HandiHaler dry powder inhalation system over a range of chronic obstructive pulmonary disease severity. J Aerosol Med 2001;14:309-15.
3. Casaburi R, Mahler DA, Jones PA, et al. A long-term evaluation of once-daily inhaled tiotropium in chronic obstructive pulmonary disease. Eur Respir J 2002;19:217-24.
4. Vincken W, van Noord JA, Greefhorst APM, et al. Improved health outcomes in patients with COPD during one year treatment with tiotropium. Eur Respir J 2002;19:209-16.
5. Donohue JF, van Noord JA, Bateman ED, et al. A 6-month, placebo-controlled study comparing lung function and health status changes in COPD patients treated with tiotropium or salmeterol. Chest 2002;122:47-55.
6. American Thoracic Society. Standardization of spirometry: 1994 update. Am J Respir Crit Care Med 1995;152:1107-36.
7. Quanjer PH, Tammeling GJ, Cotes JE, et al., Lung volumes and forced ventilatory flows. Report Working Party Standardization of Lung Function Tests, European Community for Steel and Coal. Official Statement of the European Respiratory Society. Eur Respir J Suppl 1993;16:5-40.
8. Fink JB. Metered-dose inhalers, dry powder inhalers, and transitions. Respir Care 2000;45:623-35.
9. Grimwood K, Fergusson DM, Dawson KP. Combination of salbutamol inhalational powder and tablets in asthma. Arch Dis Child 1983;58:283-5.
10. D'Souza S. The Montreal Protocol and essential use exemptions. J Aerosol Med 1995;8(Suppl 1):S13-7.
11. McFadden Jr. ER. Improper patient techniques with metered dose inhalers: clinical consequences and solutions to misuse. J Allergy Clin Immunol 1995;96:278-83.
12. Cain WT, Oppenheimer JJ. The misconception of using floating patterns as an accurate means of measuring the contents of metered-dose inhaler devices. Ann Allergy Asthma Immunol 2001;87:417-9.
13. Kesten S, Elias M, Cartier A, Chapman KR. Patient handling of a multidose dry powder inhalation device for albuterol. Chest 1994;105:1077-81.
14. van Beerendonk I, Mesters I, Mudde AN, Tan TD. Assessment of the inhalation technique in outpatients with asthma or chronic obstructive pulmonary disease using a metered-dose inhaler or dry powder device. J Asthma 1998;35:273-9.
15. Kesten S, Zive K, Chapman KR. Pharmacist knowledge and ability to use inhaled medication delivery systems. Chest 1993;104:1737-42.
16. Liam CK, Lim KH, Wong CM. Acceptance of the Accuhaler, a multi-dose powder inhaler, among asthmatic patients: a comparison with the pressurized metered-dose inhaler. Asian Pac J Allergy Immunol 2000;18:135-40.
17. Cuvelier A, Muir JF, Benhamou D, et al. Dry powder ipratropium bromide is as safe and effective as metered-dose inhaler formulation: a cumulative dose-response study in chronic obstructive pulmonary disease patients. Respir Care 2002;47:159-66.
18. Chopra N, Oprescu N, Fask A, Oppenheimer J. Does introduction of new "easy to use" inhalational devices improve medical personnel's knowledge of their proper use? Ann Allergy Asthma Immunol 2002;88:395-400.