Persistent Mycobacterium avium infection following nonmyeloablative allogeneic peripheral blood stem cell transplantation for interferon-γ receptor-1 deficiency

Blood

Volumn 102, Issue 7, 2003, Pages 2692-2694

  Horwitz, Mitchell E ^a   Uzel, Gulbu ^b   Linton, Gilda F ^b   Miller, Judi A ^b   Brown, Margaret R ^b   Malech, Harry L ^b   Holland, Steven M ^b  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; GAMMA INTERFERON RECEPTOR; INTERFERON GAMMA RECEPTOR 1; UNCLASSIFIED DRUG;

ARTICLE; BONE MARROW CELL; CASE REPORT; CHIMERA; GENE EXPRESSION; HUMAN; HUMAN CELL; IMMUNE DEFICIENCY; INFECTION; INTERFERON GAMMA RECEPTOR 1 DEFICIENCY; MALE; MYCOBACTERIOSIS; MYCOBACTERIUM AVIUM; PERIPHERAL BLOOD STEM CELL; PRESCHOOL CHILD; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

EID: 0141816687     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood-2003-04-1268     Document Type: Article

References (9)

1. Dorman SE, Holland SM. Interferon-gamma and interleukin-12 pathway defects and human disease. Cytokine Growth Factor Rev. 2000;11:321-333.
2. Dorman SE, Uzel G, Roesler J, et al. Viral infections in interferon-gamma receptor deficiency. J Pediatr. 1999;135:640-643.
3. Jouanguy E, Lamhamedi-Cherradi S, Lammas D, et al. A human IFNGR1 small deletion hotspot associated with dominant susceptibility to mycobacterial infection. Nat Genet. 1999;21:370-378.
4. Roesler J, Kofink B, Wendisch J, et al. Listeria monocytogenes and recurrent mycobacterial infections in a child with complete interferon-gamma-receptor (IFNgammaR1) deficiency: mutational analysis and evaluation of therapeutic options. Exp Hematol. 1999;27:1368-1374.
5. Reuter U, Roesler J, Thiede C, et al. Correction of complete interferon-gamma receptor 1 deficiency by bone marrow transplantation. Blood. 2002;100:4234-4235.
6. Holland SM, Dorman SE, Kwon A, et al. Abnormal regulation of interferon-gamma, interleukin-12, and tumor necrosis factor-alpha in human interferon-gamma receptor 1 deficiency. J Infect Dis. 1998;178:1095-1104.
7. Thiede C, Florek M, Bornhauser M, et al. Rapid quantification of mixed chimerism using multiplex amplification of short tandem repeat markers and fluorescence detection. Bone Marrow Transplant. 1999;23:1055-1060.
8. Fleisher TA, Dorman SE, Anderson JA, Vail M, Brown MR, Holland SM. Detection of intracellular phosphorylated STAT-1 by flow cytometry. Clin Immunol. 1999;90:425-430.
9. Hussain S, Zwilling BS, Lafuse WP. Mycobacterium avium infection of mouse macrophages inhibits IFN-gamma Janus kinase-STAT signaling and gene induction by down-regulation of the IFN-gamma receptor. J Immunol. 1999;163:2041-2048.