Synthesis and characterization of hydroxyapatite-ciprofloxacin delivery systems by precipitation and spray drying technique

AAPS PharmSciTech

Volumn 3, Issue 1, 2002, Pages

  Pham, Hai H ^a   Luo, Ping ^b   Génin, François ^b   Dash, Alekha K ^a  

^a CREIGHTON UNIVERSITY   (United States)

^b Berkeley Advanced Biomaterials Inc   (United States)

Author keywords

Agglomerated microspheres; And spray drying; Calcium; Ciprofloxacin; Hydroxyapatite; Implant; Microspheres; Precipitation

Indexed keywords

CIPROFLOXACIN; HYDROXYAPATITE; MICROSPHERE;

ARTICLE; COMPRESSION; CONTROLLED STUDY; DIFFUSION; DRUG DELIVERY SYSTEM; DRUG GRANULATION; DRUG GRANULE; DRUG IMPLANT; DRUG RELEASE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VITRO STUDY; NEBULIZATION; PARTICLE SIZE; POROSITY; PRECIPITATION; SPRAY DRYING; VISCOSITY; BONE INFECTION; CHEMISTRY; DELAYED RELEASE FORMULATION; METHODOLOGY; SYNTHESIS;

BONE DISEASES, INFECTIOUS; CHEMISTRY, PHARMACEUTICAL; CIPROFLOXACIN; DELAYED-ACTION PREPARATIONS; DRUG DELIVERY SYSTEMS; DRUG IMPLANTS; DURAPATITE; MICROSPHERES; PRECIPITATION;

EID: 0141798540     PISSN: 15309932     EISSN: 15309932     Source Type: Journal    
DOI: 10.1208/pt030101     Document Type: Article

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