Informative library design as an efficient strategy to identify and optimize leads: Application to cyclin-dependent kinase 2 antagonists

Journal of Medicinal Chemistry

Volumn 46, Issue 20, 2003, Pages 4360-4364

  Bradley, Erin K ^a,b   Miller, Jennifer L ^a,c   Saiah, Eddine ^a,c   Grootenhuis, Peter D J ^a,d  

^a Deltagen Research Laboratories   (United States)

^b Sunesis Pharmaceuticals Inc   (United States)

^c Kémia ^*  (United States)

^d VERTEX PHARMACEUTICALS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN DEPENDENT KINASE 2; CYCLIN DEPENDENT KINASE 2 INHIBITOR; CYCLIN DEPENDENT KINASE INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; COMBINATORIAL CHEMISTRY; CONFORMATIONAL TRANSITION; MATHEMATICAL COMPUTING; MOLECULAR MODEL;

ALGORITHMS; CDC2-CDC28 KINASES; CHEMISTRY, PHARMACEUTICAL; COMBINATORIAL CHEMISTRY TECHNIQUES; CYCLIN-DEPENDENT KINASE 2; CYCLIN-DEPENDENT KINASES; DATABASES, FACTUAL; DRUG DESIGN; MOLECULAR STRUCTURE; PROTEIN-SERINE-THREONINE KINASES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0141792684     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm020472j     Document Type: Article

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