Cross-resistance to strobilurin fungicides in mitochondrial and nuclear mutants of Saccharomyces cerevisiae

Folia Microbiologica

Volumn 48, Issue 4, 2003, Pages 496-500

  Hnatova M ^a   Gbelska Y ^a   Obernauerova M ^a   Subikova V ^a   Subik J ^a  

^a Physics and Informatics   (Slovakia)

Author keywords

[No Author keywords available]

Indexed keywords

SACCHAROMYCES; SACCHAROMYCES CEREVISIAE;

EID: 0141791045     PISSN: 00155632     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02931331     Document Type: Article

References (24)

1. BALZI E., WANG M., LETERME S., VAN DYCK L., GOFFEAU A.: PDR5, a novel yeast multidrug resistance conferring transporter controlled by the transcription regulator PDR1. J.Biol.Chem. 269, 2206-2214 (1994).
2. BARLETT D.W., CLOUGH J.M., GOLDWIN J.R., HALL A.A., HAMER M., PARR-DOBRZANSKI B.: The strobilurin fungicides. Pest.Manag.Sci. 58, 649-662 (2002).
3. BECKER W.E., VON JAGOW G., ANKE T., STEGLICH W.: Oudemansin, strobilurin A, strobilurin B and myxothiazol: new inhibitors of the bc1 segment of the respiratory chain with an E-β-methoxyacrylate system as common structural element. FEBS Lett. 132, 329-333 (1981).
4. BISSINGER P.H., KUCHLER K.: Molecular cloning and expression of the S. cerevisiae STS1 gene product. J.Biol.Chem. 264, 4180-4186 (1994).
5. CHIN K.M., CHAVAILLAZ D., KAESBOHRER M., STAUB T., FELSENSTEIN F.G.: Characterizing resistance risk of Erysiphe graminis f.sp. tritici to strobilurins. Crop Protect. 20, 87-96 (2001).
6. CLOUGH J.M., GODFREY C.R.A.: The strobilurin fungicides, pp. 109-148 in D.H. Hutson, J. Miyamoto (Eds): Fungicidal Activity. Wiley, Chichester (UK) 1998.
7. DELAVEAU T., DELAHODDE A., CARVAJAL E., ŠUBÍK J., JACQ C.: PDR3, a new yeast regulatory gene, is homologous to PDR1 and controls the multidrug resistance phenomenon. Mol.Gen.Genet. 178, 603-610 (1994).
8. DE RISI J., VAN DEN HAZEL B., MARC P., BALZI E., BROWN P., JACQ C., GOFFEAU A.: Genome microarray analysis of transcriptional activation in multidrug resistance yeast mutants. FEBS Lett. 410, 156-160 (2000).
9. DI RAGO J.P., COPPEE J.Y., COLSON A.M.: Molecular basis for resistance to myxothiazol, mucidin (strobilurin A) and stigmatellin. Cytochrome b inhibitors activity at the center of the mitochondrial ubiquinol-cytochrome-c reductase in Saccharomyces cerevisiae. J.Biol.Chem. 264, 14543-14548 (1989).
10. ESPINEL-INGROFF A., BARCHIESI F., HAZEN K.C., MARTINEZ-SUAREZ J.V., SCALISE G.: Standardization of antifungal susceptibility testing and clinical relevance. Med.Mycol. 36, 68-78 (1998).
11. GISI U., CHIN K.M., KNAPOVA G., KUNG FARBERR R., MOHR U., PARISI S., SIEROTZKI H., STEINFELD U.: Recent developments in elucidated modes of resistance to phenylamide, DMI and strobilurin fungicides. Crop Protect. 19, 863-872 (2000).
12. MICHÁLKOVÁ-PAPAJOVÁ D., OBERNAUEROVÁ M., ŠUBÍK J.: Role of the PDR gene network in yeast susceptibility to the antifungal antibiotic mucidin. Antimicrob.Agents Chemother. 44, 418-420 (2000).
13. MORSCHHAUSER J.: The genetic basis of fluconazole resistance development in Candida albicans. Biochim.Biophys.Acta 1578, 240-248 (2002).
14. NOURANI A., PAPAJOVÁ D., DELAHODDE A., JACQ C., ŠUBÍK J.: Clustered amino acid substitutions in the yeast transcription regulator Pdr3 increase pleiotropic drug resistance and identify a new central regulatory domain. Mol.Gen.Genet. 256, 397-405 (1997).
15. SANGLARD D., KUCHLER K., ISCHER F., PAGANI J.L., MONOD M., BILLE J.: Mechanisms of resistance to azole antifungal agents in Candida albicans isolates from AIDS patients involve specific multidrug transporters. Antimicrob.Agents Chemother. 39, 2378-2386 (1995).
16. SANGLARD D., ISCHER F., MONOD M., BILLE J.: Cloning of Candida albicans genes conferring resistance to azole antifungal agents - characterization of CDR2, a new multidrug ABC transporter gene. Microbiology 143, 405-416 (1997).
17. SANGLARD D., ODDS F.C.: Resistance of Candida species to antifungal agents: molecular mechanisms and clinical consequences. Lancet Infect.Dis. 2, 73-85 (2002).
18. SAUTER H., STEGLICH W., ANKE T.: Strobilurins: evolution of a new class of active substances. Angew.Chem.Internat.Ed. 117, 1328-1349 (1999).
19. ŠUBÍK J., BEHÚŇ M., MUSÍLEK V.: Antibiotic mucidin, a new antimycin A-like inhibitor of electron transport in rat liver mitochondria. Biochem.Biophys.Res.Commun. 57, 17-22 (1974).
20. ŠUBÍK J., KOVÁČOVÁ V., TAKÁCSOVÁ G.: Mucidin resistance in yeast. Isolation, characterization and genetic analysis of nuclear and mitochondrial mucidin-resistant mutants of Saccharomyces cerevisiae. Eur.J.Biochem. 73, 275-286 (1977).
21. ŠUBÍK J., TAKÁCSOVÁ G.: Genetic determination of ubiquinol-cytochrome-c reductase. Mitochondrial locus muc3 specifying resistance of Saccharomyces cerevisiae to mucidin. Mol.Gen.Genet. 161, 99-108 (1978).
22. ŠUBÍK J., ULASZEWSKI S., GOFFEAU A,: Genetic mapping of nuclear mucidin resistance mutations in Saccharomyces cerevisiae. A new pdr locus on chromosome II. Curr.Genet. 10, 665-670 (1986).
23. TAKÁCSOVÁ G., ŠUBÍK J., KOTYLAK Z.: Localization of mucidin-resistant locus muc3 on mitochondrial DNA with respect to ubiquinol-cytochrome-c reductase deficient box loci. Locus muc3 is allelic to box2. Mol.Gen.Genet. 179, 141-146 (1980).
24. THOMPSON J.R., REGISTER E., CUROTTO J., KURTZ M., KELLY R.: An improved protocol for the preparation of yeast cells for transformation by electroporation. Yeast 14, 565-571 (1998).