MRI for the diagnosis of myocardial ischemia and viability

Current Opinion in Cardiology

Volumn 18, Issue 5, 2003, Pages 351-356

  Mankad, Sunil ^a   Khalil, Ramzi ^a   Kramer, Christopher M ^b  

^a ALLEGHENY GENERAL HOSPITAL   (United States)

^b UNIVERSITY OF VIRGINIA HEALTH SYSTEM   (United States)

Author keywords

Ischemia; Magnetic resonance; Viability

Indexed keywords

DOBUTAMINE; FLUORODEOXYGLUCOSE F 18;

CELL VIABILITY; CLINICAL TRIAL; COMPUTER ASSISTED EMISSION TOMOGRAPHY; CORONARY ARTERY DISEASE; DIAGNOSTIC TEST; EVALUATION; HEART MUSCLE CONTRACTILE FORCE; HEART MUSCLE ISCHEMIA; HEART MUSCLE PERFUSION; HUMAN; LOW DRUG DOSE; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; REVIEW; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY;

ACUTE DISEASE; DIAGNOSTIC IMAGING; DOBUTAMINE; EXERCISE TEST; HUMANS; MAGNETIC RESONANCE IMAGING; MYOCARDIAL ISCHEMIA; MYOCARDIAL REPERFUSION; MYOCARDIUM; PROGNOSIS;

EID: 0141788072     PISSN: 02684705     EISSN: None     Source Type: Journal    
DOI: 10.1097/00001573-200309000-00005     Document Type: Review

References (29)

1. Martin ET, Fuisz AR, Pohost GM: Imaging cardiac structure and pump function. Cardiol Clin 1998, 16:135-160.
2. Nagel E, Lehmkuhl HB, Bocksch W, et al.: Noninvasive diagnosis of ischemia-induced wall motion abnormalities with the use of high-dose dobutamine stress echocardiography. Comparison with dobutamine stress echocardiography. Circulation 1999, 99:763-770.
3. Hundley EG, Hamilton CA, Thomas MS, et al.: Utility of fast cine magnetic resonance imaging and display for the detection of myocardial ischemia in patients not well suited for second harmonic stress echocardiography. Circulation 1999, 100:1697-1702.
4. Hundley WG, Morgan TM, Neagle CM, et al.: Magnetic resonance imaging determination of cardiac prognosis. Circulation 2002, 106:2328-2333. This is an important study illustrating the ability of DMRI to provide prognostic information in a group of patients with nondiagnostic DSE studies.
5. Kuijpers D, Ho KYJAM, van Dijkman PRM, et al.: Dobutamine cardiovascular magnetic resonance for the detection of myocardial ischemia with the use of myocardial tagging. Circulation 2003, 107:1592-1597. This paper uses state-of-the-art MRI techniques for the global and regional assessment of myocardial ischemia and also provides data on the use of CMRI for risk stratification of future cardiovascular events.
6. Zerhouni EA, Parish DM, Rogers WJ, et al.: Human heart: tagging with MR imaging: a method for noninvasive assessment of myocardial motion. Radiology 1988, 169:59-63.
7. Rerkpattanapipat P, Morgan TM, Neagle CM, et al.: Assessment of preoperative cardiac risk with magnetic resonance imaging. Am J Cardiol 2002, 90:416-419. This well-designed study illustrates the utility of DMRI in risk stratifying patients at intermediate clinical risk for cardiac events who are undergoing noncardiac surgery.
8. Al-Saadi N, Nagel E, Gross M, et al.: Noninvasive detection of myocardial ischemia from perfusion reserve based on cardiovascular magnetic resonance. Circulation 2000, 101:1379-1383.
9. Schwitter J, Nanz D, Kneifel S, et al.: Assessment of myocardial perfusion in coronary artery disease by magnetic resonance: a comparison with positron emission tomography and coronary angiography. Circulation 2001, 103:2230-2235.
10. Panting JR, Gatehouse PD, Yang G-Z, et al.: Abnormal subendocardial perfusion in cardiac syndrome X detected by cardiovascular magnetic resonance imaging. N Engl J Med 2002, 346:1948-1953. This study illustrates the superior temporal resolution of cardiac MRI and how differences in subendocardial and subepicardial regions can be evaluated to demonstrate myocardial ischemia in patients with syndrome X.
11. Buchthal SD, den Hollander JA, Merz NB, et al.: Abnormal myocardial phosphorus-31 nuclear magnetic resonance spectroscopy in women with chest pain by normal coronary angiograms. N Engl J Med 2000, 342:829-835.
12. Kwong RY, Schussheim AE, Rekhraj S, et al.: Detecting acute coronary syndrome in emergency department with cardiac magnetic resonance imaging. Circulation 2003, 107:531-537. This paper incorporates multiple cardiac MRI modalities in the emergency room treatment of chest pain and demonstrated that MRI identified a high fraction of patients with acute coronary syndrome.
13. Kloner RA, Bolli R, Marban E, et al.: Medical and cellular implications of stunning, hibernation, and preconditioning. An NHLBI Workshop. Circulation 1998, 97:1848-1867.
14. 18F]-fluorodeoxyglucose in patients with chronic coronary artery disease. Circulation 1995, 81:1006-1015.
15. Baer FM, Thiessen P, Schneider CA, et al.: Dobutamine magnetic resonance imaging predicts contractile recovery of chronically dysfunctional myocardium after successful revascularization. J Am Coll Cardiol 1998, 31:1040-1048.
16. Sayad DE, Willett DL, Hundley WG, et al.: Dobutamine magnetic resonance imaging with myocardial tagging quantitatively predicts improvement in regional function after revascularization. Am J Cardiol 1998, 82:1149-1151.
17. Geskin G, Kramer CM, Rogers WJ, et al.: Quantitative assessment of myocardial viability after infarction by dobutamine magnetic resonance tagging. Circulation 1998, 98:217-233.
18. Kramer CM, Malkowski MJ, Mankad S, et al.: Magnetic resonance tagging and echocardiographic response to dobutamine and functional improvement after reperfused myocardial infarction. Am Heart J 2002, 143:1046-1051. This study directly compared tagged DMRI with DSE in the assessment of myocardial viability as assessed by recovery of myocardial function in patients after reperfused myocardial infarction.
19. Zamorano J, Delgado J, Almeria C, et al.: Reason for discrepancies in identifying myocardial viability by thallium-201 redistribution, magnetic resonance imaging, and dobutamine echocardiography. Am J Cardiol 2002, 90:455-459. This study compared DMRI, DSE, and thallium-201 redistribution imaging for the assessment of myocardial viability as assessed pathologically in heads explanted from patients with ischemic cardiomyopathy undergoing heart transplantation.
20. Kramer CM, Rogers WJ, Mankad S, et al.: Contractile reserve and contrast uptake pattern by magnetic resonance imaging and functional recovery after reperfused myocardial infarction. J Am Coll Cardiol 2000, 36:1835-1840.
21. Rogers WJ, Kramer CM, Geskin G, et al.: Early contrast-enhanced MRI predicts late functional recovery after reperfused myocardial infarction. Circulation 1999, 99:744-750.
22. Kim RJ, Fiens DS, Parrish TB: Relationship of MRI delayed contrast enhancement to irreversible injury, infarct age, and contractile function. Circulation 1999,100:1992-2002.
23. Wu E, Judd RM, Vargas JD, et al.: Visualisation of presence, location, and transmural extent of healed Q-wave and non-Q-wave myocardial infarction. Lancet 2001, 357:21-28.
24. Kim RJ, Wu E, Rafael A, et al.: The use of contrast-enhanced magnetic resonance imaging to identify reversible myocardial dysfunction. N Engl J Med 2000, 343:1445-1453.
25. Fieno DS, Kim RJ, Chen E-L, et al: Contrast-enhanced magnetic resonance imaging of myocardium at risk. Distinction between reversible and irreversible injury through infarct healing. J Am Coll Cardiol 2000, 36:1985-1991.
26. Ramani K, Judd RM, Holly TA, et al.: Contrast magnetic resonance imaging in the assessment of myocardial viability in patients with stable coronary artery disease and left ventricular dysfunction. Circulation 1998, 98:2687-2694.
27. Gerber BL, Garot J, Bluemke DA, et al: Accuracy of contrast-enhanced magnetic resonance imaging in predicting improvement of regional myocardial function in patients after acute myocardial infarction. Circulation 2002, 106:1083-1089. This study looked at contrast-enhanced MRI after myocardial infarction and identified the patterns of early and delayed uptake that were associated with myocardial viability.
28. Wagner A, Mahrholdt H, Holly TA, et al.: Contrast-enhanced MRI and routine single photon emission computed tomography (SPECT) perfusion imaging for detection of subendocardial myocardial infarcts: an imaging study. Lancet 2003, 361:374-379. This study illustrates the superior ability of contrast MRI to detect smaller subendocardial myocardial infarcts compared with SPECT.
29. Klein C, Nekolla SG, Bengel FM, et al.: Assessment of myocardial viability with contrast-enhanced magnetic resonance imaging. Comparison with positron emission tomography. Circulation 2002, 105:162-167. This recent paper compared perfusion MRI directly with PET for the assessment of myocardial viability and found close agreement but superior spatial resolution with MRI.