Differential recognition of Plasmodium falciparum merozoite surface protein 2 variants by antibodies from malaria patients in Brazil

Clinical and Diagnostic Laboratory Immunology

Volumn 10, Issue 5, 2003, Pages 973-976

  Kanunfre, Kelly A ^a   Leoratti, Fabiana M S ^a   Hoffmann, Erika H E ^a   Durlacher, Rui R ^a,b   Ferreira, Antônio W ^a   Moraes Ávila, Sandra L ^a   Ferreira, Marcelo U ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b Center for Research in Tropical Medicine   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; MEFLOQUINE; MEROZOITE SURFACE PROTEIN 2;

ADULT; ANTIBODY RESPONSE; ARTICLE; BRAZIL; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSS REACTION; HUMAN; IMMUNE RESPONSE; IMMUNITY; MAJOR CLINICAL STUDY; MALARIA; MALE; MEROZOITE; NUCLEOTIDE SEQUENCE; PATHOGENESIS; PLASMODIUM FALCIPARUM; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL;

EID: 0141787128     PISSN: 1071412X     EISSN: None     Source Type: Journal    
DOI: 10.1128/CDLI.10.5.973-976.2003     Document Type: Article

References (13)

1. Al-Yaman, F., B. Genton, R. F. Anders, M. Falk, T. Triglia, D. Lewis, J. Hii, H.-P. Beck, and M. P. Alpers. 1994. Relationship between humoral response to Plasmodium falciparum merozoite surface antigen-2 and malaria morbidity in a highly endemic area of Papua New Guinea. Am. J. Trop. Med. Hyg. 51:593-602.
2. Berzins, K., and R. F. Anders. 1999. The malaría antigens, p. 181-216. In M. Wahlgren and P. Perlmann (ed.), Malaria - molecular and clinical aspects. Harwood Academic Publishers, Amsterdam, The Netherlands.
3. Cerutti, C., Jr., R. R. Durlacher, F. E. C. de Alencar, A. A. C. Segurado, and L. W. Pang. 1999. In vivo efficacy of mefloquine for the treatment of falciparum malaria in Brazil. J. Infect. Dis. 180:2077-2080.
4. da Silveira, L. A., M. L. Dorta, E. A. S. Kimura, A. M. Katzin, F. Kawamoto, K. Tanabe, and M. U. Ferreira. 1999. Allelic diversity and antibody recognition of Plasmodium falciparum merozoite surface protein 1 during hypoendemic malaria transmission in the Brazilian Amazon region. Infect. Immun. 67:5906-5916.
5. Fenton, B., J. T. Clark, A. Khan, V. J. Robinson, D. Walliker, R. Ridley, J. G. Scaife, and J. S. McBride. 1991. Structural and antigenic polymorphism of the 35- to 48-kilodalton merozoite surface antigen (MSA-2) of the malaria parasite Plasmodium falciparum. Mol. Cell. Biol. 11:963-971.
6. Ferreira, M. U., Q. Liu, O. Kaneko, M. Kimura, K. Tanabe, E. A. S. Kimura, A. M. Katzin, S. Isomura, and F. Kawamoto. 1998. Allelic diversity at the merozoite surface protein-1 locus of Plasmodium falciparum in clinical isolates from the southwestern Brazilian Amazon. Am. J. Trop. Med. Hyg. 59:474-480.
7. Hoffmann, E. H. E., L. A. Silveira, R. Tonhosolo, F. J. T. Pereira, W. L. Ribeiro, A. P. Tonon, F. Kawamoto, and M. U. Ferreira. 2001. Geographical patterns of allelic diversity in the Plasmodium falciparum malaria-vaccine candidate, merozoite surface protein-2. Ann. Trop. Med. Parasitol. 95:117-132.
8. McKenzie, F. E., M. U. Ferreira, J. K. Baird, G. Snounou, and W. H. Bossert. 2001, Meiotic recombination, cross-reactivity, and persistence in Plasmodium falciparum. Evol. Int. J. Org. Evol. 55:1299-1307.
9. Ranford-Cartwright, L. C., R. R. Taylor, N. Asfari-Jirhandeh, D. B. Smith, P. E. Roberts, V. J. Robinson, H. A. Babiker, E. M. Riley, D. Walliker, and J. S. McBride. 1996. Differential antibody recognition of FC27-like Plasmodium falciparum merozoite surface protein MSP2 antigens which lack 12 amino acid repeats. Parasite Immunol. 18:411-420.
10. Rich, S. M., M. U. Ferreira, and F. J. Ayala. 2000. The origin of antigenic diversity in Plasmodium falciparum. Parasitol. Today 16:390-396.
11. Taylor, R. R., D. B. Smith, V. J. Robinson, J. S. McBride, and E. M. Riley. 1995. Human antibody response to Plasmodium falciparum merozoite surface protein 2 is subgroup specific and predominantly of the immunoglobulin G3 subclass. Infect. Immun. 63:4382-4388.
12. Taylor, R. R., S. J. Allen, B. M. Greenwood, and E. M. Riley. 1998. IgG3 antibodies to Plasmodium falciparum merozoite surface protein 2 (MSP-2): increasing prevalence with age and association with clinical immunity to malaria. Am. J. Trop. Med. Hyg. 58:406-413.
13. Tonhosolo, R., G. Wunderlich, and M. U. Ferreira. 2001. Differential antibody recognition of four allelic variants of the merozoite surface protein-2 (MSP-2) of Plasmodium falciparum. J. Eukaryot. Microbiol. 48:556-564.