Primary cutaneous melanoma: surgical management and other treatment options

Current Treatment Options in Oncology

Volumn 4, Issue 3, 2003, Pages 177-185

  Wagner, Jeffrey D ^a   Bergman, Debra ^b  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NONE

Author keywords

Cutaneous Melanoma; Melanoma; Primary Melanoma; Sentinel Node Biopsy; Tumor Thickness

Indexed keywords

ADJUVANT CHEMOTHERAPY; ADJUVANT THERAPY; CLINICAL TRIAL; DISEASE FREE SURVIVAL; HUMAN; MELANOMA; METASTASIS; PATHOLOGY; REVIEW; SKIN TUMOR; TUMOR RECURRENCE;

CHEMOTHERAPY, ADJUVANT; CLINICAL TRIALS; DISEASE-FREE SURVIVAL; HUMANS; MELANOMA; NEOPLASM METASTASIS; NEOPLASM RECURRENCE, LOCAL; RADIOTHERAPY, ADJUVANT; SKIN NEOPLASMS;

EID: 0141784083     PISSN: 15272729     EISSN: 15346277     Source Type: Journal    
DOI: 10.1007/s11864-003-0019-6     Document Type: Article

References (31)

1. Howe HL, Wingo PA, Thun MJ, et al.: Annual report to the nation on the status of cancer (1973 through 1998), featuring cancers with recent increasing trends. J Natl Cancer Inst 2001, 93:824–842. DOI: 10.1093/jnci/93.11.824
2. Geller AC, Miller DR, Annas GD, et al.: Melanoma incidence and mortality among US whites, 1969–1999. JAMA 2002, 288:1719–1720. This paper shows the recent trends in melanoma incidence and mortality among whites in the United States. DOI: 10.1001/jama.288.14.1719
3. Rigel DS, Friedman RJ, Kopf AW: The incidence of malignant melanoma in the United States: issues as we approach the 21st century. J Am Acad Dermatol 1996, 34:839–847. DOI: 10.1016/S0190-9622(96)90041-9
4. Balch CM, Buzaid AC, Soong SJ, et al.: Final version of the American Joint Committee on Cancer staging system for cutaneous melanoma. J Clin Oncol 2001, 19:3635–3648. This article illustrates the most recent AJCC melanoma staging system and describes the most pertinent prognostic indicators in melanoma.
5. Handley WS: The pathology of melanotic growths in relation to their operative treatment. Lancet 1907, 1:927.
6. Breslow A, Macht SD: Optimal size of resection margin for thin cutaneous melanoma. Surg Gynecol Obstet 1977, 145:691–692.
7. Elder DE, Guerry D, Heiberger RM, et al.: Optimal resection margins for cutaneous malignant melanoma. Plast Reconstr Surg 1983, 71:66–72.
8. Goldman LI, Byrd R: Narrowing resection margins for patients with low-risk melanoma. Am J Surg 1988, 155:242–44.
9. Day CL, Mihm MC, Sober AJ, et al.: Narrower margins for clinical stage I malignant melanoma. N Eng J Med 1982, 306:479–482. DOI: 10.1056/NEJM198202253060810
10. Soong SJ, Weiss HL: Predicting outcome in patients with localized melanoma. In Cutaneous Melanoma. Edited by Balch CM, Houghton AN, Sober AJ, Soong SJ. St. Louis: Quality Medical Publishing; 1998:51–61.
11. Balch CM, Buzaid AC, Atkins MB, et al.: A new American Joint Committee on Cancer staging system for cutaneous melanoma. Cancer 2000, 88:1484–1491. DOI: 10.1002/(SICI)1097-0142(20000315)88:6<1484::AID-CNCR29>3.0.CO;2-D
12. Gershenwald JE, Thompson W, Mansfield PF, et al.: Multi-institutional melanoma lymphatic mapping experience: the prognostic value of sentinel lymph node status in 612 stage I or II melanoma patients. J Clin Oncol 1999, 17:976–983. This article illustrates the primary prognostic importance of sentinel node status in patients with stage I and II melanoma.
13. Wagner JD, Gordon MS, Chuang TY, et al.: Current therapy of cutaneous melanoma. Plast Reconstr Surg 2000, 105:1774–1799. DOI: 10.1097/00006534-200004050-00028
14. NIH consensus conference. Diagnosis and treatment of early melanoma. JAMA 1992, 268:1314–1319. This article discusses the consensus of opinions for treatment of patients with low-risk primary melanomas.
15. Veronesi U, Cascinelli N, Adamus J, et al.: Thin stage I primary cutaneous malignant melanoma: comparison of excision with margins of 1 or 3cm. N Engl J Med 1988, 318:1159–1162. The article provides the primary scientific foundation on which treatment of melanomas up to 2 mm deep is based. DOI: 10.1056/NEJM198805053181804
16. Balch CM, Urist MM, Karakousis CP, et al.: Efficacy of 2-cm surgical margins for intermediate thickness melanomas (1 to 4 mm): results of a multi-institutional randomized surgical trial. Ann Surg 1993, 218:262–69. This article provides the primary scientific basis for the treatment of intermediate-thickness melanoma 1 to 4 mm deep. DOI: 10.1097/00000658-199309000-00005
17. Ringborg U, Andersson R, Eldh J, et al.: Resection margins of 2 versus 5 cm for cutaneous malignant melanoma with a tumor thickness of 0.8 to 2.0 mm: randomized study by the Swedish melanoma study group. Cancer 1996, 77:1809–1814. DOI: 10.1002/(SICI)1097-0142(19960501)77:9<1809::AID-CNCR8>3.0.CO;2-6
18. Ross MI, Balch CM: Surgical treatment of primary melanoma. In Cutaneous Melanoma. Edited by Balch CM, Houghton AN, Sober AJ, Soong SJ. St. Louis: Quality Medical Publishing; 1998:141–153.
19. Thomas JM, Newton-Bishop JA, Timmons M, et al.: Surgical margin excision width in high risk (minimum depth 2 mm) cutaneous malignant melanoma: a randomized trial of 1 cm versus 3 cm margins in 900 patients [abstract]. Prog Proc Am Soc Clin Oncol 2002, 21:340. This abstract describes the largest melanoma excision trial that is the only trial to include melanomas greater than 4 mm deep. It is also the only trial to show a disadvantage for narrower margins of excision.
20. Gershenwald JE, Colome ME, Lee JE, et al.: Patterns of recurrence following a negative sentinel lymph node biopsy in 243 patients with stage I or II melanoma. J Clin Oncol 1998, 16:2253–2260.
21. Clary BM, Mann B, Brady MS, et al.: Early recurrence after lymphatic mapping and sentinel node biopsy in patients with primary extremity melanoma: a comparison with elective lymph node dissection. Ann Surg Oncol 2001, 8:328–337. DOI: 10.1007/s10434-001-0328-6
22. Cooper PH, Mills SE, Allen MS Jr: Malignant melanoma of the anus. Report of 12 patients and analysis of 255 additional cases. Dis Colon Rectum 1982, 25:693–703. DOI: 10.1007/BF02629543
23. Brady MS, Kavolius JP, Quan SH: Anorectal melanoma. A 64-year experience at Memorial Sloan-Kettering Cancer Center. Dis Colon Rectum 1995, 38:146–151. DOI: 10.1007/BF02052442
24. Ballo MT, Gershenwald JE, Gunar K, et al.: Sphinctersparing local excision and adjuvant radiation for analrectal melanoma. J Clin Oncol 2002, 20:4555–4558. DOI: 10.1200/JCO.2002.03.002
25. Cascinelli N, Belli F, Santinami M, et al.: Sentinel lymph node biopsy in cutaneous melanoma: the WHO melanoma program experience. Ann Surg Oncol 2000, 7:469–474. This article illustrates the use of SNB for staging patients with early stage melanoma. DOI: 10.1007/s10434-000-0469-z
26. Wagner JD, Gordon MS, Chuang TY, et al.: Predicting sentinel and residual lymph node basin disease after sentinel lymph node biopsy for melanoma. Cancer 2000, 89:453–462. DOI: 10.1002/1097-0142(20000715)89:2<453::AID-CNCR34>3.0.CO;2-V
27. Zitelli JA, Brown CD, Hanusa BH: Surgical margins for excision of primary cutaneous melanoma. J Am Acad Dermatol 1997, 37:422–429. This article shows the extent of surgical margins of excision necessary to achieve histologically clear margins in patients with melanoma. DOI: 10.1016/S0190-9622(97)70144-0
28. Zitelli JA, Brown C, Hanusa BH: Mohs micrographic surgery for the treatment of primary cutaneous melanoma. J Am Acad Dermatol 1997, 37:236–245. This article describes a nonrandomized trial showing the possible applicability of MMS for patients with melanoma. DOI: 10.1016/S0190-9622(97)80131-4
29. Albertini JG, Elston DM, Libow LF, et al.: Mohs micrographic surgery for melanoma: a case series, a comparative study of immunostains, an informative case report, and a unique mapping technique. Dermatol Surg 2002, 28:656–663. DOI: 10.1046/j.1524-4725.2002.02024.x
30. Anderson TD, Weber RS, Dupont G, et al.: Desmoplastic neurotropic melanoma of the head and neck: the role of radiation therapy. Head Neck 2002, 24:1068–1071. DOI: 10.1002/hed.10141
31. Demierre M, Nathanson L: Chemoprevention of melanoma: an unexplored strategy. J Clin Oncol 2003, 21:158–165. DOI: 10.1200/JCO.2003.07.173