5′-O-fluorosulfonylbenzoyl esters of purine nucleosides as potential inhibitors of NTPase/helicase and polymerase of Flaviviridae viruses

Nucleosides, Nucleotides and Nucleic Acids

Volumn 22, Issue 5-8, 2003, Pages 1531-1533

  Bretner, M ^a   Schalinski, S ^b   Borowski, P ^b   Kulikowski, T ^a  

^a INSTITUTE OF BIOCHEMISTRY AND BIOPHYSICS   (Poland)

^b BERNHARD NOCHT INSTITUTE FOR TROPICAL MEDICINE   (Germany)

Author keywords

5 O (4 fluorosulfonylbenzoyl) adenosine (FSBA); Flaviviridae analogue

Indexed keywords

5' O (4 FLUOROSULFONYLBENZOYL)ADENOSINE; 5' O FLUOROSULFONYLBENZOYL ESTER; ADENOSINE DERIVATIVE; DNA POLYMERASE; ENZYME INHIBITOR; ESTER; GUANOSINE DERIVATIVE; HELICASE; INOSINE DERIVATIVE; PURINE NUCLEOSIDE; RIBAVIRIN DERIVATIVE; UNCLASSIFIED DRUG; NUCLEOSIDE TRIPHOSPHATASE; PURINE DERIVATIVE;

CONFERENCE PAPER; FLAVIVIRUS; HEPATITIS C VIRUS; MOLECULAR INTERACTION; SYNTHESIS; ARTICLE; DRUG ANTAGONISM; ENZYMOLOGY;

FLAVIVIRIDAE; FLAVIVIRUS; HEPATITIS C VIRUS;

DNA HELICASES; ENZYME INHIBITORS; FLAVIVIRIDAE; NUCLEOSIDE-TRIPHOSPHATASE; PURINE NUCLEOSIDES; PURINES;

EID: 0141707907     PISSN: 15257770     EISSN: None     Source Type: Journal    
DOI: 10.1081/NCN-120023027     Document Type: Conference Paper

References (4)

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2. Kyono, K.; Miyashiro, M.; Taguchi, I. Detection of hepatitis C virus helicase activity using the scintilation proximity assay system. Anal. Biochem. 1998, 257, 120-126.
3. Borowski, P.; Mueller, O.; Niebuhr, A.; Kalitzky, M.; Hwang, L-H.; Schmitz, H.; Siwecka, A.M.; Kulikowski, T. ATP-binding domain of NTPase/ helicase as a target for hepatitis C antiviral therapy. Acta Biochim. Pol. 2000, 47, 173-180; Borowski, P.; Niebuhr, A.; Mueller, O.; Bretner, M.; Felczak, K.; Kulikowski, T.; Schmitz, H. Purification and characterization of West Nile Virus Nucleoside triphosphatase (NTPase/helicase: evidence for dissociation of the NTPase and helicase activities of the enzyme). J. Virol. 2001, 75, 3220-3229.
4. Borowski, P.; Mueller, O.; Niebuhr, A.; Kalitzky, M.; Hwang, L-H.; Schmitz, H.; Siwecka, A.M.; Kulikowski, T. ATP-binding domain of NTPase/ helicase as a target for hepatitis C antiviral therapy. Acta Biochim. Pol. 2000, 47, 173-180; Borowski, P.; Niebuhr, A.; Mueller, O.; Bretner, M.; Felczak, K.; Kulikowski, T.; Schmitz, H. Purification and characterization of West Nile Virus Nucleoside triphosphatase (NTPase/helicase: evidence for dissociation of the NTPase and helicase activities of the enzyme). J. Virol. 2001, 75, 3220-3229.