Simultaneous bindings of uPA and latent TGF-β for the activation of latent TGF-β in homotypic smooth muscle cells

Tohoku Journal of Experimental Medicine

Volumn 179, Issue 1, 1996, Pages 23-34

  Abe, Hiroko ^a   Abe, Mayumi ^b   Tanaka, Katsuhiro ^b   Iwasaka, Chika ^b   Sato, Yasufumi ^b  

^a OITA UNIVERSITY   (Japan)

^b TOHOKU UNIVERSITY   (Japan)

Author keywords

Activation; Latent TGF ; Smoth muscle cell; uPA; uPA receptor

Indexed keywords

EID: 0141702494     PISSN: 00408727     EISSN: None     Source Type: Journal    
DOI: 10.1620/tjem.179.23     Document Type: Article

References (40)

1. Antonelli-Orlidge, A.A., Saunders, K.B., Smith, S.R. & D'Amore, P.A. (1989) An activated form of transforming growth factor-β is produced by cocultures of endothelial cells and pericytes. Proc. Natl. Acad. Sci. USA, 86, 4544-4548.
2. Battegay, E.J., Raines, E.W., Seifert, R.A., Bowen-Pope, D.F. & Ross, R. (1990) TGF-β induces bimodal proliferation of connective tissue cells via complex control of an autocrine PDGF loop. Cell, 63, 515-524.
3. Blasi, F. (1993) Urokinase and urokinase receptor: A paracrine/autocrine system regulating cell migration and invasiveness. Bioessays, 15, 105-111.
4. Bristol, L.A., Ruscetti, F.W., Brody, D.T. & Durum, S.K. (1990) IL-1α- induces expression of active transforming growth factor-β in nonproliferating T cells via a post-transcriptional mechanism. J. Immunol., 145, 4108-4114.
5. Colletta, A.A., Wakefield, L.M., Howell, F.V., van Roozendaal, K.E.P., Danielpour, D., Ebbs, S.R., Sporn, M.B. & Baum, M. (1990) Anti-oestorongens induce the secretion of active transforming growth factor beta from human fetal fibroblasts. Br. J. Cancer, 60, 405-409.
6. Flaumenhaft, R., Abe, M., Mignatti, P. & Rifkin, D.B. (1992) Basic fibroblast growth factor-induced activation of latent transforming growth factor β in endothelial cells: Regulation of plasminogen activator activity. J. Cell Biol., 118, 901-909.
7. Flaumenhaft, R., Abe, M., Sato, Y., Miyazono, K., Harpel, J., Heldin, C.-H. & Rifkin, D.B. (1993) Role of the latent TGF-β binding protein in the activation of latent TGF-β by co-cultures of endothelial and smooth muscle cells. J. Cell Biol., 120, 995-1002.
8. Gibbons, G.H., Pratt, R.E. & Dzau, V.J. (1992) Vascular smooth muscle cell hypertrophy vs. hyperplasia. J. Clin. Invest., 90, 456-461.
9. Glick, A.B., Flanders, K.C., Danielpour, D., Yuspa, S.H. & Sporn, M.B. (1989) Retinoic acid induces transforming growth factor-β2 in cultured keratinocytes and mouse epidermis. Cell Regul., 1, 87-97.
10. Grainger, D.J., Weissberg, P.L. & Metcalfe, J.C. (1993a) Tamoxifen decreases the rate of proliferation of rat vascular smooth-muscle cells in culture by inducing production of transforming growth factor β. Biochem. J., 294, 109-112.
11. Grainger, D.J., Kirschenlohr, H.L., Metcalfe, J.C., Weissberg, P.L., Wade, D.P. & Lawn, R.M. (1993b) Proliferation of human smooth muscle cells promoted lipoprotein(a). Science, 260, 1655-1658.
12. Grainger, D.J., Kemp, P.R., Liu, A.C., Lawn, R.M. & Metcalfe, J.C. (1994) Activation of transforming growth factor-β is inhibited in transgenic apolipoprotein(a) mice. Nature, 370, 460-462.
13. Huber, D., Philipp, J. & Fontana, A. (1992) Protease inhibitors interfere with the transforming growth factor-β-dependent but not the transforming growth factor-β-independent pathway of tumor cell-mediated immunosuppression. J. Immunol., 148, 277-284.
14. Kanzaki, T., Olofsson, A., Moren, A., Wernstedt, C., Hellman, U., Miyazono, K., Claesson-Welsh, L. & Heldin, C.-H. (1990) TGF-β1 binding protein: A component of the large latent complex of TGF-β1 with multiple repeat sequences. Oell, 61, 1051-1061.
15. Kojima, S. & Rifkin, D.B. (1993) Mechanism of retinoid-induced activation of latent transforming growth factor-β in bovine endothelial cells. J. Cell. Physiol., 155, 323-332.
16. Kojima, S., Harpel, P.C. & Rifkin, D.B. (1991) Lipoprotein(a) inhibits the generation of transforming growth factor β: An endogenous inhibitor of smooth muscle cell migration. J. Cell Biol., 113, 1439-1445.
17. Lyons, R.M., Gentry, L.E., Purchio, A.F. & Moses, H.L. (1990) Mechanism of activation of latent recombinant transforming growth factor-β1 by plasmin. J. Cell Biol., 110, 1361-1367.
18. Majesky, M.W., Lindner, V., Twardzik, D.R., Shwartz, S.M. & Reidy, M.A. (1991) Production of transforming growth factor β1 during repair of arterial injury. J. Clin. Invest., 88, 904-910.
19. Miyazono, K., Hellman, U., Wernstedt, C. & Heldin, C.-H. (1988) Latent high molecular weight complex of transforming growth factor β1. J. Biol. Chem., 263, 6407-6415.
20. Miyazono, K., Olofsson, A., Colosetti, P. & Heldin, C.-H. (1991) A role of the latent TGF-β1 binding protein in the assembly and secretion of TGF-β1. EMBO J., 10, 1091-1101.
21. Nabel, E.G., Shum, L., Pompili, V.J., Yang, Z.-Y., San, H., Shu, H.B., Liptay, S., Gold, L., Gordon, D., Derynck, R. & Nabel, G.J. (1993) Direct transfer of transforming growth factor β1 gene into arteries stimulates fibrocellular hyperplasia. Proc. Natl. Acad. Sci. USA, 90, 10759-10763.
22. Nikol, S., Isner, J.M., Pickering, J.G., Kearney, M., Leclerc, G. & Weir, L. (1992) Expression of transforming growth factor-β1 is increased in human vascular restenosis lesions. J. Clin. Invest., 90, 1582-1592.
23. Noda-Heiny, H., Daugherty, A. & Sobel, B.E. (1995) Augmented urokinase receptor expression in atheroma. Arterioscler. Thromb. Vase. Biol., 15, 37-43.
24. Odekon, L.E., Blasi, F. & Rifkin, D.B. (1994) Requirement for receptor-bound urokinase in plasmin-dependent cellular conversion of latent TGF-β to TGF-β. J. Cell. Physiol., 158, 398-407.
25. Okada, S.S., Tomaszewski, J.E. & Barnathan, E.S. (1995) Migrating vascular smooth muscle cells polarize cell surface urokinase receptors after injury in vitro. Exp. Cell Res., 217, 180-187.
26. Oreffo, R.O.C., Mundy, G.R., Seydin, S.M. & Bonewald, L.F. (1989) Activation of the bone-derived latent TGF beta complex by isolated osteoclasts. Biochem. Biophys. Res. Commun., 158, 817-823.
27. Oursler, M.J., Riggs, B.L. & Spelsberg, T.C. (1993) Glucocorticoid-induced activation of latent transforming growth factor-β by normal human osteoblast-like cells. Endocrinology, 133, 2187-2196.
28. Piao, Y.-F., Ichijo, H., Miyagawa, K., Ohashi, H., Takaku, F. & Miyazono, K. (1990) Latent form of transforming growth factor-β1 acts as a potent growth inhibitor on a human erythroleukemia cell line. Biochem. Biophys. Res. Commun., 167, 27-32.
29. Pircher, R., Lawrence, D.A. & Jullien, P. (1984) Latent β-transforming growth factor in nontransformed and Kirsten sarcoma virus-transformed normal rat kidney cells, clone 49F. Cancer Res., 44, 5538-5543.
30. Sakuda, H., Nakashima, Y., Kuriyama, S. & Sueishi, K. (1992) Media conditioned by smooth muscle cells cultured in a variety of hypoxic environments stimulates in vitro angiogenesis. A relationship to transforming growth factor-β1. Am. J. Pathol., 141, 1507-1516.
31. Sato, Y, & Rifkin, D.E. (1989) Inhibition of endothelial cell movement by pericytes and smooth muscle cells. Activation of a latent transforming growth factor-β1-like molecule by plasmin during co-culture. J. Cell Biol., 109, 309-315.
32. Sato, Y., Tsuboi, R., Lyons, R., Moses, H. & Rifkin, D.B. (1990) Characterization of the activation of latent TGF-β by co-cultures of endothelial cells and pericytes or smooth muscle cells: A self-regulating system. J. Cell Biol., 111, 757-763.
33. Sato, Y., Okada, F., Abe, M., Seguchi, T., Kuwano, M., Sato, S., Furuya, A., Hanai, N. & Tamaoki, T. (1993) The mechanism for the activation of latent TGF-β during co-culture of endothelial cells and smooth muscle cells: Cell-type specific targeting of latent TGF-β to smooth muscle cells. J. Cell Biol, 123, 1249-1254.
34. Takiuchi, H., Tada, T., Li, X.-F., Ogata, M., Ikeda, T., Fujimoto, S., Fujiwara, H. & Hamaoka, T. (1992) Particular types of tumor cells have the capacity to convert transforming growth factor β from a latent to an active form. Cancer Res., 52, 5641-5646.
35. Tsuji, T., Okada, F., Yamaguchi, K. & Nakamura, T. (1990) Molecular cloning of the large subunit of transforming growth factor type β masking protein and expression of the mRNA in various tissues. Proc. Natl. Acad. Sci. USA, 87, 8835-8839.
36. Twardzik, D.R., Mikovits, J.A., Ranchalis, J.E., Purchio, A.F., Ellingsworth, L. & Ruscetti, F.W, (1990) Gamma-interferon-induced activation of latent transforming growth factor-β by human monocytes. Ann. N.Y. Acad. Sci., 593, 276.
37. Wakefield, L.M., Smith, D.M., Masui, T., Harris, C.C. & Sporn, M.B. (1987) Distribution and modulation of the cellular receptor for transforming growth factor-beta. J. Cell Biol., 105, 965-975.
38. Wakefield, L.M., Smith, D.M., Flanders, K.C. & Spron, M.B. (1988) Latent transforming growth factor-β from human platelets. J. Biol. Chem., 263, 7646-7654.
39. Wolf, G., Mueller, E., Stahl, R.A.K. & Ziyadeh, F.N. (1993) Angiotensin II-induced hypertrophy of cultured murine proximal tubular cells is mediated by endogenous transforming growth factor-β. J. Clin. Invest., 92, 1366-1372.
40. Wolf, Y.G., Rasmussen, L.M. & Ruoslahti, E. (1994) Antibodies against transforming growth factor-β1 suppress intimai hyperplasia in a rat model. J. Clin. Invest., 93, 1172-1178.