A single point mutation in Drosophila dihydrofolate reductase confers methotrexate resistance to a transgenic CHO cell line

Genome

Volumn 46, Issue 4, 2003, Pages 707-715

  Neumann, K ^a   Al Batayneh, K M ^a   Kuiper, M J ^a   Parsons Sheldrake, J ^a   Tyshenko, M G ^a   Flintoff, W F ^b   Cole, S P C ^a   Walker, V K ^a  

^a QUEEN S UNIVERSITY   (Canada)

^b UNIVERSITY OF WESTERN ONTARIO   (Canada)

Author keywords

Dihydrofolate reductase; Drug resistance; Methotrexate; Point mutation

Indexed keywords

ANIMALS; CHO CELLS; CRICETINAE; DROSOPHILA; DRUG RESISTANCE; GENE TRANSFER TECHNIQUES; KINETICS; METHOTREXATE; POINT MUTATION; TETRAHYDROFOLATE DEHYDROGENASE;

CRICETINAE; CRICETULUS GRISEUS; DROSOPHILA MELANOGASTER; INSECTA; MAMMALIA; MELANOGASTER;

EID: 0141674667     PISSN: 08312796     EISSN: None     Source Type: Journal    
DOI: 10.1139/g03-046     Document Type: Article

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