Efficacy of milbemycin oxime in the treatment of canine generalized demodicosis: A retrospective study of 99 dogs (1995-2000)

Veterinary Dermatology

Volumn 14, Issue 4, 2003, Pages 189-195

  Holm, Birgit R ^a  

^a Blå Stjärnan Small Animal Hospital   (Sweden)

Author keywords

Demodex; Demodicosis; Dogs; Milbemycin oxime

Indexed keywords

INTERCEPTOR; MILBEMYCIN; ANTHELMINTIC AGENT; ANTIINFECTIVE AGENT; MACROLIDE; MILBEMYCIN OXIME;

ARTICLE; DEMODEX; DOG; DRUG EFFICACY; INFESTATION; NONHUMAN; RELAPSE; RETROSPECTIVE STUDY; TREATMENT OUTCOME; ANIMAL; ANIMAL DISEASE; DOG DISEASE; EVALUATION; FEMALE; MALE; MITE; ORAL DRUG ADMINISTRATION; PARASITOLOGY; PATHOLOGY; SKIN; SWEDEN;

ACARI; ANIMALIA; CANIS FAMILIARIS; DEMODEX;

ADMINISTRATION, ORAL; ANIMALS; ANTHELMINTICS; ANTI-BACTERIAL AGENTS; DOG DISEASES; DOGS; FEMALE; MACROLIDES; MALE; MITE INFESTATIONS; MITES; SKIN; SWEDEN; TREATMENT OUTCOME;

EID: 0141652983     PISSN: 09594493     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-3164.2003.00339.x     Document Type: Article

References (30)

1. Barriga, O.O., Al-Khalidi, N.W., Martin, S. et al. Evidence of immunosuppression by Demodex canis. Veterinary Immunology and Immunopathology 1992; 32: 37-46.
2. Folz, S.D. Demodicosis (Demodex canis). Compendium on Continuing Education for the Practicing Veterinarian 1983; 5: 116-21.
3. Scott, D.W., Farrow, B.R.H., Schultz, R.D. Studies on the therapeutic and immunologic aspects of generalized demodectic mange in the dog. Journal of the American Veterinary Medical Association 1974; 10: 233-44.
4. Scott, D.W., Miller, W.H., Griffin, C.E. Small Animal Dermatology, 5th edn. W.B. Saunders, Philadelphia, 2001: 417-32.
5. Scott, D.W., Schultz, R.D., Baker, E. Further studies on the therapeutic and immunologic aspects of generalized demodectic mange in the dog. Journal of the American Animal Hospital Association 1976; 12: 203-13.
6. Scott, D.W. Canine demodicosis. Veterinary Clinics of North America: Small Animal Practice 1979; 9: 79-92.
7. Ard, J.W. Successful treatment of generalized demodicosis. Modern Veterinary Practice 1975; 56: 482.
8. Baker, B.B., Stannard, A.A., Yaskulski, S.G. et al. Evaluation of topical application of ronnel solution for generalized demodicosis in dogs. Journal of the American Veterinary Medical Association 1976; 168: 1105-7.
9. Folz, S.D., Geng, S., Nowakowski, L.H. et al. Evaluation of a new treatment for canine scabies and demodicosis. Journal of Veterinary Pharmacology Therapy 1978; 1: 199-204.
10. Duclos, D.D., Jeffers, J.G., Shanley, K.J. Prognosis for treatment of adult onset demodicosis in dogs: 34 cases (1979-90). Journal of the American Veterinary Medical Association 1994; 204: 616-9.
11. Kwochka, K.W., Kunkle, G.A., O'Neill Foil, C. The efficacy of amitraz for generalized demodicosis in dogs: a study of two concentrations and frequencies of application. Compendium on Continuing Education for the Practicing Veterinarian 1985; 7: 8-17.
12. Medleau, L., Willemse, T. Efficacy of daily amitraz on generalised demodicosis in dogs. Journal of Small Animal Practice 1995; 36: 3-6.
13. Medleau, L., Willemse, T. Efficacy of daily amitraz therapy for refractory, generalized demodicosis in dogs: two independent studies. Journal of the American Animal Hospital Association 1995; 31: 246-9.
14. Muller, G.H. Amitraz treatment of demodicosis. Journal of the American Animal Hospital Association 1983; 19: 435-41.
15. Bussiéras, J., Chermette, R. Amitraz and canine demodicosis. Journal of the American Animal Hospital Association 1986; 22: 779-82.
16. Scott, D.W., Walton, D.K. Experience with the use of amitraz and ivermectin for the treatment of generalized demodicosis in dogs. Journal of the American Animal Hospital Association 1985; 21: 535-41.
17. Fondati, F. Efficacy of daily oral ivermectin in the treatment of 10 cases of generalized demodicosis in adult dogs. Veterinary Dermatology 1996; 7: 99-104.
18. Ristic, Z. Ivermectin in the treatment of generalized demodicosis in the dog. Veterinary Dermatology 1993; 4: 40-1.
19. Ristic, Z., Medleau, L., Paradis, M. et al. Ivermectin for treatment of generalized demodicosis in dogs. Journal of the American Veterinary Medical Association 1995; 207: 1308-10.
20. Interceptor Freedom of Information Summary, Ciba-Geigy. (NADA, 140-915)
21. Tranquilli, Wm.J., Paul, A.J., Todd, K.S. Assessment of toxicosis induced by high-dose administration of milbemycin oxime in Collies. American Journal of Veterinary Research 1991; 52: 1170-2.
22. Carlotti, D.N., Guaguere, E., Bourdeau, P. et al. Therapy of generalized demodicosis with variable oral doses of milbemycin oxime in 88 dogs. In: Proceedings of the Third World Congress of Dermatology. ESVD. Edinburgh, 1996: 107.
23. Mueller, R.S., Bettenay, S.V. Milbemycin oxime in the treatment of canine demodicosis. Australian Veterinary Practitioner 1995; 25: 122-5.
24. Garfield, R.A., Reedy, L.M. The use of oral milbemycin oxime (Interceptor®) in the treatment of chronic generalized canine demodicosis. Veterinary Dermatology 1992; 3: 231-5.
25. Miller, W.H., Scott, D.W., Wellington, J.R. et al. Clinical efficacy of milbemycin oxime in the treatment of generalized demodicosis in adult dogs. Journal of the American Veterinary Medical Association 1993; 203: 1426-9.
26. Lemarié, S.L., Hosgood, G., Foil, C.S. A retrospective study of juvenile- and adult-onset generalized demodicosis in dogs (1986-91). Veterinary Dermatology 1996; 7: 3-10.
27. Miller, W.H., Scott, D.W., Cayatte, S.M. et al. Clinical efficacy of increased dosages of milbemycin oxime for treatment of generalized demodicosis in adult dogs. Journal of the American Veterinary Medical Association 1995; 207: 1581-4.
28. Shaw, S.E., Foster, A.P. Treatment of canine adult-onset demodicosis. Australian Veterinary Journal 2000; 78: 243-4.
29. Lemarie, S.L. Canine demodicosis. Compendium on Continuing Education for the Practicing Veterinarian 1996; 18: 354-68.
30. Paradis, M. New approaches to the treatment of canine demodicosis. Veterinary Clinics of North America: Small Animal Practice 1999; 29: 1425-36.