Aminoalkylpyridines (AAPs), triazoline metabolite analogues, as anticonvulsants highly effective in the Mes test

Current Medicinal Chemistry

Volumn 10, Issue 20, 2003, Pages 2109-2121

  Kadaba, Pankaja K ^a   Dixit, Trupti ^b  

^a K and K Biosciences Inc   (United States)

^b TAP Pharmaceuticals   (United States)

Author keywords

Aminoalkylpyridines (AAPs); Epilepsy; MES test; Metabolite analogues; Stroke

Indexed keywords

1 (4 CHLOROPHENYL) 4,5 DIHYDRO 5 (4 PYRIDYL) 1H 1,2,3 TRIAZOLE; 4 AMINOBUTYRIC ACID; ANTICONVULSIVE AGENT; AZIRIDINE; DRUG METABOLITE; ETHOSUXIMIDE; GLUTAMIC ACID; HYDRAZONE DERIVATIVE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; PHENOBARBITAL; PHENYTOIN; PYRIDINE DERIVATIVE; TRIAZOLE DERIVATIVE; TRIAZOLINE DERIVATIVE; VALPROIC ACID;

ACYLATION; ANTICONVULSANT ACTIVITY; BINDING AFFINITY; BRAIN ISCHEMIA; CELL PROTECTION; CEREBROVASCULAR ACCIDENT; CHEMICAL MODIFICATION; DRUG ACTIVITY; DRUG DESIGN; DRUG EFFICACY; DRUG METABOLISM; DRUG SELECTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; ELECTRIC SHOCK; EPILEPSY; MOTOR DYSFUNCTION; NERVE CELL; NEUROCHEMISTRY; NONHUMAN; PHARMACOPHORE; PROTEIN SECRETION; RECEPTOR BINDING; REVIEW; TASK PERFORMANCE;

AMINOPYRIDINES; ANIMALS; ANTICONVULSANTS; BRAIN ISCHEMIA; HUMANS; RECEPTORS, SIGMA; SEIZURES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0141649443     PISSN: 09298673     EISSN: None     Source Type: Journal    
DOI: 10.2174/0929867033456819     Document Type: Review

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