Detection of known mutations in hypertrophic cardiomyopathy using oligonucleotide microarrays assisted by improved base stacking hybridization

Biotechnology Letters

Volumn 25, Issue 19, 2003, Pages 1613-1618

  Wang, Dong ^a,b   Li, Yan ^a,b   Zhang, Rui ^b   Jiang, Di ^b   Ma, Xuemei ^b   Zhou, Yuxiang ^a,b   Cheng, Jing ^a,b  

^a TSINGHUA UNIVERSITY   (China)

^b NATIONAL ENGINEERING RESEARCH CENTER FOR BEIJING BIOCHIP TECHNOLOGY   (China)

Author keywords

Base stacking hybridization; Beta myosin heavy chain; Hypertrophic cardiomyopathy; Microarray; Mutation detection

Indexed keywords

MYOSIN HEAVY CHAIN;

ARTICLE; DNA MICROARRAY; DNA SEQUENCE; EVALUATION; FEASIBILITY STUDY; GENE DELETION; GENE EXPRESSION PROFILING; GENETIC MARKER; GENETIC PREDISPOSITION; GENETIC SCREENING; GENETICS; HUMAN; HYPERTROPHIC CARDIOMYOPATHY; METHODOLOGY; MOLECULAR GENETICS; MUTATION; NUCLEIC ACID HYBRIDIZATION; NUCLEOTIDE SEQUENCE; SEQUENCE ALIGNMENT;

BASE SEQUENCE; CARDIOMYOPATHY, HYPERTROPHIC; DNA MUTATIONAL ANALYSIS; FEASIBILITY STUDIES; GENE EXPRESSION PROFILING; GENETIC MARKERS; GENETIC PREDISPOSITION TO DISEASE; GENETIC SCREENING; HUMANS; MOLECULAR SEQUENCE DATA; MUTATION; MYOSIN HEAVY CHAINS; NUCLEIC ACID HYBRIDIZATION; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; SEQUENCE ALIGNMENT; SEQUENCE ANALYSIS, DNA; SEQUENCE DELETION;

EID: 0141638588     PISSN: 01415492     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1025616015090     Document Type: Article

References (12)

1. Ahrendt SA, Halachmi S, Chow JT, Wu L, Halachmi N, Yang SC, Wehage S, Jen J, Sidransky D (1999) Rapid p53 sequence analysis in primary lung cancer using an oligonucleotide probe array. Proc. Natl. Acad. Sci. USA. 96: 7382-7387.
2. Jeschke B, Uhl K, Weist B, Schroder D, Meitinger T, Dohlemann C, Vosberg HP (1998) A high risk phenotype of hypertrophic cardiomyopathy associated with a compound genotype of two mutated beta-myosin heavy chain genes. Hum. Genet. 102: 299-304.
3. Maldonado-Rodriguez R, Espinosa-Lara M, Calixto-Suarez A, Beattie WG, Beattie KL (1999) Hybridization of glass-tethered oligonucleotide probes to target strands preannealed with labeled auxiliary oligonucleotides. Mol. Biotechnol. 11: 1-12.
4. O'Meara D, Nilsson P, Nygren PA, Uhlen M, Lundeberg J (1998a) Capture of single-stranded DNA assisted by oligonucleotide modules. Anal. Biochem. 255: 195-203.
5. O'Meara D, Yun Z, Sonnerborg A, Lundeberg J (1998b) Cooperative oligonucleotides mediating direct capture of hepatitis C virus RNA from serum. J. Clin. Microbiol. 36: 2454-2459.
6. Seidman CE, Seidman JG (1998) Molecular genetic studies of familial hypertrophic cardiomyopathy. Basic Res. Cardiol. 93 (Suppl 3): 13-16.
7. Southern EM (1996). DNA chips: analysing sequence by hybridization to oligonucleotides on a large scale. Trends Genet. 12: 110-115.
8. Taylor GR (1997). Laboratory Methods for the Detection of Mutations and Polymorphisms in DNA. Boca Raton: CRC Press, 1997.
9. Vasiliskov VA, Prokopenko DV, Mirzabekov AD (2001) Parallel multiplex thermodynamic analysis of coaxial base stacking in DNA duplexes by oligodeoxyribonucleotide microchips. Nucl. Acids Res. 29: 2303-2313.
10. Waldmuller S, Freund P, Mauch S, Toder R, Vosberg HP (2002) Low-density DNA microarrays are versatile tools to screen for known mutations in hypertrophic cardiomyopathy. Human. Mutat. 19: 560-569.
11. Wang D, Gao HF, Zhang R, Ma XM, Zhou YX, Cheng J (2003) Single nucleotide polymorphism discrimination assisted by improved base stacking hybridization using oligonucleotide microarrays. BioTechniques (in press).
12. Yershov G, Barsky V, Belgovskiy A, Kirillov E, Kreindlin E, Ivanov I et al, (1996) DNA analysis and diagnostics on oligonucleotide microchips. Proc. Natl. Acad. Sci. USA 93: 4913-4918.