Immuno-histochemical evaluation of conjunctival remodelling in vernal keratoconjunctivitis

Eye

Volumn 17, Issue 6, 2003, Pages 767-771

  Abu El Asrar, A M ^a   Meersschaert, A ^b   Al Kharashi, S A ^a   Missotten, L ^b   Geboes, K ^b  

^a KING SAUD UNIVERSITY   (Saudi Arabia)

^b UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

Allergy; Conjunctiva; Fibronectin; Laminin; Tenascin; Vernal keratoconjunctivitis

Indexed keywords

FIBRONECTIN; LAMININ; MONOCLONAL ANTIBODY; POLYCLONAL ANTIBODY; SCLEROPROTEIN; TENASCIN;

ADOLESCENT; ARTICLE; BLOOD VESSEL WALL; CLINICAL ARTICLE; CONJUNCTIVAL BIOPSY; CONTROLLED STUDY; EPITHELIUM CELL; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; INFLAMMATORY INFILTRATE; MALE; MICROSCOPY; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; SCHOOL CHILD; VERNAL CONJUNCTIVITIS;

EID: 0141627853     PISSN: 0950222X     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.eye.6700453     Document Type: Article

References (22)

1. Abu El-Asrar AM, Geboes K, Al-Kharashi SA, Al-Mosallam AA, Tabbara KF, Al-Rajhi AA et al. An immunohistochemical study of collagens in trachoma and vernal keratoconjunctivitis. Eye 1998; 12: 1001-1006.
2. Leonardi A, Brun P, Tavolato M, Abatangelo G, Plebani M, Secchi AG: Growth factors and collagen distribution in vernal keratoconjunctivitis. Invest Ophthalmol Vis Sci 2000; 41: 4175-4181.
3. Kusubata M, Hirota A, Ebihara T, Kuwaba K, Matsubara Y, Sasaki T et al. Spatiotemporal changes of fibronectin, tenascin-C, fibulin-1, and fibulin-2 in the skin during the development of chronic contact dermatitis. J Invest Dermatol 1999; 113: 906-912.
4. Jones FS, Jones PL. The tenascin family of ECM glycoproteins: structure, function, and regulation during embryonic development and tissue remodelling. Dev Dyn 2000; 218: 235-259.
5. Chiquet-Ehrismann R, Hagios C, Matsumoto K. The tenascin gene family. Perspect Develop Neurobiol 1994; 2: 3-7.
6. Lin ML, Bertics PJ. Laminin responsiveness is associated with changes in fibroblast morphology, motility, and anchorage-independent growth: cell system for examining the interaction between laminin and EGF signaling pathways. J Cell Physiol 1995; 164: 593-604.
7. Vartio T, Vaheri A. Fibronectin; chains of domains with diversified functions. Trends Biochem Sci 1983; 8: 442-424.
8. Abu El-Asrar AM, Geboes K, Al-Kharashi S, Tabbara KF, Missotten L, Desmet V. Adhesion molecules in vernal keratoconjunctivitis. Br J Ophthalmol 1997; 81: 1099-1106.
9. Abu El-Asrar AM, Fatani RA, Missotten L, Geboes K. Expression of CD23/CD21 and CD40/CD40 ligand in vernal keratoconjunctivitis. Eye 2001; 15: 217-224.
10. Abu El-Asrar AM, Al-Kharashi SA, Al-Mansouri S, Missotten L, Geboes K. Langerhans' cells in vernal keratoconjunctivitis express the costimulatory molecule B7-2 (CD86), but not B7-1 (CD80). Eye 2001; 15: 648-654.
11. Mastuda A, Tagawa Y, Mastuda H. TGF-β2, tenascin, and integrin β1 expression in superior limbic keratoconjunctivitis. Jpn J Ophthalmol 1991; 43: 251-256.
12. Fukuda K, Chikama T, Nakamura M, Nishida T. Differential distribution of subchains of the basement membrane components type IV collagen and laminin among the amniotic membrane, cornea, and conjunctiva. Cornea 1999; 18: 73-79.
13. Linnala A, Kinnula V, Laitinen LA, Lehto V-P, Virtanen I. Transforming growth factor-β regulates the expression of fibronectin and tenascin in BEAS 2β human bronchial epithelial cells. Am J Respir Cell Mol Biol 1995; 13: 578-585.
14. Neubauer K, Kruger M, Quondamatteo F, Knittel T, Saile B, Ramadori G. Transforming growth factor-beta 1 stimulates the synthesis of basement membrane proteins laminin, collagen type IV and entactin in rat liver sinusoidal endothelial cells. J Hepatol 1999; 31: 692-702.
15. Ruegg CR, Chiquet-Ehrismann R, Alkan SS. Tenascin, an extracellular matrix protein, exerts immunomodulatory activities. Proc Natl Acad Sci USA 1989; 86: 7437-7441.
16. Li YQ, Kobayashi M, Yuan L, Wong J, Matsushita K, Hamada JJ et al. Protein kinase C mediates the signal for interferon-gamma mRNA expression in cytotoxic T cells after their adhesion to laminin. Immunology 1998; 93: 455-461.
17. Vliagoftis H, Metcalfe DD. Characterization of adhesive interactions between mast cells and laminin isoforms: evidence of a principal role for α6 integrin. Immunology 1997; 92: 553-560.
18. Ohki K, Kohashi O. Laminin promotes proliferation of bone marrow-derived macrophages and macrophage cell lines. Cell Struct Funct 1994; 19: 63-71.
19. Canfield AE, Schor AM. Evidence that tenascin and thrombospondin-1 modulate sprouting of endothelial cells. J Cell Sci 1995; 108: 797-809.
20. Ponce ML, Nomizu M, Kleinman HK. An angiogenic laminin site and its antagonist bind through the alpha (V) beta 3 and alpha 5 beta 1 integrins. FASEB J 2001; 15: 1389-1397.
21. Khan KMF, Falcone DJ. Role of laminin in matrix induction of macrophage urokinase-type plasminogen activator and 92-kDA metalloproteinase expression. J Biol Chem 1997; 272: 8270-8275.
22. Abu El-Asrar AM, Van Aelst I, Al-Mansouri S, Missotten L, Opdenakker G, Geboes K. Gelatinase B in vernal keratoconjunctivitis. Arch Ophthalmol 2001; 119: 1505-1511.