Imiquimod 5% cream for keloid management

Dermatologic Surgery

Volumn 29, Issue 10, 2003, Pages 1050-1051

  Berman, Brian ^a,b   Villa, Adriana ^a  

^a UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

IMIQUIMOD;

BLISTER; BURNING SENSATION; CHILL; CREAM; DRUG EFFICACY; FATIGUE; FEVER; FLU LIKE SYNDROME; HEADACHE; HUMAN; HYPERPIGMENTATION; INFLAMMATION; KELOID; MYALGIA; NAUSEA; PAIN; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; PRURITUS; RECURRENCE RISK; REVIEW;

ADJUVANTS, IMMUNOLOGIC; ADMINISTRATION, TOPICAL; AMINOQUINOLINES; CHEMOTHERAPY, ADJUVANT; HUMANS; KELOID; RECURRENCE; SURGICAL PROCEDURES, OPERATIVE;

EID: 0141619237     PISSN: 10760512     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1524-4725.2003.29300.x     Document Type: Review

References (7)

1. Shaffer JJ, Taylor SC, Cook-Bolden E Keloidal scars: a review with a critical look at therapeutic options. J Am Acad Dermatol 2002;46:S63-97.
2. Berman B, Flores F. Recurrence rates of excised keloids treated with postoperative triamcinolone acetonide injections or interferon alpha-2b injections. J Am Acad Dermatol 1997;37:755-7.
3. Jimenez SA, Freundlich B, Rosenbloom J. Selective inhibition of diploid fibroblast collagen synthesis by interferons. J Clin Invest 1984;74:1112-6.
4. Berman B, Duncan MR. Short-term keloid treatment in vivo with human interferon alpha-2b results in a selective and persistent normalization of keloidal fibroblast collagen, glycosaminoglycan, and collagenase production in vitro. J Am Acad Dermatol 1989;21:694-706.
5. Kaufman J, Berman B. Topical application of imiquimod 5% cream to excision sites is safe and effective in reducing keloid recurrences. J Am Acad Dermatol 2002;47:S209-11.
6. Clark J. Imiquimod vs. interferon: cream matches injection in terms of eliminating keloid recurrence while showing no adverse events. Dermatol Times December 2002:15-6.
7. Jacobs S, Berman B, Nassiri M, Vincek V. Topical Application of Imiquimod 5% Cream to Keloids Alters Apoptotic Gene Expression. Presented at the American Academy of Dermatology Meeting, San Francisco, March, 2003.