Identification of disease-specific autoantibodies in seronegative myasthenia gravis

Annals of the New York Academy of Sciences

Volumn 998, Issue , 2003, Pages 356-358

  Bartoccioni, Emanuela ^a   Marino, Mariapaola ^a   Evoli, Amelia ^a   Ruegg, Marcus A ^b   Scuderi, Flavia ^a   Provenzano, Carlo ^a  

^a CATHOLIC UNIVERSITY   (Italy)

^b UNIVERSITY OF BASEL   (Switzerland)

Author keywords

Autoantibody; Autoimmunity; Muscle specific kinase; MuSK; Myasthenia gravis; Seronegative myasthenia

Indexed keywords

ANTIGEN; AUTOANTIBODY; IMMUNOGLOBULIN G; MEMBRANE PROTEIN; PYRIDOSTIGMINE;

ANTIBODY SPECIFICITY; BIOTINYLATION; CELL STRAIN; CONFERENCE PAPER; EXTRAOCULAR MUSCLE; HUMAN; IMMUNOPRECIPITATION; IMMUNOREACTIVITY; MYASTHENIA GRAVIS; RESPIRATORY FAILURE; SERODIAGNOSIS; TREATMENT FAILURE;

EID: 0141615838     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1196/annals.1254.041     Document Type: Conference Paper

References (6)

1. MOSSMAN, S., A. VINCENT & J. NEWSOM-DAVIS. 1986. Myasthenia gravis without acetylcholine receptor antibody: a distinct disease entity. Lancet 1: 116-119.
2. PROVENZANO, C., O. ARANCIO, A. EVOLI et al. 1988. Familial autoimmune myasthenia gravis with different pathogenetic antibodies. J. Neurol. Neurosurg. Psychiatry 51: 1228-1230.
3. BLAES, F., D. BEESON, P. PLESTED et al. 2000. IgG from "seronegative" myasthenia gravis patients binds to a muscle cell line, TE671, but not to human acetylcholine receptor. Ann. Neurol. 47: 504-510.
4. HOCH, W., J. MCCONVILLE, S. HELMS et al. 2001. Auto-antibodies to the receptor tyrosine kinase MuSK in patients with myasthenia gravis without acetylcholine receptor antibodies. Nat. Med. 7: 365-368.
5. EVOLI, A., A.P. BATOCCHI, M. LO MONACO et al. 1996. Clinical heterogeneity of seronegative myasthenia gravis. Neuromuscul. Disord. 6: 155-161.
6. SCUDERI, F., M. MARINO, L. COLONNA et al. 2002. Anti-P110 autoantibodies identify a subtype of "seronegative" myasthenia gravis with prominent oculo-bulbar involvement. Lab. Invest. 82: 1139-1146.