Effects of dexamethasone on proliferation, differentiation and apoptosis of adult human osteoblasts in vitro

Chinese Medical Journal

Volumn 116, Issue 9, 2003, Pages 1357-1360

  Yang, Lin ^a   Tao, Tianzun ^b   Wang, Xinting ^b   Du, Ning ^a   Chen, Weizhen ^a   Tao, Shuqing ^b   Wang, Zhicheng ^b   Wu, Liping ^b  

^a SHANGHAI SECOND MEDICAL UNIVERSITY   (China)

^b HARBIN MEDICAL UNIVERSITY   (China)

Author keywords

Apoptosis; Cell culture; Dexamethasone; Differentiation; Osteoblasts; Proliferation

Indexed keywords

ALKALINE PHOSPHATASE; BOVINE SERUM ALBUMIN; CARBON DIOXIDE; COLLAGENASE; DEXAMETHASONE; OSTEOCALCIN; TRYPSIN;

ADULT; APOPTOSIS; ARTICLE; CELL DIFFERENTIATION; CELL ISOLATION; CELL PROLIFERATION; CLINICAL ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CULTURE MEDIUM; DRUG MECHANISM; FEMALE; HUMAN; HUMAN CELL; HUMIDITY; ILIAC BONE; IN VITRO STUDY; INCUBATION TIME; MALE; NICK END LABELING; ORTHOPEDIC SURGERY; OSTEOBLAST; OSTEOPOROSIS; PHASE CONTRAST MICROSCOPE; PROTEIN DEGRADATION; TEMPERATURE MEASUREMENT; TRABECULAR BONE; TRANSMISSION ELECTRON MICROSCOPY;

ADULT; APOPTOSIS; CELL DIFFERENTIATION; CELL DIVISION; CELLS, CULTURED; DEXAMETHASONE; HUMANS; IN SITU NICK-END LABELING; OSTEOBLASTS;

EID: 0141614895     PISSN: 03666999     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (6)

1. Yang L, Tao TZ, Liu FC, et al. Experimental study: the effect of dexamethasone on adult osteoblast proliferation and differentiation. Chin J Orthop (Chin) 2001;21:493-497.
2. Yang L, Tao TZ, Zhang SY, et al. Effects of Chinese traditional medicine Liu-OGN on proliferation and differentiation of adult human osteoblasts in vitro. Chin J Trad Med Traum Orthop (Chin) 2002;10:1-10.
3. Tomoki N, Hitoshi S, Masahiko T, et al. Inhibitory effect of glucocorticoid for osteoblast apoptosis induced by activated peripheral blood mononuclear cells. Endocrinology 1998; 139:2032-2040.
4. Varga FL, Fratzl ZN. Tri-iodothyronine inhibits multilayer formation of the osteoblastic cell line, MC3T3-E1, by promoting apoptosis. J Endocrinol 1999;160:57-65.
5. Lilian I, Plotkin RS, Weinstein A. Prevention of osteocyte and osteoblast apoptosis by bisphosphonates and calcitonin. J Clin Invest 1999;104:1363-1374.
6. Napier JR, Thomas MF, Sharma M, et al. Insulin-like factor-1 protects myoblasts from apoptosis but requires other factors to stimulate proliferation. J Endocrinol 1999;163:63-68.