Potential of neurotoxicity after a single oral dose of 4-bromo-, 4-chloro-, 4-fluoro- or 4-iodoaniline in rats

Journal of Applied Toxicology

Volumn 23, Issue 5, 2003, Pages 315-322

  Okazaki, Yoshimasa ^a   Yamashita, Kotaro ^a   Ishii, Hiroyuki ^a   Sudo, Masato ^a   Tsuchitani, Minoru ^a  

^a MITSUBISHI CHEMICAL CORPORATION   (Japan)

Author keywords

4 bromoaniline; 4 chloroaniline; 4 fluoroaniline; 4 iodoaniline; Hindlimb paralysis; Neurotoxicity; Rat; Spinal cord; Spongy change in white matter

Indexed keywords

4 BROMOANILINE; 4 CHLOROANILINE; 4 FLUOROANILINE; 4 IODOANILINE; ANILINE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN STEM; CENTRAL NERVOUS SYSTEM DISEASE; CONTROLLED STUDY; DOSE RESPONSE; EXTENSOR MUSCLE; FUNCTIONAL ASSESSMENT; GAIT DISORDER; GRIP STRENGTH; HINDLIMB; LETHALITY; MALE; NERVE FIBER DEGENERATION; NEUROTOXICITY; NONHUMAN; OPEN FIELD TEST; PARALYSIS; PERIPHERAL NEUROPATHY; PRIORITY JOURNAL; RAT; RIGHTING REFLEX; SPINAL CORD DISEASE; WHITE MATTER;

ADMINISTRATION, ORAL; ANILINE COMPOUNDS; ANIMALS; BODY WEIGHT; ENVIRONMENTAL POLLUTANTS; HINDLIMB; MALE; NEUROTOXICITY SYNDROMES; RATS; RATS, INBRED STRAINS; SPINAL CORD;

EID: 0141613623     PISSN: 0260437X     EISSN: None     Source Type: Journal    
DOI: 10.1002/jat.921     Document Type: Article

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