Synthesis and antitumor activity of N-sulfonyl derivatives of nucleobases and sulfonamido nucleoside derivatives

Nucleosides, Nucleotides and Nucleic Acids

Volumn 22, Issue 5-8, 2003, Pages 1623-1625

  Zinic B ^a   Krizmanic I ^b   Glavas Obrovac Lj ^c   Karner, I ^c   Zinic M ^a  

^a RUDER BO KOVI INSTITUTE   (Croatia)

^b HERBOS Chem Industry   (Croatia)

^c UNIVERSITY HOSPITAL OSIJEK   (Croatia)

Author keywords

Anhydronucleosides; C 2 sulfonamido pyrimidine nucleosides; In vitro antitumor activity

Indexed keywords

2,2' ANHYDRONUCLEOSIDE DERIVATIVE; 2,3' ANHYDRONUCLEOSIDE DERIVATIVE; NUCLEIC ACID BASE; NUCLEOSIDE DERIVATIVE; PYRIMIDINE NUCLEOSIDE; SULFONAMIDE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; CONFERENCE PAPER; DRUG ACTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IN VITRO STUDY; RING OPENING; STRUCTURE ANALYSIS;

ANTINEOPLASTIC AGENTS; CELL SURVIVAL; FLUOROURACIL; HELA CELLS; HUMANS; KINETICS; MOLECULAR STRUCTURE; NUCLEOSIDES; PURINE NUCLEOSIDES; PYRIMIDINE NUCLEOSIDES; SULFONAMIDES; TUMOR CELLS, CULTURED;

EID: 0141596052     PISSN: 15257770     EISSN: None     Source Type: Journal    
DOI: 10.1081/NCN-120023084     Document Type: Conference Paper

References (4)

1. a) Kašnar, B.; Krizmanić, I.; Žinić, M. Synthesis of the sulfonylpyrimidine derivatives as a new type of sulfonylcycloureas. Nucleosides & Nucleotides 1997, 16, 1067-1071;
2. Žinić B.; Krizmanić, I.; Vikić-Topić, D.; Žinić, M. 5-Bromo- and 5-Iodo-N-1-sulfonylated cytosine derivatives. Exclusive formation of keto-imino tautomers. Croat. Chem. Acta 1999, 72, 957-966.
3. Glavaš-Obrovac, Lj.; Karner, I.; Žinić, B.; Pavelić, K. Antineoplastic activity of novel N-1-sulfonylpyrimidine derivatives. Anticancer Res. 2001, 21, 1979-1986.
4. Žinić, B.; Krizmanić, I.; Vikić-Topić, D.; Srzić, D.; Žinić, M. Synthesis, NMR and MS study of novel N-sulfonylated purine derivatives. Croat. Chem. Acta. 2001, 74, 399-414.