N-acetyl aspartate estimation: A potential method for determining neuronal loss in the transmissible spongiform encephalopathies

Neuropathology and Applied Neurobiology

Volumn 29, Issue 5, 2003, Pages 445-450

  Chung, Y L ^a   Barr, J ^b   Bhakoo, K ^c   Williams, S C R ^d   Bell, J D ^a   Fraser, J R ^b,e  

^a HAMMERSMITH HOSPITAL   (United Kingdom)

^b INSTITUTE FOR ANIMAL HEALTH   (United Kingdom)

^c UNIVERSITY OF OXFORD   (United Kingdom)

^d KING'S COLLEGE LONDON   (United Kingdom)

^e AFRC & MRC Neuropathogenesis Unit   (United Kingdom)

Author keywords

N acetyl aspartate; Neurodegeneration; Neuronal loss; Proton magnetic resonance spectroscopy; Scrapie; Transmissible spongiform encephalopathies

Indexed keywords

BIOCHEMICAL MARKER; N ACETYLASPARTIC ACID;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASSAY; CELL LOSS; CONTROLLED STUDY; CORRELATION ANALYSIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HIPPOCAMPUS; MEASUREMENT; MORPHOMETRICS; MOUSE; NERVE DEGENERATION; NONHUMAN; PRION DISEASE; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; SAMPLE; SCRAPIE;

ANIMALS; ASPARTIC ACID; CELL COUNT; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; HIPPOCAMPUS; MAGNETIC RESONANCE SPECTROSCOPY; MICE; MODELS, ANIMAL; NERVE DEGENERATION; NEURONS; SCRAPIE;

EID: 0141596006     PISSN: 03051846     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2990.2003.00438.x     Document Type: Article

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