-
1
-
-
0025100418
-
Pulmonary delivery of peptide drugs: Effects of particle size on bioavailability of leuprolide acetate in healthy human male volunteers
-
Adjei, A., Garren, J. (1990) Pulmonary delivery of peptide drugs: Effects of particle size on bioavailability of leuprolide acetate in healthy human male volunteers. Pharm. Res. 7: 565-569
-
(1990)
Pharm. Res.
, vol.7
, pp. 565-569
-
-
Adjei, A.1
Garren, J.2
-
2
-
-
0033047323
-
Stability and surface activity of lactate dehydrogenase in spray-dried trehalose
-
Adler, M., Lee, G. (1999) Stability and surface activity of lactate dehydrogenase in spray-dried trehalose. J. Pharm. Sci. 88: 199-208
-
(1999)
J. Pharm. Sci.
, vol.88
, pp. 199-208
-
-
Adler, M.1
Lee, G.2
-
3
-
-
0034001717
-
Optimisation of storage stability of lyophilised Actin using combinations of disaccharides and dextran
-
Allison, S. D., Manning, M. C., Randolph, T. W., Middleton, K., Davis, A., Carpenter, J. F. (2000) Optimisation of storage stability of lyophilised Actin using combinations of disaccharides and dextran. J. Pharm. Sci. 89: 199-214
-
(2000)
J. Pharm. Sci.
, vol.89
, pp. 199-214
-
-
Allison, S.D.1
Manning, M.C.2
Randolph, T.W.3
Middleton, K.4
Davis, A.5
Carpenter, J.F.6
-
4
-
-
0032962882
-
The effect of formulation excipients on protein stability and aerosol performance of spray-dried powders of a recombinant humanised anti-IgE monoclonal antibody
-
Andya, J. D., Maa, Y. F., Costantino, H. R., Nguyen, P. A., Dasovich, N.., Sweeney, T. D., Hsu, C. C., Shire, S. J. (1999) The effect of formulation excipients on protein stability and aerosol performance of spray-dried powders of a recombinant humanised anti-IgE monoclonal antibody. Pharm. Res. 16: 350-358
-
(1999)
Pharm. Res.
, vol.16
, pp. 350-358
-
-
Andya, J.D.1
Maa, Y.F.2
Costantino, H.R.3
Nguyen, P.A.4
Dasovich, N..5
Sweeney, T.D.6
Hsu, C.C.7
Shire, S.J.8
-
5
-
-
0035936969
-
Influence of formulation excipients and physical characteristics of inhalation dry powders on their aerosolisation performance
-
Bosquillon, C., Lombry, C., Preat, V., Vanbever, R. (2001) Influence of formulation excipients and physical characteristics of inhalation dry powders on their aerosolisation performance. J. Control. Release 70: 329-339
-
(2001)
J. Control. Release
, vol.70
, pp. 329-339
-
-
Bosquillon, C.1
Lombry, C.2
Preat, V.3
Vanbever, R.4
-
6
-
-
0032858187
-
Hydroxypropyl-beta-cyclodextrin inhibits spray-drying-induced inactivation of beta-galactosidase
-
Branchu, S., Forbes, R. T., York, P., Petren, S., Nyqvist, H., Camber, O. (1999) Hydroxypropyl-beta-cyclodextrin inhibits spray-drying-induced inactivation of beta-galactosidase. J. Pharm. Sci. 88: 905-911
-
(1999)
J. Pharm. Sci.
, vol.88
, pp. 905-911
-
-
Branchu, S.1
Forbes, R.T.2
York, P.3
Petren, S.4
Nyqvist, H.5
Camber, O.6
-
7
-
-
0028340595
-
The effect of process and formulation variables on the properties of spray dried β-galactosidase
-
Broadhead, J., Rouan, S., Hau, I., Rhodes, C. T. (1994) The effect of process and formulation variables on the properties of spray dried β-galactosidase. J. Pharm. Pharmacol. 46: 458-467
-
(1994)
J. Pharm. Pharmacol.
, vol.46
, pp. 458-467
-
-
Broadhead, J.1
Rouan, S.2
Hau, I.3
Rhodes, C.T.4
-
8
-
-
0031596775
-
Solid state characterisation of spray-dried powders of recombinant human deoxyribonuclease (RhDNase)
-
Chan, H. K., Gonda, I. (1998) Solid state characterisation of spray-dried powders of recombinant human deoxyribonuclease (RhDNase). J. Pharm. Sci. 87: 647-654
-
(1998)
J. Pharm. Sci.
, vol.87
, pp. 647-654
-
-
Chan, H.K.1
Gonda, I.2
-
9
-
-
0031008878
-
Spray dried powders and powder blends of recombinant human deoxyribonuclease (rhDNase) for aerosol delivery
-
Chan, H. K., Clark, A., Gonda, I., Mumenthaler, M., Hsu, C. (1997) Spray dried powders and powder blends of recombinant human deoxyribonuclease (rhDNase) for aerosol delivery. Pharm. Res. 14: 431-437
-
(1997)
Pharm. Res.
, vol.14
, pp. 431-437
-
-
Chan, H.K.1
Clark, A.2
Gonda, I.3
Mumenthaler, M.4
Hsu, C.5
-
10
-
-
0030586287
-
Physical factors affecting the storage stability of freeze-dried Interleukin-1 receptor antagonist: Glass transition and protein conformation
-
Chang, B. S., Beauvais, R. M., Dong, A., Carpenter, J. F. (1996) Physical factors affecting the storage stability of freeze-dried Interleukin-1 receptor antagonist: Glass transition and protein conformation. Arch. Biochem. Biophys. 331: 249-258
-
(1996)
Arch. Biochem. Biophys.
, vol.331
, pp. 249-258
-
-
Chang, B.S.1
Beauvais, R.M.2
Dong, A.3
Carpenter, J.F.4
-
11
-
-
0035313228
-
Emerging protein delivery methods
-
Cleland, J. L., Daugherty, A., Mrsny, R. (2001) Emerging protein delivery methods. Curr. Opin. Biotech. 12: 212-219
-
(2001)
Curr. Opin. Biotech.
, vol.12
, pp. 212-219
-
-
Cleland, J.L.1
Daugherty, A.2
Mrsny, R.3
-
12
-
-
0031793406
-
Effect of mannitol crystallisation on the stability and aerosol performance of a spray-dried pharmaceutical protein, recombinant humanised anti-IgE monoclonal antibody
-
Costantino, H. R., Andya, J. D., Nguyen, P. A., Dasovich, N., Sweeney, T. D., Shire, S. J., Hsu, C. C., Maa, Y. F. (1998) Effect of mannitol crystallisation on the stability and aerosol performance of a spray-dried pharmaceutical protein, recombinant humanised anti-IgE monoclonal antibody. J. Pharm. Sci. 87: 1406-1411
-
(1998)
J. Pharm. Sci.
, vol.87
, pp. 1406-1411
-
-
Costantino, H.R.1
Andya, J.D.2
Nguyen, P.A.3
Dasovich, N.4
Sweeney, T.D.5
Shire, S.J.6
Hsu, C.C.7
Maa, Y.F.8
-
13
-
-
0031953362
-
The role of vitrification in anhydrobiosis
-
Crowe, J. H., Carpenter, J. F., Crowe, L. M. (1998) The role of vitrification in anhydrobiosis. Annu. Rev. Physiol. 60: 73-103
-
(1998)
Annu. Rev. Physiol.
, vol.60
, pp. 73-103
-
-
Crowe, J.H.1
Carpenter, J.F.2
Crowe, L.M.3
-
14
-
-
0031790908
-
Water vapor sorption studies on the physical stability of a series of spray-dried protein/sugar powders for inhalation
-
Forbes, R. T., Davis, K. G., Hindle, M., Clarke, J. G., Maas, J. (1998) Water vapor sorption studies on the physical stability of a series of spray-dried protein/sugar powders for inhalation. J. Pharm. Sci. 87: 316-321
-
(1998)
J. Pharm. Sci.
, vol.87
, pp. 316-321
-
-
Forbes, R.T.1
Davis, K.G.2
Hindle, M.3
Clarke, J.G.4
Maas, J.5
-
15
-
-
0001106314
-
Ideal copolymers and the second-order transitions of synthetic rubbers, I: Non-crystalline copolymer
-
Gordon, M., Taylor, J. S. (1952) Ideal copolymers and the second-order transitions of synthetic rubbers, I: Non-crystalline copolymer. J. Appl. Chem. 2: 493-498
-
(1952)
J. Appl. Chem.
, vol.2
, pp. 493-498
-
-
Gordon, M.1
Taylor, J.S.2
-
16
-
-
0024553924
-
Protective effect of sucrose on spray drying of oxyhemoglobin
-
Labrude, P., Rasolomanana, M., Vigneron, C., Thirion, C., Chaillot, B. (1989) Protective effect of sucrose on spray drying of oxyhemoglobin. J. Pharm. Sci. 78: 223-229
-
(1989)
J. Pharm. Sci.
, vol.78
, pp. 223-229
-
-
Labrude, P.1
Rasolomanana, M.2
Vigneron, C.3
Thirion, C.4
Chaillot, B.5
-
17
-
-
0035041212
-
Turbidimetric and HPLC assays for the determination of formulated lysozyme activity
-
Liao, Y. H., Brown, M. B., Martin, G. P. (2001) Turbidimetric and HPLC assays for the determination of formulated lysozyme activity. J. Pharm. Pharmacol. 53: 549-554
-
(2001)
J. Pharm. Pharmacol.
, vol.53
, pp. 549-554
-
-
Liao, Y.H.1
Brown, M.B.2
Martin, G.P.3
-
18
-
-
0036909494
-
Effects of sucrose and trehalose on the preservation of the native structure of spray-dried lysozyme
-
Liao, Y. H., Brown, M. B., Nazir, T., Quander, A., Martin, G. P. (2002) Effects of sucrose and trehalose on the preservation of the native structure of spray-dried lysozyme. Pharm. Res. 19: 1849-1855
-
(2002)
Pharm. Res.
, vol.19
, pp. 1849-1855
-
-
Liao, Y.H.1
Brown, M.B.2
Nazir, T.3
Quander, A.4
Martin, G.P.5
-
19
-
-
0034537809
-
An investigation of the water-binding properties of protein and sugar systems
-
Lopez-Diez, E. C., Bone, S. (2000) An investigation of the water-binding properties of protein and sugar systems. Phys. Med. Biol. 45: 3577-3588
-
(2000)
Phys. Med. Biol.
, vol.45
, pp. 3577-3588
-
-
Lopez-Diez, E.C.1
Bone, S.2
-
20
-
-
0031914743
-
Spray-drying of air-liquid interface sensitive recombinant human growth hormone
-
Maa, Y. F., Nguyen, P. A. T., Hsu, S. W. (1998a) Spray-drying of air-liquid interface sensitive recombinant human growth hormone. J. Pharm. Sci. 87: 152-159
-
(1998)
J. Pharm. Sci.
, vol.87
, pp. 152-159
-
-
Maa, Y.F.1
Nguyen, P.A.T.2
Hsu, S.W.3
-
21
-
-
0031780284
-
Effect of spray drying and subsequent processing conditions on residual moisture content and physical/biochemical stability of protein inhalation powders
-
Maa, Y. F., Nguyen, P. A., Andya, J. D., Dasovich, N., Sweeney, T. D., Shire, J., Hsu, C. C. (1998b) Effect of spray drying and subsequent processing conditions on residual moisture content and physical/biochemical stability of protein inhalation powders. Pharm. Res. 15: 768-775
-
(1998)
Pharm. Res.
, vol.15
, pp. 768-775
-
-
Maa, Y.F.1
Nguyen, P.A.2
Andya, J.D.3
Dasovich, N.4
Sweeney, T.D.5
Shire, J.6
Hsu, C.C.7
-
22
-
-
0042188063
-
The development of a laser diffraction technique for use in the physical characterisation of dry powders for inhalation
-
Ph. D. Thesis, University of London
-
MacRitchie, H. B. (1998) The development of a laser diffraction technique for use in the physical characterisation of dry powders for inhalation. Ph. D. Thesis, University of London
-
(1998)
-
-
MacRitchie, H.B.1
-
23
-
-
0033397255
-
Enhancement of the foaming properties of protein dried in the presence of trehalose
-
Murray, B. S., Liang, H. J. (1999) Enhancement of the foaming properties of protein dried in the presence of trehalose. J. Agric. Food Chem. 47: 4984-4991
-
(1999)
J. Agric. Food Chem.
, vol.47
, pp. 4984-4991
-
-
Murray, B.S.1
Liang, H.J.2
-
24
-
-
84985209709
-
Phase-transitions of amorphous sucrose and frozen sucrose solutions
-
Roos, Y., Karel, M. (1991) Phase-transitions of amorphous sucrose and frozen sucrose solutions. J. Food Sci. 56: 266-267
-
(1991)
J. Food Sci.
, vol.56
, pp. 266-267
-
-
Roos, Y.1
Karel, M.2
-
25
-
-
0028147099
-
Non-isothermal and isothermal crystallization of sucrose from the amorphous state
-
Saleki-Gerhardt, A., Zografi, G. (1994) Non-isothermal and isothermal crystallization of sucrose from the amorphous state. Pharm. Res. 11: 1166-1173
-
(1994)
Pharm. Res.
, vol.11
, pp. 1166-1173
-
-
Saleki-Gerhardt, A.1
Zografi, G.2
-
26
-
-
0031048684
-
Effects of bovine somatotropin (rbSt) concentration at different moisture levels on the physical stability of sucrose in freeze-dried rbSt/Sucrose mixtures
-
Sarciaux, J. M. E., Hageman, M. J. (1997) Effects of bovine somatotropin (rbSt) concentration at different moisture levels on the physical stability of sucrose in freeze-dried rbSt/Sucrose mixtures. J. Pharm. Sci. 86: 365-371
-
(1997)
J. Pharm. Sci.
, vol.86
, pp. 365-371
-
-
Sarciaux, J.M.E.1
Hageman, M.J.2
-
27
-
-
0032784693
-
The effects of absorbed water on the properties of amorphous mixtures containing sucrose
-
Shamblin, S. L., Zografi, G. (1999) The effects of absorbed water on the properties of amorphous mixtures containing sucrose. Pharm. Res. 16: 1119-1124
-
(1999)
Pharm. Res.
, vol.16
, pp. 1119-1124
-
-
Shamblin, S.L.1
Zografi, G.2
-
28
-
-
84961475078
-
Non-equilibrium behaviour of small carbohydrate water system
-
Slade, L., Levine, H. (1988) Non-equilibrium behaviour of small carbohydrate water system. Pure Appl. Chem. 60: 1841-1864
-
(1988)
Pure Appl. Chem.
, vol.60
, pp. 1841-1864
-
-
Slade, L.1
Levine, H.2
-
29
-
-
0033046866
-
Activity-stability considerations of trypsinogen during spray drying: Effects of sucrose
-
Tzannis, S. T., Prestrelski, S. J. (1999) Activity-stability considerations of trypsinogen during spray drying: Effects of sucrose. J. Pharm. Sci. 88: 351-359
-
(1999)
J. Pharm. Sci.
, vol.88
, pp. 351-359
-
-
Tzannis, S.T.1
Prestrelski, S.J.2
-
30
-
-
0026355904
-
Recent progress in protein and peptide delivery by noninvasive routes
-
Wearley, L. L. (1991) Recent progress in protein and peptide delivery by noninvasive routes. Crit. Rev. Ther. Drug 8: 331-394
-
(1991)
Crit. Rev. Ther. Drug
, vol.8
, pp. 331-394
-
-
Wearley, L.L.1
|