Insular carcinoma of the thyroid in an adolescent: A case report and review of the literature

Current Opinion in Pediatrics

Volumn 15, Issue 5, 2003, Pages 512-515

  Yusuf, Kamran ^a   Reyes Mugica, Miguel ^a   Carpenter, Thomas O ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Cancer; Differentiated thyroid cancer; Follicular thyroid neoplasm; Neck mass; Papillary thyroid neoplasm; Radioiodine; Thyroglobulin; Undifferentiated thyroid cancer

Indexed keywords

ADOLESCENT DISEASE; ASPIRATION BIOPSY; CANCER DIAGNOSIS; CASE REPORT; CLINICAL FEATURE; COMPUTER ASSISTED TOMOGRAPHY; DISEASE COURSE; FEMALE; HEMODYNAMIC MONITORING; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; LABORATORY TEST; LYMPH NODE DISSECTION; NUCLEAR MAGNETIC RESONANCE IMAGING; PHYSICAL EXAMINATION; PRIORITY JOURNAL; REVIEW; THYROID CARCINOMA; THYROIDECTOMY; ULTRASOUND;

ADOLESCENT; CARCINOMA, PAPILLARY; FEMALE; GENES, RAS; HUMANS; MUTATION; PROGNOSIS; THYROID NEOPLASMS; THYROIDECTOMY;

EID: 0141562224     PISSN: 10408703     EISSN: None     Source Type: Journal    
DOI: 10.1097/00008480-200310000-00010     Document Type: Review

References (36)

1. Poplack DG, Chrousos GP: Thyroid carcinoma. In Pediatric Oncology. Edited by Pizzo PA. Philadelphia: JB Lippincott Co.; 1989:741-743.
2. Altic JN: Carcinoma of the thyroid in children and adolescents. In Pediatric Endocrinology, edn 3. Edited by Lifshitz F. New York: Marcel Dekker; 1996:423-430.
3. Carcanigu ML, Zampi G, Rosai J: Poorly differentiated ("insular") thyroid carcinoma. A reinterpretation of Langhan's " wuchernde struma. Am J Surg Pathology 1984, 8:655-668.
4. Langhans T: Uber die epithelialen formen der malignen struma. Virchows Arch 1907, 189:69-188.
5. Flynn SD, Forman BH, Stewart AF, et al.: Poorly differentiated ("insular") carcinoma of the thyroid gland: An aggressive subset of differentiated thyroid neoplasms. Surgery 1988, 104:963-970.
6. Justin EP, Seabold JE, Robinson RA, et al.: Insular carcinoma: A distinct thyroid carcinoma with associated iodine - 131 localization. J Nucl Med 1991, 32:1358-1363.
7. Pellegritti G, Giuffrida D, Scollo C, et al.: Long-term outcome of patients with insular carcinoma of the thyroid. Cancer 2002, 95:2076-2085.
8. Lo CY, Lam KY, Wan KY: Insular thyroid carcinoma in adolescents. Eur J Surg 2000, 166:585-588.
9. Hassoun AAK, Hay ID, Goellner JR, et al.: Insular thyroid carcinoma in adolescents. Cancer 1997, 79:1044-1048.
10. Zetting G, Kaserer K, Passler C, et al.: Advanced thyroid carcinoma in a fourteen-year old girl: Twenty-four years follow-up. Thyroid 2000, 5:435-437.
11. Rodriguez JM, Parrilla P, Moreno A, et al.: Insular carcinoma: An infrequent subtype of thyroid cancer. J Am Coll Surg 1998, 187:503-508.
12. Pilotti S, Collini P, Mariani L, et al.: Insular carcinoma: A distinct de novo entity among follicular carcinomas of the thyroid gland. Am J Surg Pathol 1997, 21:1466-1473.
13. Kotiloglu E, Kale G, Senocak ME: Follicular thyroid carcinoma with a predominant insular component in a child: A case report. Tumori 1995, 81:296-298.
14. Sironi M, Collini P, Cantaboni A: Fine needle aspiration cytology of insular thyroid carcinoma: A report of four cases. Acta Cytol 1992, 36:435-439.
15. Russo D, Tumino S, Arturi F, et al.: Detection of an activating mutation of the thyrotropin receptor in a case of an autonomously hyper functioning thyroid insular carcinoma. J Clin Endocrinol Metab 1997, 82:735-738.
16. Albareda M, Puig-Domingo M, Wengrowicz S, et al.: Clinical forms of presentation and evolution of diffuse sclerosing variant of papillary carcinoma and insular variant of follicular carcinoma of the thyroid. Thyroid 1998, 8:385-391.
17. Dominguez-Malagon H, Guerrero-Medrano J, Suster S: Ectopic poorly differentiated (insular) carcinoma of the thyroid. Report of a case presenting as an anterior mediastinal mass. Am J of Clinical Pathology 1995, 104:408-412.
18. Bose S, Ravindra N, Girdhar G, et al.: Clavicular metastsis of insular carcinoma of the thyroid showing increased uptake in the presence of a functioning thyroid gland. Clin Nuc Med 1998, 23:774-775.
19. Ganly I, Crowther J: Insular carcinoma of thyroid presenting as cervical cord compression. J Laryngology/Otology 2000, 114:808-810.
20. Gorlin JB, Allan SE: Thyroid cancer in children. Endocrinal Metab Clin North Am 1990, 19:649-662.
21. Layfield LJ, Gopez EV: Insular carcinoma of the thyroid: report of a case with intact insulae and microfollicular structures. Diagn Cytopathol 2000, 23:409-413.
22. Nguyen G, Akin MM: Cytopathology of insular carcinoma of the thyroid. Diagn Cytopathol 2001, 25:325-330.
23. Guiter GE, Auger M, Ali SZ, et al.: Cytopathology of insular carcinoma of the thyroid. Cancer 1999, 87:196-202.
24. Zakowski MF, Schlesinger K, Mizrachi HH: Cytopathologic features of poorly differentiated "insular" carcinoma of the thyroid. A case report. Acta Cytol 1992, 36:523-526.
25. Ashfaq R, Vuitch F, Delgado R, et al.: Papillary and follicular thyroid carcinomas with an insular component. Cancer 1994, 73:416-423.
26. Albores-Saavedra J, Housini I, Vuitch F, et al.: Macrofollicular variant of papillary thyroid carcinoma with minor insular component. Cancer 1997, 80:1110-1116.
27. Jorda M, Gonzalez-Campora R, Mora J, et al.: Prognostic factors in follicular carcinoma of the thyroid. Arch Pathol Lab Med 1993, 117:631-635.
28. Machens A, Hinze R, Lautenschlager C, et al.: Multivariate analysis of clinicopathologic parameters for the insular subtype of differentiated thyroid carcinoma. Arch Surg 2001, 136:941-944.
29. Papotti M, Micca B, Favero A, et al.: Poorly differentiated thyroid carcinomas with primordial cell component. Am J Surg Pathol 1993, 17:291-301.
30. Lemoine NR, Maijall ES, Wyllie FS, et al.: High frequency of ras oncogene activation in all stages of thyroid tumori genesis. Oncogene 1989, 4:159-164.
31. Mamenti G, Pilotti S, Re FC: Della Porta G, Pierotti M A. Selective activation of ras oncogenes in follicular and undifferentiated thyroid carcinomas. Eur J Cancer 1994, 30:987-993.
32. Takeuchi Y, Daa T, Kashima K, et al.: Mutations of p53 in thyroid carcinoma with an insular component. Thyroid 1999, 9:377-381.
33. Lam K, Lo C, Chan K, Awn K: Insular and anaplastic carcinoma of the thyroid: A 45-year comparative study at a single institution and a review of the significance of p53 and p21. Ann Surg 2000, 231:329-338.
34. Pesterli HE, Ogus M, Oren N, et al.: Bcl-2 and p53 expression a well-differentiated thyroid carcinoma with an insular pattern. Endocrine Pathology 2001, 12:310-395.
35. Wang S, Lloyd RV, Hutzler MJ, et al.: The rote of cell cycle regulatory protein, Cyclin D1, in the progression of thyroid cancer. Mod Pathol 2000, 13:882-887.
36. Bal C, Padhy AK, Panda S, et al.: Insular" carcinoma of thyroid a subset of anaplastic thyroid malignancy with a less aggressive course. Clin Nuc Med 1993, 18:1056-1058.