A randomized controlled trial of inhaled flunisolide in the management of acute asthma in children

Chest

Volumn 124, Issue 3, 2003, Pages 790-794

  Nakanishi, Albert K ^a   Klasner, Ann K ^b   Rubin, Bruce K ^c  

^a SAINT LOUIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b University of Alabama at Birmingham   (United States)

^c WAKE FOREST SCHOOL OF MEDICINE   (United States)

Author keywords

Acute childhood asthma; Inhaled corticosteroids; Metered dose inhaler; Oral corticosteroids; Randomized controlled study; Spirometry

Indexed keywords

ANTIASTHMATIC AGENT; CORTICOSTEROID; FLUNISOLIDE; PREDNISONE;

ADOLESCENT; ASTHMA; CHILD; CHILDHOOD DISEASE; CONFERENCE PAPER; CONTROLLED STUDY; DISEASE EXACERBATION; DISEASE SEVERITY; EMERGENCY TREATMENT; FEMALE; FORCED EXPIRATORY VOLUME; GENDER; HUMAN; HYPOTHESIS; MAJOR CLINICAL STUDY; MALE; METERED DOSE INHALER; PRIORITY JOURNAL; RACE; SIDE EFFECT; SPIROMETRY; STATISTICAL ANALYSIS; STATISTICAL SIGNIFICANCE;

EID: 0141558832     PISSN: 00123692     EISSN: None     Source Type: Journal    
DOI: 10.1378/chest.124.3.790     Document Type: Conference Paper

References (36)

1. National Asthma Education and Prevention Program. Expert panel report 2: Guidelines for the diagnosis and management of asthma. Bethesda, MD: National Institute of Health, April 1997; Publication No. 97-405
2. Barnes PJ. A new approach to the treatment of asthma. N Engl J Med 1989; 321:1517-1527
3. Reed CE. Glucocorticoids in asthma. Immunol Allergy Clin North Am 1993; 13:903-915
4. Shapiro GG. Steroids and asthma. Pediatrics 1995; 96:347-348
5. Rubin BK, Marcushamer S, Priel I, et al. State of the art: emergency management of the child with acute asthma. Pediatr Pulmonol 1990; 8:45-57
6. Rowe BH, Keller JL, Oxman AD. Effectiveness of steroid therapy in acute exacerbations of asthma: a meta-analysis. Am J Emerg Med 1992; 10:301-310
7. Munck A, Mendel DB, Smith LI. Glucocorticoid receptors and actions. Am Rev Respir Dis 1990; 141:S2-S10
8. Barnes NC. Effect of glucocorticoids in acute severe asthma. Thorax 1992; 47:582-583
9. Schleimer RP. Effect of glucocorticoids on inflammatory cells relevant to their therapeutic application in asthma. Am Rev Respir Dis 1990; 141:S59-S69
10. Wasserfallen JB, Baraniuk JN. Clinical use of inhaled corticosteroids. J Allergy Clin Immunol 1996; 97:177-182
11. McGill K, Joseph B, Busse W. Corticosteroids in the treatment of asthma: practiced recommendations. Clin Immunother 1995; 4:16-48
12. Rowe BH, Keller JL, Oxman AD. Effectiveness of steroid therapy in acute exacerbation of asthma: a meta analysis. Am J Emerg Med 1992; 10:301-310
13. Tal A, Levy N, Bearman JE. Methylprednisone therapy for acute asthma in infants and toddlers: a controlled clinical trial. Pediatrics 1990; 86:350-356
14. Littenberg B, Gluck EH. A controlled trial of methylprednisolone in the emergency treatment of acute asthma. N Engl J Med 1986; 314:150-152
15. Gries DM, Moffitt DR, Pulos ER, et al. A single dose of intramuscularly administered dexamethasone acetate is as effective as oral prednisone to treat asthma exacerbations in young children. J Pediatr 2000; 136:298-303
16. Klig JE, Hodge D, Rutherford MW. Symptomatic improvement following emergency department management of asthma: a pilot study of intramuscular dexamethasone versus oral prednisone. J Asthma 1997; 34:419-425
17. Chapman KR, Verbeek PR, White JG, et al. Effect of a short course of prednisone in the prevention of early relapse after the emergency treatment of acute asthma. N Engl J Med 1991; 324:788-794
18. Scarfone RJ, Fuchs S, Nager AL, et al. Controlled trial of oral prednisone in the emergency department treatment of children with acute asthma. Pediatrics 1993; 92:513-518
19. Barnes PJ, Pedersen S. Efficacy and safety of inhaled corticosteroids in asthma. Am Rev Respir Dis 1993; 148:S1-S26
20. Kasper WJ, Howe PM. Fatal varicella after a single course of corticosteroids. Pediatr Infect Dis J 1990; 9:729-732
21. Allen DB. Growth suppression by glucocorticoid therapy. Endocrinol Metab Clin North Am 1996; 25:699-717
22. American Thoracic Society. Standardization of spirometry, 1994 update. Am J Respir Crit Care Med 1994; 152:1107-1136
23. Nakanishi AK, Lamb BM, Foster C, et al. Ultrasonic nebulization of albuterol is no more effective than jet nebulization for the treatment of acute asthma in children. Chest 1997; 111:1505-1508
24. Rodrigo G, Rodrigo C. Corticosteroids in the emergency department therapy of acute adult asthma: an evidence-based evaluation. Chest 1999; 116:285-295
25. Rodrigo G, Rodrigo C. Inhaled flunisolide for acute asthma. Am J Respir Crit Care Med 1998; 157:698-703
26. Volovitz B, Bentur L, Finklestein Y. Effectiveness and safety of inhaled corticosteroids in controlling acute asthma attacks in children who were treated in the emergency department: a controlled comparative study with oral prednisone. J Allergy Clin Immunol 1998; 102:605-609
27. Devidayal S, Singhi S, Kumar L, et al. Efficacy of nebulized budesonide compared to oral prednisone in acute bronchial asthma. Acta Pediatr 1999; 88:835-840
28. Matthews EE, Curtis PD, McLain BI, et al. Nebulized budesonide versus oral steroids in severe exacerbations of childhood asthma. Acta Paediatr 1999; 88:841-843
29. Scarfone RJ, Loiselle JM, Wiley JF, et al. Nebulized dexamethasone versus oral prednisone in the emergency treatment of asthmatic children. Ann Emerg Med 1995; 26:480-486
30. Schuh S, Reisman J, Alshehri M, et al. A comparison of inhaled fluticasone and oral prednisone for children with severe acute asthma. N Engl J Med 2000; 343:689-694
31. Rubin BK, Fink JB. Aerosol therapy for children. Respir Care Clin N Am 2001; 7:175-213
32. Barnes PJ. Inhaled glucocorticoids for asthma. N Engl J Med 1995; 332:868-875
33. Newman SP, Millar AB, Lennard-Jones TR. Improvement of pressurized aerosol deposition with Nebuhaler spacer device. Thorax 1984; 39:935-941
34. Amirav I, Newhouse MT. Metered dose inhalers accessory devices in acute asthma: efficacy and comparison with nebulizers; a literature review. Arch Pediatr Adolesc Med 1997; 151:876-882
35. Simmons MS, Nides MA, Rand CS, et al. Unpredictability of deception in compliance with physician-prescribed bronchodilator inhaler use in a clinical trial. Chest 2000; 118:290-295
36. Cote J, Cartier A, Malo JL, et al. Compliance with peak expiratory flow monitoring in home management of asthma. Chest 1998; 113:968-972