Measurement of the extracellular space in brain tumors using 76Br-bromide and PET

Journal of Nuclear Medicine

Volumn 44, Issue 8, 2003, Pages 1210-1218

  Bruehlmeier, Matthias ^a,b   Roelcke, Ulrich ^b   Bläuenstein, Peter ^a   Missimer, John ^a   Schubiger, Pius A ^a   Locher, Johannes Th ^b   Pellikka, Raimo ^a   Ametamey, Simon M ^a  

^a ETH Zurich   (Switzerland)

^b CANTONAL HOSPITAL AARAU   (Switzerland)

Author keywords

76Br bromide PET; Brain tumor; Extracellular space; Pathophysiology

Indexed keywords

BROMIDE; BROMIDE 76; DEXAMETHASONE; UNCLASSIFIED DRUG; BROMINE; DIAGNOSTIC AGENT; RADIOPHARMACEUTICAL AGENT; SODIUM BROMIDE; SODIUM DERIVATIVE;

ARTERIAL BLOOD; ARTICLE; BRAIN EDEMA; BRAIN REGION; BRAIN TUMOR; CANCER PATIENT; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG DISTRIBUTION; DRUG UPTAKE; EVALUATION; EXPERIMENTAL MODEL; EXTRACELLULAR SPACE; HUMAN; INTERMETHOD COMPARISON; OCCIPITAL LOBE; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; RELIABILITY; TUMOR VOLUME; ADULT; AGED; ASTROCYTOMA; BLOOD; CANCER STAGING; CLINICAL TRIAL; COMPUTER ASSISTED EMISSION TOMOGRAPHY; FEMALE; GLIOBLASTOMA; IMAGE ENHANCEMENT; LYMPHOMA; MALE; MENINGIOMA; METABOLIC CLEARANCE RATE; METABOLISM; METHODOLOGY; MIDDLE AGED; SCINTISCANNING;

ADULT; AGED; ASTROCYTOMA; BRAIN EDEMA; BRAIN NEOPLASMS; BROMIDES; BROMINE RADIOISOTOPES; EXTRACELLULAR SPACE; FEMALE; GLIOBLASTOMA; HUMANS; IMAGE ENHANCEMENT; LYMPHOMA; MALE; MENINGIOMA; METABOLIC CLEARANCE RATE; MIDDLE AGED; NEOPLASM STAGING; RADIOPHARMACEUTICALS; SODIUM COMPOUNDS; TOMOGRAPHY, EMISSION-COMPUTED;

EID: 0141557978     PISSN: 01615505     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (27)

1. Klatzo I. Neuropathological aspects of brain edema J Neuropathol Exp Neurol. 1967;26:1-14.
2. Bakay L. The extracellular space in brain tumors. I. Morphological considerations. Brain 1970;93:693-698.
3. Gullino PM, Grantham FH, Smith SH. The interstitial water space in tumors. Cancer Res 1965;25:727-731.
4. Yoshii Y, Sugiyama K. Intercapillary distance in the proliferating area of human glioma. Cancer Res. 1988;48:2938-2941.
5. Jolesz FA, Schwartz RB, Guttmann CRG. Diagnostic imaging in malignant gliomas. In. Black PM, Schoene WC, Lampson LA, eds. Astrocytomas: Diagnosis, Treatment, and Biology. Boston, MA: Blackwell Scientific; 1993:37-49.
6. Eis M, Els T, Hoehn-Berlage M, et al. Quantitative diffusion MR imaging of cerebral tumor and edema. Acta Neurochir Suppl (Wien). 1994;60:344-346.
7. Nicholson C, Sykova E. Extracellular space structure revealed by diffusion analysis. Trends Neurosci. 1998;21:207-215.
8. Kim J, Wang Z, Gallagher D, et al. Extracellular water, sodium bromide dilution estimates compared with other markers in patients with acquired immunodeficiency syndrome. J Parenter Enteral Nutr. 1999;23:61-66.
9. Söremark R. Distribution and kinetics of bromide ions in the mammalian body. Acta Radiol Suppl. 1960;190:64-105.
10. Rauws AG, van Logten MJ. The influence of dietary chloride on bromide excretion in the rat. Toxicology. 1975;3:29-32.
11. Smith QR, Pershing LK, Johanson CE. A comparative analysis of extracellular fluid volume of several tissues as determined by six different markers. Life Sci. 1981;29:449-456.
12. Staffurth JS, Birchall I. The measurement of the extracellular fluid volume by radioactive bromine Clin Sci. 1960;19:43-53.
13. Syrota A, Samson Y, Boullais C, et al. Tomographic mapping of brain intracellular pH and extracellular water space in stroke patients. J Cereb Blood Flow Metab. 1985;5:358-368.
14. de Villiers D, Nortier M, Richter W. Experimental and theoretical excitation functions for natBr(p,x) reactions. Appl Radiat Isot. 2002;57:907-913.
15. Söremark R. The biological half-life of bromide ions in human blood. Acta Physiol Scand. 1960;50:119-123.
16. Vaisemann N, Koren G, Pencharz P Pharmacokinetics of oral and intravenous bromide in normal volunteers. Clin Toxicol. 1986;24:403-413.
17. Kreel BK. An improved bromide assay for the estimation of extracellular water volume by capillary gas chromatography. Clin Chim Acta. 1994;231:117-128.
18. Mikolajczyk K, Szabatin M, Rudnicki P, et al A JAVA environment for medical image data analysis: initial application for brain PET quantitation Med Inform (Lond). 1998;23:207-214.
19. Hawkins RA, Phelps ME, Huang SC. Effects of temporal sampling, glucose metabolic rates, and disruptions of the blood-brain barrier on the FDG model with and without a vascular compartment: studies in human brain tumors with PET. J Cereb Blood Flow Metab 1986;6:170-183.
20. 11C-methyl]-(-)-cocaine PET studies in human subjects. J Cereb Blood Flow Metab. 1990;10: 740-747.
21. Patlak CS, Blasberg RG, Fenstermacher JD. Graphical evaluation of blood-to-brain transfer constants from multiple-time uptake data. J Cereb Blood Flow Metab 1983;3:1-7.
22. Jain RK. Therapeutic implications of tumor physiology Curr Opin Oncol. 1991;3:1105-1108.
23. Tofts PS, Kermode AG Measurement of the blood-brain barrier permeability and leakage space using dynamic MR imaging. 1. Fundamental concepts Magn Reson Med. 1991;17:357-367.
24. Ludemann L, Hamm B, Zimmer C. Pharmacokinetic analysis of glioma compartments with dynamic Gd-DTPA-enhanced magnetic resonance imaging. Magn Reson Imaging. 2000;18:1201-1214.
25. Levin VA, Fenstermacher JD, Patlak CS. Sucrose and inulin space measurements of cerebral cortex in four mammalian species. Am J Physiol. 1970;219:1528-1533.
26. Cragg B. Preservation of extracellular space during fixation of the brain for electron microscopy. Tissue Cell. 1980;12:63-72.
27. 125I]albumin distribution in experimental RG-2 gliomas and adjacent brain. J Cereb Blood Flow Metab. 1987;7:687-701.