Aspirin and warfarin versus aspirin monotherapy after myocardial infarction

Annals of Pharmacotherapy

Volumn 37, Issue 10, 2003, Pages 1502-1505

  Jeddy, Azzah S ^a   Gleason, Brenda L ^a  

^a ST LOUIS COLLEGE OF PHARMACY   (United States)

Author keywords

Aspirin; Combination therapy; Myocardial infarction; Secondary prevention; Warfarin

Indexed keywords

ACETYLSALICYLIC ACID; WARFARIN;

BLEEDING; DEATH; GASTROINTESTINAL HEMORRHAGE; HEART INFARCTION; HIGH RISK PATIENT; HUMAN; ISCHEMIC HEART DISEASE; LOW DRUG DOSE; MONOTHERAPY; PRIORITY JOURNAL; REVIEW; RISK ASSESSMENT; THROMBOEMBOLISM;

ASPIRIN; DRUG INTERACTIONS; DRUG THERAPY, COMBINATION; HUMANS; MYOCARDIAL INFARCTION; WARFARIN;

EID: 0141557894     PISSN: 10600280     EISSN: None     Source Type: Journal    
DOI: 10.1345/aph.1C474     Document Type: Review

References (15)

1. 2002 Heart and stroke statistical update. Dallas, TX: American Heart Association, 2001.
2. Shah PK. Pathophysiology of coronary thrombosis: role of plaque rupture and plaque erosion. Prog Cardiovasc Dis 2002;44:357-68.
3. Bahit MC, Granger CB, Wallentin L. Persistence of the prothrombotic state after coronary syndromes: implications for treatment. Am Heart J 2002;143:205-16.
4. Stringer KA, Lopez LM. Uncomplicated myocardial infarction. In: Dipiro JT, Talbert RL, Yee GC, Matzke GR, Wells BG, Posey LM. Pharmacotherapy - a pathophysiologic approach. 5th ed. New York: McGraw-Hill, 2002:251-7.
5. Becker RC. Antithrombotic therapy after myocardial infarction. N Engl J Med 2002;347:1019-21.
6. Antiplatelet Trialists' Collaboration. Collaborative overview of randomized trials of antiplatelet therapy. I: Prevention of death, myocardial infarction, and stroke by prolonged antiplatelet therapy in various categories of patients. BMJ 1994;308:81-106.
7. Smith P, Arnesen H, Holme I. The effect of warfarin on mortality and reinfarction after myocardial infarction. N Engl J Med 1990;323:147-52.
8. Meijer A, Verheugt FWA, Werter CJ, Lie KI, van der Pol JM, van Eenige MJ. Aspirin versus Coumadin in the prevention of reocclusion and recurrent ischemia after successful thrombolysis: a prospective placebo-controlled angiographic study. Results of the APRICOT study. Circulation 1993;87:1524-30.
9. ASPECT Research Group. Effect of long-term oral anticoagulant treatment on mortality and cardiovascular mortality after myocardial infarction: Anticoagulants in the Secondary Prevention of Events In Coronary Thrombosis (ASPECT) Research Group. Lancet 1994;90:499-533.
10. Huynh T, Theroux P, Bogaty P, Nasmith J, Solymoss S. Aspirin, warfarin, or the combination for secondary prevention of coronary events in patients with acute coronary syndromes and prior coronary artery bypass surgery. Circulation 2001;103:3069-74.
11. Ryan TJ, Antman EM, Brooks NH, Califf RM, Hillis LD, Hiratzka LF, et al. 1999 update: ACC/AHA guidelines for the management of patients with acute myocardial infarction. A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee on Management of Acute Myocardial Infarction). www.acc.org (accessed 2002 Nov 11).
12. Coumadin Aspirin Reinfarction Study (CARS) Investigators. Randomised double-blind trial of fixed low-dose warfarin with aspirin after myocardial infarction. Lancet 1997;350:389-96.
13. Fiore LD, Ezekowitz MD, Brophy MT, Lu D, Sacco J, Peduzzi P, et al. Department of Veterans Affairs cooperative studies program clinical trial comparing combined warfarin and aspirin with aspirin alone in survivors of acute myocardial infarction: primary results from the CHAMP study. Circulation 2002;105:557-63.
14. van Es RF, Jonker JJ, Verheugt FWA, Deckers JW, Grobbee DE. Aspirin and Coumadin after acute coronary syndromes (the ASPECT-2 study): a randomised controlled trial. Lancet 2002;360:109-13.
15. Hurlen M, Abdelnoor M, Smith P, Erikssen J, Arnesen H. Warfarin, aspirin, or both after myocardial infarction. N Engl J Med 2002;347:969-74.